Gene/Proteome Database (LMPD)

LMPD ID
LMP014207
Gene ID
704464
Species
Macaca mulatta (Rhesus monkey)
Gene Name
hexosaminidase B (beta polypeptide)
Gene Symbol
HEXB
Alternate Names
beta-hexosaminidase subunit beta; beta-hexosaminidase subunit beta preproprotein;
Chromosome
6
Map Location
chromosome:6
EC Number
3.2.1.52

Proteins

beta-hexosaminidase subunit beta
Refseq ID NP_001253386
Protein GI 388454685
UniProt ID F7FNG8
mRNA ID NM_001266457
Length 556
Protein sequence is identical to GI:109077594 (mRNA isoform)
Refseq ID XP_001103139
Protein GI 109077594
UniProt ID F7FNG8
mRNA ID XM_001103139
Length 556
MELCGLGLPRPPMLLALLLATLLAAMLALLTQVALVVQVAEATRAPGVSAARGPALWPLPLSVKMTPNLLHLAPENFYISHSPNSTAGPSCTLLEEAFRRYHSYIFGFYKWDHEPAKSQATAQLQQLLVSITLQSECDAFPNISSDESYTLLVKEPVAVLKANRVWGALRGLETFSQLVYQDSCGTFTINESTIIDSPRFPHRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHWHIVDDQSFPYQSIAFPELSNKGSYSLSHVYTPNDVRMVIEYARLRGIRVLPEFDTPGHTLSWGKGQKDLLTPCYSRQNKLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWESNPKIQDFMKQKGFGKDFKKLESFYIQKVLDIIATINKGSIVWQEVFDDKVKLAPGTIVEVWKDNAYPEELSKVTASGFPVILSAPWYLDLISYGQDWRKYYKVEPLDFGGTREQKQLFIGGEACLWGEYVDATNLTPRLWPRASAVGERLWSSKDVRDMDGAYDRLTRHRCRMVERGIAAQPLYAGYCNHENV

Gene Information

Entrez Gene ID
704464
Gene Name
hexosaminidase B (beta polypeptide)
Gene Symbol
HEXB
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0001669 IEA:Ensembl C acrosomal vesicle
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005764 IEA:Ensembl C lysosome
GO:0016020 IEA:Ensembl C membrane
GO:0004563 IEA:UniProtKB-EC F beta-N-acetylhexosaminidase activity
GO:0043615 IEA:Ensembl P astrocyte cell migration
GO:0006874 IEA:Ensembl P cellular calcium ion homeostasis
GO:0044267 IEA:Ensembl P cellular protein metabolic process
GO:0006689 IEA:Ensembl P ganglioside catabolic process
GO:0030203 IEA:Ensembl P glycosaminoglycan metabolic process
GO:0019915 IEA:Ensembl P lipid storage
GO:0007626 IEA:Ensembl P locomotory behavior
GO:0007040 IEA:Ensembl P lysosome organization
GO:0008049 IEA:Ensembl P male courtship behavior
GO:0042552 IEA:Ensembl P myelination
GO:0050885 IEA:Ensembl P neuromuscular process controlling balance
GO:0009313 IEA:Ensembl P oligosaccharide catabolic process
GO:0048477 IEA:Ensembl P oogenesis
GO:0007341 IEA:Ensembl P penetration of zona pellucida
GO:0008654 IEA:Ensembl P phospholipid biosynthetic process
GO:0045944 IEA:Ensembl P positive regulation of transcription from RNA polymerase II promoter
GO:0008360 IEA:Ensembl P regulation of cell shape
GO:0007605 IEA:Ensembl P sensory perception of sound
GO:0001501 IEA:Ensembl P skeletal system development

KEGG Pathway Links

KEGG Pathway ID Description
ko00520 Amino sugar and nucleotide sugar metabolism
mcc00520 Amino sugar and nucleotide sugar metabolism
ko00531 Glycosaminoglycan degradation
mcc00531 Glycosaminoglycan degradation
ko00604 Glycosphingolipid biosynthesis - ganglio series
mcc00604 Glycosphingolipid biosynthesis - ganglio series
ko00603 Glycosphingolipid biosynthesis - globo series
mcc00603 Glycosphingolipid biosynthesis - globo series
M00079 Keratan sulfate degradation
mcc_M00079 Keratan sulfate degradation
ko04142 Lysosome
mcc04142 Lysosome
mcc01100 Metabolic pathways
ko00511 Other glycan degradation
mcc00511 Other glycan degradation

Domain Information

InterPro Annotations

Accession Description
IPR029019 Beta-hexosaminidase, eukaryotic type, N-terminal
IPR025705 Beta_hexosaminidase_sua/sub
IPR029018 Chitobiase/beta-hexosaminidase domain 2-like
IPR015883 Glycoside hydrolase family 20, catalytic core
IPR017853 Glycoside hydrolase superfamily
IPR013781 Glycoside hydrolase, catalytic domain

UniProt Annotations

Entry Information

Gene Name
hexosaminidase B (beta polypeptide)
Protein Entry
F7FNG8_MACMU
UniProt ID
F7FNG8
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity Hydrolysis of terminal non-reducing N-acetyl- D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
Similarity Belongs to the glycosyl hydrolase 20 family.

Identical and Related Proteins

Unique RefSeq proteins for LMP014207 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109077594 RefSeq XP_001103139 556 hexosaminidase B (beta polypeptide)

Identical Sequences to LMP014207 proteins

Reference Database Accession Length Protein Name
GI:388454685 GenBank AFE77998.1 556 beta-hexosaminidase subunit beta preproprotein [Macaca mulatta]
GI:388454685 GenBank AFH32165.1 556 beta-hexosaminidase subunit beta preproprotein [Macaca mulatta]
GI:388454685 GenBank AFI36971.1 556 beta-hexosaminidase subunit beta preproprotein [Macaca mulatta]
GI:388454685 RefSeq XP_005557204.1 556 PREDICTED: beta-hexosaminidase subunit beta [Macaca fascicularis]

Related Sequences to LMP014207 proteins

Reference Database Accession Length Protein Name
GI:388454685 GenBank EHH26577.1 556 Beta-hexosaminidase subunit beta [Macaca mulatta]