Gene/Proteome Database (LMPD)

LMPD ID
LMP014609
Gene ID
696860
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phospholipase C, delta 1
Gene Symbol
PLCD1
Alternate Names
phospholipase C, delta 1;
Chromosome
2
Map Location
chromosome:2
EC Number
3.1.4.11

Proteins

Refseq ID XP_001089399
Protein GI 109041761
UniProt ID F6VRS9
mRNA ID XM_001089399
Length 777
MQCLGIRSRSRSRELYLQEQSLKVAALNGRRLGLQDDEDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQEVRMGHRTEGLEKFARDVPEDRCFSIVFKDQRNTLDLIAPSPADAQHWVLGLRKIIHHSGSMDQRQKLRHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECDRSQTDSLEDEEIEAFYKMLTQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLSHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLQAILGPMLLNRQLDGVTNSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGFVRHNVGHLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACGYVLKPAFLRDPNATFNPRALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGVSRDVASRQTAVITNNGFNPWWDMEFAFEVVVPDLALVRFLVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLLSKNGDQHPSATLFVKISLQD

Gene Information

Entrez Gene ID
696860
Gene Name
phospholipase C, delta 1
Gene Symbol
PLCD1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:Ensembl C cytosol
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0005509 IEA:InterPro F calcium ion binding
GO:0070300 IEA:Ensembl F phosphatidic acid binding
GO:1901981 IEA:Ensembl F phosphatidylinositol phosphate binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0001786 IEA:Ensembl F phosphatidylserine binding
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0001525 IEA:Ensembl P angiogenesis
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0060716 IEA:Ensembl P labyrinthine layer blood vessel development
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0042127 IEA:Ensembl P regulation of cell proliferation

KEGG Pathway Links

KEGG Pathway ID Description
ko04020 Calcium signaling pathway
mcc04020 Calcium signaling pathway
ko00562 Inositol phosphate metabolism
mcc00562 Inositol phosphate metabolism
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc01100 Metabolic pathways
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
mcc04919 Thyroid hormone signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR028391 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
IPR000008 C2 domain
IPR018247 EF-Hand 1, calcium-binding site
IPR002048 EF-hand domain
IPR011992 EF-hand domain pair
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C, delta 1
Protein Entry
F6VRS9_MACMU
UniProt ID
F6VRS9
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains 2 EF-hand domains.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014609 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109041761 RefSeq XP_001089399 777 phospholipase C, delta 1

Identical Sequences to LMP014609 proteins

Reference Database Accession Length Protein Name
GI:109041761 GenBank EHH16510.1 777 hypothetical protein EGK_11798 [Macaca mulatta]

Related Sequences to LMP014609 proteins

Reference Database Accession Length Protein Name
GI:109041761 GenBank EHH51428.1 777 hypothetical protein EGM_10794 [Macaca fascicularis]
GI:109041761 RefSeq XP_003894726.1 777 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [Papio anubis]
GI:109041761 RefSeq XP_005546709.1 777 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [Macaca fascicularis]