Gene/Proteome Database (LMPD)

LMPD ID
LMP014573
Gene ID
710115
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phosphoinositide kinase, FYVE finger containing
Gene Symbol
PIKFYVE
Alternate Names
phosphoinositide kinase, FYVE finger containing;
Chromosome
12
Map Location
chromosome:12

Proteins

Refseq ID XP_001108540
Protein GI 109100777
UniProt ID F6UUQ5
mRNA ID XM_001108540
Length 2098
MATDDKTSPTLDSANDLPRSPTSPSHLTHFKPLTPDQDEPPFKSAYSSFVNLFRFNKERAEGGQGEQQPLSGSWTSPQLPSRTQSVRSPTPYKKQLNEELQRRSSALDTRRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQYWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYCRKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRTPVGSRKASRNIFLEDDLAWQSLIHPDSSNTPLSTRLVSVQEDAGKSPARNRSASITNLSLDRSGSPMVPSYETSVSPQANRTYVRTETTEDERKILLDSVQLKDLWKKICHHSSGMEFQDHRYWLRTHPNCIVGKELVNWLIRNGHIATRAQAIAIGQAMVDGRWLDCVSHHDQLFRDEYALYRPLQSTEFSETPSPDSDSVNSVEGHSEPSWFKDIKFDDSDTEQIAEEGDDNLANSASPSKRTSVSSFQSTVDSDSAASISLNVELDNVNFHIKKPSKYPHVPPHPADQKEYLISDTGGQQLSISDAFIKESLFNRRVEEKSKELPFTPLGWHHNNLELLREENGEKQAMERLLSANHNHMMALLQQLLHSDSLSSSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNIAHKKMNSCIKNPKILLLKCSIEYLYREETKFTCIDPIVLQEREFLKNYVQRIVDVRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHLGTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEILIFMICVAYHSQLEISFLMDEFAMPPTLMQNPSFHSLIEGRGHEGTVQEQYGGGSLPWDPDIPPESLPCDDSSLLESRIVFEKGEQENKNVPQAVASVKHQEHSTTTCPAGLACAFFPPVPESLLPLPVDDQQDALGSEQPESLQQTVVLQDPKSQIRAFRDPLQDDTGLYVTEEVASSEDKRKTYSLAFKQELKDVILCISPVITFREPFLLTEKGMRCSTRDYFAEQVYWSPLLNKEFKEMENRRKKQLLRDLSGLQGMNGSIQAKCIQVLPSHELVSTRIAEHLGDSQSLGRMLADYRARGGRIQPKNSDPFAHSKDASSTSSGKSGSKNEGDEERGLIPNDAVWSTKVDCLNPINHQRLCVLFSSSSAQSSNAPSACVSPWIVTMEFYGKNDLTLGIFLERYCFRPSYQCPSMFCDTPMVHHIRRFVHGQGCVQIILKELDSPVPGYQHTILTYSWCRICKQVTPVVALSNESWSMSFAKYLELRFYGHQYTRRANAEPCGHSIHHDYHQYFSYNQMVASFSYSPIRLLEVCVPLPKIFIKRQAPLKVSLLQDLKDFFQKVSQVYIAIDERLASLKTDTFSKTREEKMEDIFAQKEMEEGEFKNWIEKMQARLMSSSVDTPQQLQSVFESLIAKKQSLCEVLQAWNNRLQDLFQQEKGRKRPSVPPSPGRLRQGEESKVSAMDASPRNISPGLQNGEKEDRFLTTLSSQSSTSSTHLQLPTPPEVMSEQSVGGPPELDTASSSEDVFDGHLLGSTDSQVKEKSTMKAIFANLLPGNSYNPIPFPFDPDKHYLMYEHERVPIAVCEKEPSSIIAFALSCKEYRNALEELSKVTQWNGAEEGLPTNSTLDSRPKSSSPIRLPEMSGGQTNRTAETEPQPTKKASGMLSFFRGTAGKSPDLSSQKRETLRGADSAYYQVGQTGKEGTENQGVEPQDEVDGGDTQKKQLINPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIIDYIRTFTWDKKLEMVVKSTGILGGQGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWTGLGLNC

Gene Information

Entrez Gene ID
710115
Gene Name
phosphoinositide kinase, FYVE finger containing
Gene Symbol
PIKFYVE
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005911 IEA:Ensembl C cell-cell junction
GO:0031410 IEA:Ensembl C cytoplasmic vesicle
GO:0005829 IEA:Ensembl C cytosol
GO:0031901 IEA:Ensembl C early endosome membrane
GO:0045121 IEA:Ensembl C membrane raft
GO:0048471 IEA:Ensembl C perinuclear region of cytoplasm
GO:0012506 IEA:Ensembl C vesicle membrane
GO:0016308 IEA:Ensembl F 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524 IEA:InterPro F ATP binding
GO:0008270 IEA:Ensembl F zinc ion binding
GO:0044267 IEA:InterPro P cellular protein metabolic process
GO:0035556 IEA:Ensembl P intracellular signal transduction
GO:0032288 IEA:Ensembl P myelin assembly
GO:0034504 IEA:Ensembl P protein localization to nucleus
GO:0042147 IEA:Ensembl P retrograde transport, endosome to Golgi

KEGG Pathway Links

KEGG Pathway ID Description
ko00562 Inositol phosphate metabolism
mcc00562 Inositol phosphate metabolism
ko04145 Phagosome
mcc04145 Phagosome
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
ko04810 Regulation of actin cytoskeleton
mcc04810 Regulation of actin cytoskeleton

Domain Information

InterPro Annotations

Accession Description
IPR002423 Chaperonin Cpn60/TCP-1
IPR000591 DEP domain
IPR000306 FYVE zinc finger
IPR027409 GroEL-like apical domain
IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
IPR027483 Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminal domain
IPR027410 TCP-1-like chaperonin intermediate domain
IPR011991 Winged helix-turn-helix DNA-binding domain
IPR011011 Zinc finger, FYVE/PHD-type
IPR017455 Zinc finger, FYVE-related
IPR013083 Zinc finger, RING/FYVE/PHD-type

UniProt Annotations

Entry Information

Gene Name
phosphoinositide kinase, FYVE finger containing
Protein Entry
F6UUQ5_MACMU
UniProt ID
F6UUQ5
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Contains PIPK domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014573 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109100777 RefSeq XP_001108540 2098 phosphoinositide kinase, FYVE finger containing

Identical Sequences to LMP014573 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP014573 proteins

Reference Database Accession Length Protein Name
GI:109100777 GenBank EHH55121.1 2098 hypothetical protein EGM_04264 [Macaca fascicularis]
GI:109100777 GenBank AFE65249.1 2098 1-phosphatidylinositol-3-phosphate 5-kinase isoform 2 [Macaca mulatta]
GI:109100777 RefSeq XP_005574164.1 2098 PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase isoform X5 [Macaca fascicularis]
GI:109100777 RefSeq XP_005574165.1 2098 PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase isoform X6 [Macaca fascicularis]