Gene/Proteome Database (LMPD)

LMPD ID
LMP014265
Gene ID
721222
Species
Macaca mulatta (Rhesus monkey)
Gene Name
inositol polyphosphate-5-phosphatase K
Gene Symbol
INPP5K
Alternate Names
inositol polyphosphate 5-phosphatase K;
Chromosome
16
Map Location
chromosome:16

Proteins

inositol polyphosphate 5-phosphatase K
Refseq ID NP_001247575
Protein GI 386781117
UniProt ID F7BZ97
mRNA ID NM_001260646
Length 448
Protein sequence is identical to GI:297271542 (mRNA isoform)
Refseq ID XP_002800283
Protein GI 297271546
UniProt ID F7BZ97
mRNA ID XM_001117306
Length 356
MQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYSGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPQAGPDTPRLPAPDFSLSLRSYSSHMVYSISDHKPVTGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTLDFPSSPWDWIGLYKVGLRDINDYVSYAWVGDSQVSCSDNLNQVYIDISNIPATEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPLGEAQPQI
Refseq ID XP_001117306
Protein GI 297271542
UniProt ID F7BZ97
mRNA ID XM_001117306
Length 448
MSSRKLSGPKGRRLSIHVVTWNVASAAPPLDLSDLLQLNNQNLNLDIYVIGLQELNSGIISLLSDAAFNDSWSSFLMDVLSPLSFVKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYSGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPQAGPDTPRLPAPDFSLSLRSYSSHMVYSISDHKPVTGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTLDFPSSPWDWIGLYKVGLRDINDYVSYAWVGDSQVSCSDNLNQVYIDISNIPATEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPLGEAQPQI
Refseq ID XP_002800282
Protein GI 297271544
UniProt ID F7BZ97
mRNA ID XM_001117306
Length 449
MSSRKLSGPKGRRLSSIHVVTWNVASAAPPLDLSDLLQLNNQNLNLDIYVIGLQELNSGIISLLSDAAFNDSWSSFLMDVLSPLSFVKVSHVRMQGILLLVFAKYQHLPYIQILSTKSTPTGLFGYWGNKGGVNICLKLYGYYVSIINCHLPPHISNNYQRLEHFDRILEMQNCEGRDIPNILDHDLIIWFGDMNFRIEDFGLHFVRESIKNRCYSGLWEKDQLSIAKKHDPLLREFQEGRLLFPPTYKFDRNSNDYDTSEKKRKPAWTDRILWRLKRQPQAGPDTPRLPAPDFSLSLRSYSSHMVYSISDHKPVTGTFDLELKPLVSAPLIVLMPEDLWTVENDMMVSYSSTLDFPSSPWDWIGLYKVGLRDINDYVSYAWVGDSQVSCSDNLNQVYIDISNIPATEDEFLLCYYSNSLRSVVGISRPFQIPPGSLREDPLGEAQPQI

Gene Information

Entrez Gene ID
721222
Gene Name
inositol polyphosphate-5-phosphatase K
Gene Symbol
INPP5K
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 ISS:UniProtKB C cytoplasm
GO:0005829 ISS:UniProtKB C cytosol
GO:0005783 ISS:UniProtKB C endoplasmic reticulum
GO:0016020 ISS:UniProtKB C membrane
GO:0043005 ISS:UniProtKB C neuron projection
GO:0005634 ISS:UniProtKB C nucleus
GO:0048471 ISS:UniProtKB C perinuclear region of cytoplasm
GO:0005886 ISS:UniProtKB C plasma membrane
GO:0001726 ISS:UniProtKB C ruffle
GO:0032587 ISS:UniProtKB C ruffle membrane
GO:0005802 ISS:UniProtKB C trans-Golgi network
GO:0016312 ISS:UniProtKB F inositol bisphosphate phosphatase activity
GO:0046030 IEA:Ensembl F inositol trisphosphate phosphatase activity
GO:0034485 ISS:UniProtKB F phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
GO:0034595 ISS:UniProtKB F phosphatidylinositol phosphate 5-phosphatase activity
GO:0034594 ISS:UniProtKB F phosphatidylinositol trisphosphate phosphatase activity
GO:0005000 ISS:UniProtKB F vasopressin receptor activity
GO:0071320 ISS:UniProtKB P cellular response to cAMP
GO:0071364 ISS:UniProtKB P cellular response to epidermal growth factor stimulus
GO:0032870 ISS:UniProtKB P cellular response to hormone stimulus
GO:0032869 ISS:UniProtKB P cellular response to insulin stimulus
GO:0071356 ISS:UniProtKB P cellular response to tumor necrosis factor
GO:0016311 ISS:UniProtKB P dephosphorylation
GO:0042593 ISS:UniProtKB P glucose homeostasis
GO:0007186 ISS:UniProtKB P G-protein coupled receptor signaling pathway
GO:0046855 IEA:Ensembl P inositol phosphate dephosphorylation
GO:0001701 IEA:Ensembl P in utero embryonic development
GO:0043922 ISS:UniProtKB P negative regulation by host of viral transcription
GO:0051926 ISS:UniProtKB P negative regulation of calcium ion transport
GO:0035305 ISS:UniProtKB P negative regulation of dephosphorylation
GO:0010829 ISS:UniProtKB P negative regulation of glucose transport
GO:0045719 ISS:UniProtKB P negative regulation of glycogen biosynthetic process
GO:2000466 ISS:UniProtKB P negative regulation of glycogen (starch) synthase activity
GO:0046627 ISS:UniProtKB P negative regulation of insulin receptor signaling pathway
GO:0043407 ISS:UniProtKB P negative regulation of MAP kinase activity
GO:0033137 ISS:UniProtKB P negative regulation of peptidyl-serine phosphorylation
GO:0010801 ISS:UniProtKB P negative regulation of peptidyl-threonine phosphorylation
GO:0006469 ISS:UniProtKB P negative regulation of protein kinase activity
GO:0051898 ISS:UniProtKB P negative regulation of protein kinase B signaling
GO:0001933 ISS:UniProtKB P negative regulation of protein phosphorylation
GO:0090315 ISS:UniProtKB P negative regulation of protein targeting to membrane
GO:0045869 ISS:UniProtKB P negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0051497 ISS:UniProtKB P negative regulation of stress fiber assembly
GO:0045892 ISS:UniProtKB P negative regulation of transcription, DNA-templated
GO:0046856 ISS:UniProtKB P phosphatidylinositol dephosphorylation
GO:2001153 ISS:UniProtKB P positive regulation of renal water transport
GO:0045893 ISS:UniProtKB P positive regulation of transcription, DNA-templated
GO:0035810 ISS:UniProtKB P positive regulation of urine volume
GO:0072661 ISS:UniProtKB P protein targeting to plasma membrane
GO:0005979 ISS:UniProtKB P regulation of glycogen biosynthetic process
GO:0097178 ISS:UniProtKB P ruffle assembly

KEGG Pathway Links

KEGG Pathway ID Description
ko00562 Inositol phosphate metabolism
mcc00562 Inositol phosphate metabolism
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
mcc_M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
mcc01100 Metabolic pathways
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system

Domain Information

InterPro Annotations

Accession Description
IPR005135 Endonuclease/exonuclease/phosphatase
IPR000300 Inositol polyphosphate-related phosphatase

UniProt Annotations

Entry Information

Gene Name
inositol polyphosphate-5-phosphatase K
Protein Entry
F7BZ97_MACMU
UniProt ID
F7BZ97
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014265 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
297271544 RefSeq XP_002800282 449 inositol polyphosphate-5-phosphatase K
297271542 RefSeq XP_001117306 448 inositol polyphosphate-5-phosphatase K
297271546 RefSeq XP_002800283 356 inositol polyphosphate-5-phosphatase K

Identical Sequences to LMP014265 proteins

Reference Database Accession Length Protein Name
GI:386781117 GenBank AFH28470.1 448 inositol polyphosphate 5-phosphatase K isoform 1 [Macaca mulatta]
GI:386781117 GenBank AFI34765.1 448 inositol polyphosphate 5-phosphatase K isoform 1 [Macaca mulatta]
GI:386781117 RefSeq XP_003912101.1 448 PREDICTED: inositol polyphosphate 5-phosphatase K isoform X2 [Papio anubis]
GI:386781117 RefSeq XP_005582493.1 448 PREDICTED: inositol polyphosphate 5-phosphatase K isoform X1 [Macaca fascicularis]

Related Sequences to LMP014265 proteins

Reference Database Accession Length Protein Name
GI:386781117 GenBank EHH24336.1 448 Inositol polyphosphate 5-phosphatase K [Macaca mulatta]
GI:386781117 GenBank AFE66877.1 448 inositol polyphosphate 5-phosphatase K isoform 1 [Macaca mulatta]