Gene/Proteome Database (LMPD)

LMPD ID
LMP014072
Gene ID
574110
Species
Macaca mulatta (Rhesus monkey)
Gene Name
estrogen receptor 2 (ER beta)
Gene Symbol
ESR2
Alternate Names
estrogen receptor beta; ER-beta; nuclear receptor subfamily 3 group A member 2;
Chromosome
7
Map Location
chromosome:7

Proteins

estrogen receptor beta
Refseq ID NP_001252750
Protein GI 388490243
UniProt ID F6UFU5
mRNA ID NM_001265821
Length 530
Protein sequence is identical to GI:109083915 (mRNA isoform)
Refseq ID XP_002805112
Protein GI 297298035
UniProt ID F6UFU5
mRNA ID XM_002805066
Length 499
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVESHHEYPAMTFYSPAVMNYSSPSNVTNLEGGPGRQTASPNVLWPTPGHLSPLAVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCTSPVTSPSSKRDAHFCAVCSDFASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCASKAKRSGSHAPLVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSNMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHARAEKASHSLTSFGMEDGDTLLPEATDGSVTF
Refseq ID XP_001101433
Protein GI 109083915
UniProt ID F6UFU5
mRNA ID XM_002805066
Length 530
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVESHHEYPAMTFYSPAVMNYSSPSNVTNLEGGPGRQTASPNVLWPTPGHLSPLAVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCTSPVTSPSSKRDAHFCAVCSDFASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCASKAKRSGSHAPLVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSNMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLSMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSACSPAEDSKNKEGSQNPQSQ

Gene Information

Entrez Gene ID
574110
Gene Name
estrogen receptor 2 (ER beta)
Gene Symbol
ESR2
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:Ensembl C mitochondrion
GO:0005634 IEA:UniProtKB-SubCell C nucleus
GO:0001046 IEA:Ensembl F core promoter sequence-specific DNA binding
GO:0030284 IEA:InterPro F estrogen receptor activity
GO:0034056 IEA:Ensembl F estrogen response element binding
GO:0004879 IEA:Ensembl F ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005496 IEA:InterPro F steroid binding
GO:0008270 IEA:InterPro F zinc ion binding
GO:0007420 IEA:Ensembl P brain development
GO:0060743 IEA:Ensembl P epithelial cell maturation involved in prostate gland development
GO:0008628 IEA:Ensembl P hormone-mediated apoptotic signaling pathway
GO:0030520 IEA:Ensembl P intracellular estrogen receptor signaling pathway
GO:0060766 IEA:Ensembl P negative regulation of androgen receptor signaling pathway
GO:0050680 IEA:Ensembl P negative regulation of epithelial cell proliferation
GO:0000122 IEA:Ensembl P negative regulation of transcription from RNA polymerase II promoter
GO:0001764 IEA:Ensembl P neuron migration
GO:0001541 IEA:Ensembl P ovarian follicle development
GO:0051091 IEA:Ensembl P positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060740 IEA:Ensembl P prostate gland epithelium morphogenesis
GO:0060065 IEA:Ensembl P uterus development
GO:0060068 IEA:Ensembl P vagina development

KEGG Pathway Links

KEGG Pathway ID Description
ko04915 Estrogen signaling pathway
mcc04915 Estrogen signaling pathway
ko04917 Prolactin signaling pathway
mcc04917 Prolactin signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR028355 Estrogen receptor beta/gamma
IPR021064 Estrogen receptor beta, N-terminal
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR024178 Oestrogen receptor/oestrogen-related receptor
IPR001723 Steroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
estrogen receptor 2 (ER beta)
Protein Entry
F6UFU5_MACMU
UniProt ID
F6UFU5
Species
Rhesus monkey

Comments

Comment Type Description
Similarity Belongs to the nuclear hormone receptor family.
Similarity Belongs to the nuclear hormone receptor family. NR3 subfamily.
Similarity Contains nuclear receptor DNA-binding domain.
Subcellular Location Nucleus

Identical and Related Proteins

Unique RefSeq proteins for LMP014072 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109083915 RefSeq XP_001101433 530 estrogen receptor 2 (ER beta)
297298035 RefSeq XP_002805112 499 estrogen receptor 2 (ER beta)

Identical Sequences to LMP014072 proteins

Reference Database Accession Length Protein Name
GI:388490243 GenBank EHH27955.1 530 hypothetical protein EGK_18278 [Macaca mulatta]
GI:388490243 GenBank AFJ71362.1 530 estrogen receptor beta isoform 1 [Macaca mulatta]

Related Sequences to LMP014072 proteins

Reference Database Accession Length Protein Name
GI:388490243 RefSeq XP_005561513.1 530 PREDICTED: estrogen receptor beta isoform X1 [Macaca fascicularis]
GI:388490243 RefSeq XP_005561514.1 530 PREDICTED: estrogen receptor beta isoform X2 [Macaca fascicularis]