Gene/Proteome Database (LMPD)

LMPD ID
LMP014562
Gene ID
693918
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phosphatidylinositol 3-kinase, catalytic subunit type 3
Gene Symbol
PIK3C3
Alternate Names
phosphatidylinositol 3-kinase, catalytic subunit type 3; phosphoinositide-3-kinase, class 3;
Chromosome
18
Map Location
chromosome:18
EC Number
2.7.1.137

Proteins

Refseq ID XP_001082892
Protein GI 109122041
UniProt ID F7GT63
mRNA ID XM_001082892
Length 887
MGEAEKFHYLYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTVWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENLSNSGINSAEIDSSQIITSPLPPVSSPPPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
Refseq ID XP_002800970
Protein GI 297275232
UniProt ID F7GT63
mRNA ID XM_001082892
Length 824
MGEAEKFHYLYSCDLDINVQLKIWNEWLKLPVKYPDLPRNAQVALTVWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENLSNSGINSAEIDSSQIITSPLPPVSSPPPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK

Gene Information

Entrez Gene ID
693918
Gene Name
phosphatidylinositol 3-kinase, catalytic subunit type 3
Gene Symbol
PIK3C3
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005770 IEA:Ensembl C late endosome
GO:0016020 IEA:Ensembl C membrane
GO:0030496 IEA:Ensembl C midbody
GO:0045335 IEA:Ensembl C phagocytic vesicle
GO:0016303 IEA:UniProtKB-EC F 1-phosphatidylinositol-3-kinase activity
GO:0005524 IEA:UniProtKB-KW F ATP binding
GO:0004672 IEA:Ensembl F protein kinase activity
GO:0000910 IEA:Ensembl P cytokinesis
GO:0045022 IEA:Ensembl P early endosome to late endosome transport
GO:0048015 IEA:InterPro P phosphatidylinositol-mediated signaling

KEGG Pathway Links

KEGG Pathway ID Description
ko00562 Inositol phosphate metabolism
mcc00562 Inositol phosphate metabolism
mcc01100 Metabolic pathways
ko04145 Phagosome
mcc04145 Phagosome
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
ko04140 Regulation of autophagy
mcc04140 Regulation of autophagy
ko05152 Tuberculosis
mcc05152 Tuberculosis

Domain Information

InterPro Annotations

Accession Description
IPR016024 Armadillo-type fold
IPR000008 C2 domain
IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain
IPR002420 Phosphatidylinositol 3-kinase, C2 domain
IPR008290 Phosphatidylinositol 3-kinase, Vps34 type
IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
IPR015433 Phosphatidylinositol Kinase
IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain
IPR011009 Protein kinase-like domain

UniProt Annotations

Entry Information

Gene Name
phosphatidylinositol 3-kinase, catalytic subunit type 3
Protein Entry
F7GT63_MACMU
UniProt ID
F7GT63
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Belongs to the PI3/PI4-kinase family.
Similarity Contains PI3K/PI4K domain.
Similarity Contains PIK helical domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014562 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109122041 RefSeq XP_001082892 887 phosphatidylinositol 3-kinase, catalytic subunit type 3
297275232 RefSeq XP_002800970 824 phosphatidylinositol 3-kinase, catalytic subunit type 3

Identical Sequences to LMP014562 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP014562 proteins

Reference Database Accession Length Protein Name
GI:297275232 GenBank AFE64002.1 887 phosphatidylinositol 3-kinase catalytic subunit type 3 [Macaca mulatta]
GI:297275232 GenBank AFH27474.1 887 phosphatidylinositol 3-kinase catalytic subunit type 3 [Macaca mulatta]
GI:297275232 GenBank AFI35288.1 887 phosphatidylinositol 3-kinase catalytic subunit type 3 [Macaca mulatta]
GI:297275232 RefSeq XP_002828228.1 824 PREDICTED: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2 [Pongo abelii]