Gene/Proteome Database (LMPD)

LMPD ID
LMP014541
Gene ID
706003
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phosphatidylinositol binding clathrin assembly protein
Gene Symbol
PICALM
Alternate Names
phosphatidylinositol-binding clathrin assembly protein;
Chromosome
14
Map Location
chromosome:14

Proteins

phosphatidylinositol-binding clathrin assembly protein
Refseq ID NP_001253428
Protein GI 388452570
UniProt ID H9ZE41
mRNA ID NM_001266499
Length 652
Protein sequence is identical to GI:297268896 (mRNA isoform)
Refseq ID XP_002799775
Protein GI 297268896
UniProt ID H9ZE41
mRNA ID XM_002799729
Length 652
MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM

Gene Information

Entrez Gene ID
706003
Gene Name
phosphatidylinositol binding clathrin assembly protein
Gene Symbol
PICALM
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0030122 IEA:Ensembl C AP-2 adaptor complex
GO:0097418 IEA:Ensembl C neurofibrillary tangle
GO:0043025 IEA:Ensembl C neuronal cell body
GO:0005634 IEA:Ensembl C nucleus
GO:0048471 IEA:Ensembl C perinuclear region of cytoplasm
GO:0005545 IEA:InterPro F 1-phosphatidylinositol binding
GO:0007409 IEA:Ensembl P axonogenesis
GO:0035459 IEA:Ensembl P cargo loading into vesicle
GO:0008283 IEA:Ensembl P cell proliferation
GO:0048268 IEA:InterPro P clathrin coat assembly
GO:0072583 IEA:Ensembl P clathrin-mediated endocytosis
GO:0048813 IEA:Ensembl P dendrite morphogenesis
GO:0016197 IEA:Ensembl P endosomal transport
GO:0030097 IEA:Ensembl P hemopoiesis
GO:0055072 IEA:Ensembl P iron ion homeostasis
GO:0097459 IEA:Ensembl P iron ion import into cell
GO:0010629 IEA:Ensembl P negative regulation of gene expression
GO:1902963 IEA:Ensembl P negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
GO:0048261 IEA:Ensembl P negative regulation of receptor-mediated endocytosis
GO:1902961 IEA:Ensembl P positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902004 IEA:Ensembl P positive regulation of beta-amyloid formation
GO:1901216 IEA:Ensembl P positive regulation of neuron death
GO:0045893 IEA:Ensembl P positive regulation of transcription, DNA-templated
GO:0031623 IEA:Ensembl P receptor internalization
GO:0032880 IEA:Ensembl P regulation of protein localization
GO:0016188 IEA:Ensembl P synaptic vesicle maturation

Domain Information

InterPro Annotations

Accession Description
IPR011417 AP180 N-terminal homology (ANTH) domain
IPR008942 ENTH_VHS
IPR013809 Epsin-like_N
IPR014712 Phosphoinositide-binding clathrin adaptor, domain 2

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol binding clathrin assembly protein
Protein Entry
H9ZE41_MACMU
UniProt ID
H9ZE41
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014541 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
297268896 RefSeq XP_002799775 652 phosphatidylinositol binding clathrin assembly protein

Identical Sequences to LMP014541 proteins

Reference Database Accession Length Protein Name
GI:388452570 RefSeq XP_003910555.1 652 PREDICTED: phosphatidylinositol-binding clathrin assembly protein isoform X11 [Papio anubis]
GI:388452570 RefSeq XP_005579329.1 652 PREDICTED: phosphatidylinositol-binding clathrin assembly protein isoform X7 [Macaca fascicularis]
GI:388452570 RefSeq XP_008018614.1 652 PREDICTED: phosphatidylinositol-binding clathrin assembly protein isoform X6 [Chlorocebus sabaeus]
GI:388452570 RefSeq XP_010354315.1 652 PREDICTED: phosphatidylinositol-binding clathrin assembly protein isoform X7 [Rhinopithecus roxellana]

Related Sequences to LMP014541 proteins

Reference Database Accession Length Protein Name
GI:388452570 GenBank AFH34207.1 652 phosphatidylinositol-binding clathrin assembly protein isoform 1 [Macaca mulatta]
GI:388452570 RefSeq XP_003254625.1 652 PREDICTED: phosphatidylinositol-binding clathrin assembly protein isoform 2 [Nomascus leucogenys]