Gene/Proteome Database (LMPD)

LMPD ID
LMP014470
Gene ID
703382
Species
Macaca mulatta (Rhesus monkey)
Gene Name
3-oxoacyl-ACP synthase, mitochondrial
Gene Symbol
OXSM
Alternate Names
3-oxoacyl-ACP synthase, mitochondrial;
Chromosome
2
Map Location
chromosome:2
EC Number
2.3.1.41

Proteins

Refseq ID XP_001091681
Protein GI 109052601
UniProt ID F6W670
mRNA ID XM_001091681
Length 460
MSNCLQNFLKITSTRLLCSRLCQQVTRSKRKFFGTEPINRLHRRVVITGIGLVTPLGVGTHLVWDRLIAGKSGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNRVSPFFVPKILINMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIARGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAAEAAFTTLACYYQKLPPTLNLDCTEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGM

Gene Information

Entrez Gene ID
703382
Gene Name
3-oxoacyl-ACP synthase, mitochondrial
Gene Symbol
OXSM
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IEA:UniProtKB-SubCell C mitochondrion
GO:0004315 IEA:UniProtKB-EC F 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0006637 IEA:Ensembl P acyl-CoA metabolic process
GO:0051792 IEA:Ensembl P medium-chain fatty acid biosynthetic process
GO:0051790 IEA:Ensembl P short-chain fatty acid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ko00780 Biotin metabolism
mcc00780 Biotin metabolism
ko00061 Fatty acid biosynthesis
mcc00061 Fatty acid biosynthesis
M00083 Fatty acid biosynthesis, elongation
mcc_M00083 Fatty acid biosynthesis, elongation
ko01212 Fatty acid metabolism
mcc01212 Fatty acid metabolism
mcc01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2
IPR014031 Beta-ketoacyl synthase, C-terminal
IPR014030 Beta-ketoacyl synthase, N-terminal
IPR018201 Beta-ketoacyl synthase, active site
IPR016039 Thiolase-like
IPR016038 Thiolase-like, subgroup

UniProt Annotations

Entry Information

Gene Name
3-oxoacyl-ACP synthase, mitochondrial
Protein Entry
F6W670_MACMU
UniProt ID
F6W670
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity Acyl-[acyl-carrier-protein] + malonyl-[acyl- carrier-protein] = 3-oxoacyl-[acyl-carrier-protein] + CO(2) + [acyl-carrier-protein].
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Function May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
Pathway Lipid metabolism; fatty acid biosynthesis.
Similarity Belongs to the beta-ketoacyl-ACP synthases family.
Subcellular Location Mitochondrion

Identical and Related Proteins

Unique RefSeq proteins for LMP014470 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109052601 RefSeq XP_001091681 460 3-oxoacyl-ACP synthase, mitochondrial

Identical Sequences to LMP014470 proteins

Reference Database Accession Length Protein Name
GI:109052601 RefSeq XP_005545683.1 460 PREDICTED: 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial isoform X1 [Macaca fascicularis]

Related Sequences to LMP014470 proteins

Reference Database Accession Length Protein Name
GI:109052601 GenBank EHH51719.1 460 hypothetical protein EGM_11151 [Macaca fascicularis]
GI:109052601 RefSeq XP_003895234.1 460 PREDICTED: 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial isoform X1 [Papio anubis]
GI:109052601 RefSeq XP_008007490.1 460 PREDICTED: 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial [Chlorocebus sabaeus]