Gene/Proteome Database (LMPD)

LMPD ID
LMP014425
Gene ID
719210
Species
Macaca mulatta (Rhesus monkey)
Gene Name
nuclear receptor subfamily 1, group H, member 2
Gene Symbol
NR1H2
Alternate Names
oxysterols receptor LXR-beta;
Chromosome
19
Map Location
chromosome:19

Proteins

oxysterols receptor LXR-beta
Refseq ID NP_001181626
Protein GI 302565068
UniProt ID F7F982
mRNA ID NM_001194697
Length 461
Protein sequence is identical to GI:109125652 (mRNA isoform)
Refseq ID XP_001115995
Protein GI 297277685
UniProt ID F6ZNM1
mRNA ID XM_001116006
Length 480
MIKGEWALPRKSRLLRDPTMSSPTTSSLDTPLLGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEAGSACSVDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQQSQSQSQSPAGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Refseq ID XP_001115983
Protein GI 109125654
UniProt ID F7F982
mRNA ID XM_001116006
Length 417
MSSPTTSSLDTPLLGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEAGSACSVDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQQSQSQSQSPAGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
Refseq ID XP_001116006
Protein GI 109125652
UniProt ID F7F982
mRNA ID XM_001116006
Length 461
MSSPTTSSLDTPLLGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEAGSACSVDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQQSQSQSQSPAGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Gene Information

Entrez Gene ID
719210
Gene Name
nuclear receptor subfamily 1, group H, member 2
Gene Symbol
NR1H2
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:Ensembl C cytoplasm
GO:0005634 IEA:UniProtKB-KW C nucleus
GO:0000978 IEA:Ensembl F RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA:Ensembl F RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0004879 IEA:Ensembl F ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003707 IEA:InterPro F steroid hormone receptor activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0044255 IEA:Ensembl P cellular lipid metabolic process
GO:0010887 IEA:Ensembl P negative regulation of cholesterol storage
GO:0032369 IEA:Ensembl P negative regulation of lipid transport
GO:0048550 IEA:Ensembl P negative regulation of pinocytosis
GO:0045892 IEA:Ensembl P negative regulation of transcription, DNA-templated
GO:0032270 IEA:Ensembl P positive regulation of cellular protein metabolic process
GO:0010875 IEA:Ensembl P positive regulation of cholesterol efflux
GO:0045723 IEA:Ensembl P positive regulation of fatty acid biosynthetic process
GO:0051006 IEA:Ensembl P positive regulation of lipoprotein lipase activity
GO:0010867 IEA:Ensembl P positive regulation of triglyceride biosynthetic process

Domain Information

InterPro Annotations

Accession Description
IPR023257 Liver X receptor
IPR008946 Nuclear hormone receptor, ligand-binding
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001723 Steroid hormone receptor
IPR013088 Zinc finger, NHR/GATA-type
IPR001628 Zinc finger, nuclear hormone receptor-type

UniProt Annotations

Entry Information

Gene Name
nuclear receptor subfamily 1, group H, member 2
UniProt ID
F7F982
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Belongs to the nuclear hormone receptor family.
Similarity Contains nuclear receptor DNA-binding domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014425 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
297277685 RefSeq XP_001115995 480 nuclear receptor subfamily 1, group H, member 2
109125652 RefSeq XP_001116006 461 nuclear receptor subfamily 1, group H, member 2
109125654 RefSeq XP_001115983 417 nuclear receptor subfamily 1, group H, member 2

Identical Sequences to LMP014425 proteins

Reference Database Accession Length Protein Name
GI:302565068 GenBank AFH29156.1 461 oxysterols receptor LXR-beta [Macaca mulatta]
GI:302565068 GenBank AFI35824.1 461 oxysterols receptor LXR-beta [Macaca mulatta]
GI:302565068 RefSeq XP_005590061.1 461 PREDICTED: oxysterols receptor LXR-beta isoform X1 [Macaca fascicularis]
GI:302565068 RefSeq XP_007995834.1 461 PREDICTED: oxysterols receptor LXR-beta isoform X1 [Chlorocebus sabaeus]

Related Sequences to LMP014425 proteins

Reference Database Accession Length Protein Name
GI:302565068 GenBank EHH30292.1 461 hypothetical protein EGK_10924 [Macaca mulatta]