Gene/Proteome Database (LMPD)

LMPD ID
LMP014610
Gene ID
715924
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phospholipase C, delta 3
Gene Symbol
PLCD3
Alternate Names
phospholipase C, delta 3;
Chromosome
16
Map Location
chromosome:16
EC Number
3.1.4.11

Proteins

Refseq ID XP_001115230
Protein GI 109116299
UniProt ID F7GU82
mRNA ID XM_001115230
Length 785
MLCGRWRRCRRPPEEPPVAAQVAAPVALPSPPTPSDGGTKRPGLRALKKMGLTEDEDVRAMLLGSRLRKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAPSQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEGAEIEEFLRRLLKRPELEEIFHQYSGEDRVLSAPELLEFLEDQGEEGATLARAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDTTHTCVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYIRAFAQGCRCVELDCWEGPGGEPIIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLRTILGDMLVTQALDSPNPEELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEDDDEEEEEEAETAAQRRLAKQISPELSALVVYCHATRLRTLHPAPDAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPEDPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRVEIHGVPADCARQETDYVLNNGFNPHWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATLFIQIRIQHP
Refseq ID XP_002800595
Protein GI 297273293
UniProt ID F7GU82
mRNA ID XM_001115230
Length 785
MLCGRWRRCRRPPEEPPVAAQVAAPVALPSPPTPSDGGTKRPGLRALKKMGLTEDEDVRAMLLGSRLRKIRSRTWHKERLYRLQEDGLSVWFQRRIPRAPSQHIFFVQHIEAVREGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEGAEIEEFLRRLLKRPELEEIFHQYSGEDRVLSAPELLEFLEDQGEEGATLARAQQLIQTYELNETAKQHELMTLDGFMMYLLSPEGAALDTTHTCVFQDMNQPLAHYFISSSHNTYLTDSQIGGPSSTEAYIRAFAQGCRCVELDCWEGPGGEPIIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLRTILGDMLVTQALDSPNPEELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEDDDEEEEEEAETAAQRRLAKQISPELSALVVYCHATRLRTLHPAPDAPQPCQVSSLSERKAKKLIREAGNSFVRHNARQLTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPACLRQPDSTFDPEDPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRVEIHGVPADCARQETDYVLNNGFNPHWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLSSLKQGYRHIHLLSKDGASLSPATLFIQIRIQPS

Gene Information

Entrez Gene ID
715924
Gene Name
phospholipase C, delta 3
Gene Symbol
PLCD3
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0001525 IEA:InterPro P angiogenesis
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process
GO:0042127 IEA:InterPro P regulation of cell proliferation

KEGG Pathway Links

KEGG Pathway ID Description
ko04020 Calcium signaling pathway
mcc04020 Calcium signaling pathway
ko00562 Inositol phosphate metabolism
mcc00562 Inositol phosphate metabolism
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc01100 Metabolic pathways
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
mcc04919 Thyroid hormone signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR028406 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
IPR000008 C2 domain
IPR018247 EF-Hand 1, calcium-binding site
IPR011992 EF-hand domain pair
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
IPR001849 Pleckstrin homology domain
IPR011993 Pleckstrin homology-like domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C, delta 3
Protein Entry
F7GU82_MACMU
UniProt ID
F7GU82
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Contains 1 C2 domain.
Similarity Contains 1 PH domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PH domain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014610 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109116299 RefSeq XP_001115230 785 phospholipase C, delta 3
297273293 RefSeq XP_002800595 785 phospholipase C, delta 3

Identical Sequences to LMP014610 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP014610 proteins

Reference Database Accession Length Protein Name
GI:297273293 RefSeq XP_003913243.1 785 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1 [Papio anubis]
GI:297273293 RefSeq XP_005584549.1 785 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [Macaca fascicularis]
GI:297273293 RefSeq XP_008010554.1 796 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X3 [Chlorocebus sabaeus]