Gene/Proteome Database (LMPD)

LMPD ID
LMP014217
Gene ID
702553
Species
Macaca mulatta (Rhesus monkey)
Gene Name
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Gene Symbol
HMGCS1
Alternate Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble);
Chromosome
6
Map Location
chromosome:6

Proteins

hydroxymethylglutaryl-CoA synthase, cytoplasmic
Refseq ID NP_001247798
Protein GI 386780922
UniProt ID F7HQ90
mRNA ID NM_001260869
Length 520
Protein sequence is identical to GI:297294225 (mRNA isoform)
Refseq ID XP_002804403
Protein GI 297294225
UniProt ID F7HQ90
mRNA ID XM_001090857
Length 520
MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQNLMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIRAQWQKEGNDKDFTLNDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDVEKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSYGSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTCVAPDVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRPTPNDDTLDEGVGLVHSNTATEHIPSPAKKVPRLPATAAEPEAAVISNGEH
Refseq ID XP_001090857
Protein GI 297294227
UniProt ID F7HQ90
mRNA ID XM_001090857
Length 520
Protein sequence is identical to GI:297294225 (mRNA isoform)

Gene Information

Entrez Gene ID
702553
Gene Name
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Gene Symbol
HMGCS1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:Ensembl C cytoplasm
GO:0005634 IEA:Ensembl C nucleus
GO:0005886 IEA:Ensembl C plasma membrane
GO:0004421 IEA:InterPro F hydroxymethylglutaryl-CoA synthase activity
GO:0008299 IEA:InterPro P isoprenoid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00650 Butanoate metabolism
mcc00650 Butanoate metabolism
M00095 C5 isoprenoid biosynthesis, mevalonate pathway
mcc_M00095 C5 isoprenoid biosynthesis, mevalonate pathway
mcc01100 Metabolic pathways
ko00072 Synthesis and degradation of ketone bodies
mcc00072 Synthesis and degradation of ketone bodies
ko00900 Terpenoid backbone biosynthesis
mcc00900 Terpenoid backbone biosynthesis
ko00280 Valine, leucine and isoleucine degradation
mcc00280 Valine, leucine and isoleucine degradation

Domain Information

InterPro Annotations

Accession Description
IPR010122 Hydroxymethylglutaryl-CoA synthase, eukaryotic
IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain
IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal
IPR000590 Hydroxymethylglutaryl-coenzyme A synthase, active site
IPR016039 Thiolase-like
IPR016038 Thiolase-like, subgroup

UniProt Annotations

Entry Information

Gene Name
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Protein Entry
F7HQ90_MACMU
UniProt ID
F7HQ90
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014217 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
297294225 RefSeq XP_002804403 520 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

Identical Sequences to LMP014217 proteins

Reference Database Accession Length Protein Name
GI:386780922 RefSeq XP_003899683.1 520 PREDICTED: hydroxymethylglutaryl-CoA synthase, cytoplasmic [Papio anubis]
GI:386780922 RefSeq XP_003899684.1 520 PREDICTED: hydroxymethylglutaryl-CoA synthase, cytoplasmic [Papio anubis]
GI:386780922 RefSeq XP_005556893.1 520 PREDICTED: hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X2 [Macaca fascicularis]
GI:386780922 RefSeq XP_005556894.1 520 PREDICTED: hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X3 [Macaca fascicularis]

Related Sequences to LMP014217 proteins

Reference Database Accession Length Protein Name
GI:386780922 GenBank EHH25426.1 520 Hydroxymethylglutaryl-CoA synthase, cytoplasmic [Macaca mulatta]
GI:386780922 GenBank EHH54234.1 520 Hydroxymethylglutaryl-CoA synthase, cytoplasmic [Macaca fascicularis]