Gene/Proteome Database (LMPD)

LMPD ID
LMP014503
Gene ID
711029
Species
Macaca mulatta (Rhesus monkey)
Gene Name
protein disulfide isomerase family A, member 3
Gene Symbol
PDIA3
Synonyms
GRP58;
Alternate Names
protein disulfide-isomerase A3; glucose regulated protein, 58kDa;
Chromosome
7
Map Location
chromosome:7
EC Number
5.3.4.1

Proteins

protein disulfide-isomerase A3 precursor
Refseq ID NP_001182645
Protein GI 307611977
UniProt ID F7G3A7
mRNA ID NM_001195716
Length 505
Protein sequence is identical to GI:109080868 (mRNA isoform)
sig_peptide: 1..24 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2535 peptide sequence: MRLRRLALFPGVALLLAAARLAAA
Refseq ID XP_001109061
Protein GI 109080868
UniProt ID F7G3A7
mRNA ID XM_001109061
Length 505
MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRVSDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASVVGFFDDLFSEAHSEFLKAASNLRDNYRFAHTNVKSLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
sig_peptide: 1..24 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2535 peptide sequence: MRLRRLALFPGVALLLAAARLAAA

Gene Information

Entrez Gene ID
711029
Gene Name
protein disulfide isomerase family A, member 3
Gene Symbol
PDIA3
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0009986 IEA:Ensembl C cell surface
GO:0005783 IEA:Ensembl C endoplasmic reticulum
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005634 IEA:Ensembl C nucleus
GO:0044822 IEA:Ensembl F poly(A) RNA binding
GO:0003756 IEA:UniProtKB-EC F protein disulfide isomerase activity
GO:0045454 IEA:InterPro P cell redox homeostasis
GO:2001238 IEA:Ensembl P positive regulation of extrinsic apoptotic signaling pathway

KEGG Pathway Links

KEGG Pathway ID Description
ko04612 Antigen processing and presentation
mcc04612 Antigen processing and presentation
ko04141 Protein processing in endoplasmic reticulum
mcc04141 Protein processing in endoplasmic reticulum

Domain Information

InterPro Annotations

Accession Description
IPR005788 Disulphide_isomerase
IPR005792 Protein disulphide isomerase
IPR017937 Thioredoxin, conserved site
IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin_domain

UniProt Annotations

Entry Information

Gene Name
protein disulfide isomerase family A, member 3
Protein Entry
F7G3A7_MACMU
UniProt ID
F7G3A7
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity Catalyzes the rearrangement of -S-S- bonds in proteins.
Similarity Belongs to the protein disulfide isomerase family.
Similarity Contains 2 thioredoxin domains.

Identical and Related Proteins

Unique RefSeq proteins for LMP014503 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109080868 RefSeq XP_001109061 505 protein disulfide isomerase family A, member 3

Identical Sequences to LMP014503 proteins

Reference Database Accession Length Protein Name
GI:307611977 GenBank AFH28815.1 505 protein disulfide-isomerase A3 precursor [Macaca mulatta]
GI:307611977 RefSeq XP_005559435.1 505 PREDICTED: protein disulfide-isomerase A3 isoform X1 [Macaca fascicularis]
GI:307611977 RefSeq XP_008015011.1 505 PREDICTED: protein disulfide-isomerase A3 [Chlorocebus sabaeus]
GI:307611977 RefSeq XP_010383550.1 505 PREDICTED: protein disulfide-isomerase A3 [Rhinopithecus roxellana]

Related Sequences to LMP014503 proteins

Reference Database Accession Length Protein Name
GI:307611977 GenBank ABY40815.1 505 protein disulfide isomerase family A, member 3 (predicted) [Papio anubis]
GI:307611977 RefSeq NP_001162437.1 505 protein disulfide-isomerase A3 precursor [Papio anubis]
GI:307611977 SwissProt Q4VIT4.1 505 RecName: Full=Protein disulfide-isomerase A3; AltName: Full=Endoplasmic reticulum resident protein 57; Short=ER protein 57; Short=ERp57; AltName: Full=Endoplasmic reticulum resident protein 60; Short=ER protein 60; Short=ERp60; Flags: Precursor [Chlorocebus aethiops]