Gene/Proteome Database (LMPD)
LMPD ID
LMP014200
Gene ID
Species
Macaca mulatta (Rhesus monkey)
Gene Name
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Gene Symbol
Alternate Names
trifunctional enzyme subunit alpha, mitochondrial; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit;
Chromosome
13
Map Location
chromosome:13
Proteins
| trifunctional enzyme subunit alpha, mitochondrial | |
|---|---|
| Refseq ID | NP_001252819 |
| Protein GI | 388454076 |
| UniProt ID | F7FRK6 |
| mRNA ID | NM_001265890 |
| Length | 763 |
| Protein sequence is identical to GI:109102275 (mRNA isoform) | |
| Refseq ID | XP_001086472 |
| Protein GI | 109102275 |
| UniProt ID | F7FRK6 |
| mRNA ID | XM_001086472 |
| Length | 763 |
| MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFTEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLSACKTLQEVTQLSQEAQRILEKLEKSPKPVVAAINGSCLGGGLELAISCQYRIATKDRKTVLGVPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRNIRADRAKKMGLVDQLVEPLGPGLKPPEERTMEYLEEVAITFAKGLADKKISPKRNKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLSESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTGLDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSRDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQTIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ | |
| Refseq ID | XP_002799213 |
| Protein GI | 297265590 |
| UniProt ID | F7FRK6 |
| mRNA ID | XM_001086472 |
| Length | 717 |
| MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFTEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLSACKTLQEVTQLSQEAQRILEKLEKSPKPVVAAINGSCLGGGLELAISCQYRNIRADRAKKMGLVDQLVEPLGPGLKPPEERTMEYLEEVAITFAKGLADKKISPKRNKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLSESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTGLDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSRDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQTIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ | |
| Refseq ID | XP_002799214 |
| Protein GI | 297265592 |
| UniProt ID | F7FRK6 |
| mRNA ID | XM_001086472 |
| Length | 573 |
| MVGVPAALDMMLTGRNIRADRAKKMGLVDQLVEPLGPGLKPPEERTMEYLEEVAITFAKGLADKKISPKRNKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLSESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTGLDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSRDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQTIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ | |
Gene Information
Entrez Gene ID
Gene Name
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Gene Symbol
Species
Macaca mulatta
Gene Ontology (GO Annotations)
| GO ID | Source | Type | Description |
|---|---|---|---|
| GO:0016507 | IEA:InterPro | C | mitochondrial fatty acid beta-oxidation multienzyme complex |
| GO:0005743 | IEA:Ensembl | C | mitochondrial inner membrane |
| GO:0042645 | IEA:Ensembl | C | mitochondrial nucleoid |
| GO:0050662 | IEA:InterPro | F | coenzyme binding |
| GO:0004300 | IEA:InterPro | F | enoyl-CoA hydratase activity |
| GO:0016509 | IEA:Ensembl | F | long-chain-3-hydroxyacyl-CoA dehydrogenase activity |
| GO:0006635 | IEA:InterPro | P | fatty acid beta-oxidation |
| GO:0032868 | IEA:Ensembl | P | response to insulin |
KEGG Pathway Links
| KEGG Pathway ID | Description |
|---|---|
| ko01040 | Biosynthesis of unsaturated fatty acids |
| mcc01040 | Biosynthesis of unsaturated fatty acids |
| ko00650 | Butanoate metabolism |
| mcc00650 | Butanoate metabolism |
| ko01200 | Carbon metabolism |
| mcc01200 | Carbon metabolism |
| M00085 | Fatty acid biosynthesis, elongation, mitochondria |
| mcc_M00085 | Fatty acid biosynthesis, elongation, mitochondria |
| ko00071 | Fatty acid degradation |
| mcc00071 | Fatty acid degradation |
| ko00062 | Fatty acid elongation |
| mcc00062 | Fatty acid elongation |
| ko01212 | Fatty acid metabolism |
| mcc01212 | Fatty acid metabolism |
| ko00310 | Lysine degradation |
| mcc00310 | Lysine degradation |
| M00032 | Lysine degradation, lysine => saccharopine => acetoacetyl-CoA |
| mcc_M00032 | Lysine degradation, lysine => saccharopine => acetoacetyl-CoA |
| M00013 | Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA |
| mcc_M00013 | Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA |
| mcc01100 | Metabolic pathways |
| ko00640 | Propanoate metabolism |
| mcc00640 | Propanoate metabolism |
| ko00380 | Tryptophan metabolism |
| mcc00380 | Tryptophan metabolism |
| ko00280 | Valine, leucine and isoleucine degradation |
| mcc00280 | Valine, leucine and isoleucine degradation |
| ko00410 | beta-Alanine metabolism |
| mcc00410 | beta-Alanine metabolism |
| M00087 | beta-Oxidation |
| mcc_M00087 | beta-Oxidation |
Domain Information
InterPro Annotations
| Accession | Description |
|---|---|
| IPR006108 | 3-hydroxyacyl-CoA dehydrogenase, C-terminal |
| IPR006176 | 3-hydroxyacyl-CoA dehydrogenase, NAD binding |
| IPR006180 | 3-hydroxyacyl-CoA dehydrogenase, conserved site |
| IPR008927 | 6-phosphogluconate dehydrogenase, C-terminal-like |
| IPR029045 | ClpP/crotonase-like domain |
| IPR001753 | Crotonase_core_superfam |
| IPR013328 | Dehydrogenase, multihelical |
| IPR018376 | Enoyl-CoA hydratase/isomerase, conserved site |
| IPR012803 | Fatty acid oxidation complex, alpha subunit, mitochondrial |
| IPR016040 | NAD(P)-binding domain |
UniProt Annotations
Entry Information
Gene Name
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Protein Entry
F7FRK6_MACMU
UniProt ID
Species
Rhesus monkey
Identical and Related Proteins
Unique RefSeq proteins for LMP014200 (as displayed in Record Overview)
| Protein GI | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| 109102275 | RefSeq | XP_001086472 | 763 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| 297265590 | RefSeq | XP_002799213 | 717 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
| 297265592 | RefSeq | XP_002799214 | 573 | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit |
Identical Sequences to LMP014200 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|---|---|---|---|
| GI:388454076 | GenBank | AFE66177.1 | 763 | trifunctional enzyme subunit alpha, mitochondrial precursor [Macaca mulatta] |
| GI:388454076 | GenBank | AFH30417.1 | 763 | trifunctional enzyme subunit alpha, mitochondrial precursor [Macaca mulatta] |
| GI:388454076 | GenBank | AFI35193.1 | 763 | trifunctional enzyme subunit alpha, mitochondrial precursor [Macaca mulatta] |
| GI:388454076 | RefSeq | XP_005576406.1 | 763 | PREDICTED: trifunctional enzyme subunit alpha, mitochondrial isoform X1 [Macaca fascicularis] |
Related Sequences to LMP014200 proteins
| Reference | Database | Accession | Length | Protein Name |
|---|