Gene/Proteome Database (LMPD)

LMPD ID
LMP014619
Gene ID
703293
Species
Macaca mulatta (Rhesus monkey)
Gene Name
phospholipase C, zeta 1
Gene Symbol
PLCZ1
Alternate Names
phospholipase C, zeta 1;
Chromosome
11
Map Location
chromosome:11
EC Number
3.1.4.11

Proteins

Refseq ID XP_001095846
Protein GI 297261923
UniProt ID F6XHY0
mRNA ID XM_001095846
Length 608
MEMKWFLSKIQDDFRGGKINLEKTQRLLEKLDIRCSYIHVKRIFKDNDRLKQGRITIEEFRAIYRILTHREEIVEIFNAYSENRKILLENNLVQFLTQEQYTTEMSKTIAFEIIQKYEPIEEVRKARQMSLEGFTRYMDSRECQLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLVGPSDLWGYVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENHCSPAQQEIMADNLQTTFGESLLSDMLADFPDTLPSPEALKFKVLVKNKKIGTLKETHERKGSDKRGENQDKETGVKKLSGVTLFKKKKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQQFNENNSIGETQARKLSKLRAHEFIFHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGGSGYILKPHFLRESESYFNPSDIKDSMPITLTIRLISGIQLPLTHSSSNKGDTLVIIEVFGVPNDQMKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVESQGLIAGNEFLGQYTLPLLCMNKGYRRVPLFSRMGESLEPASLFVYVWYVR
Refseq ID XP_001096056
Protein GI 109095870
UniProt ID F6XHY0
mRNA ID XM_001095846
Length 641
MEMKWFLSKIQDDFRGGKINLEKTQRLLEKLDIRCSYIHVKRIFKDNDRLKQGRITIEEFRAIYRILTHREEIVEIFNAYSENRKILLENNLVQFLTQEQYTTEMSKTIAFEIIQKYEPIEEVRKARQMSLEGFTRYMDSRECQLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLVGPSDLWGYVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENHCSPAQQEIMADNLQTTFGESLLSDMLADFPDTLPSPEALKFKVLVKNKKIGTLKETHERKGSDKRGKVEEWEEEVADLEEEEEEEEKFKESEIFESVLGENQDKETGVKKLSGVTLFKKKKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQQFNENNSIGETQARKLSKLRAHEFIFHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGGSGYILKPHFLRESESYFNPSDIKDSMPITLTIRLISGIQLPLTHSSSNKGDTLVIIEVFGVPNDQMKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVESQGLIAGNEFLGQYTLPLLCMNKGYRRVPLFSRMGESLEPASLFVYVWYVR

Gene Information

Entrez Gene ID
703293
Gene Name
phospholipase C, zeta 1
Gene Symbol
PLCZ1
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005829 IEA:InterPro C cytosol
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004435 IEA:UniProtKB-EC F phosphatidylinositol phospholipase C activity
GO:0004871 IEA:UniProtKB-KW F signal transducer activity
GO:0006816 IEA:Ensembl P calcium ion transport
GO:0007343 IEA:Ensembl P egg activation
GO:0035556 IEA:InterPro P intracellular signal transduction
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko04020 Calcium signaling pathway
mcc04020 Calcium signaling pathway
ko00562 Inositol phosphate metabolism
mcc00562 Inositol phosphate metabolism
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc_M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
mcc01100 Metabolic pathways
ko04114 Oocyte meiosis
mcc04114 Oocyte meiosis
ko04070 Phosphatidylinositol signaling system
mcc04070 Phosphatidylinositol signaling system
mcc04919 Thyroid hormone signaling pathway

Domain Information

InterPro Annotations

Accession Description
IPR028395 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
IPR000008 C2 domain
IPR002048 EF-hand domain
IPR011992 EF-hand domain pair
IPR001192 Phosphoinositide phospholipase C family
IPR000909 Phospholipase C, phosphatidylinositol-specific , X domain
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
IPR015359 Phospholipase C, phosphoinositol-specific, EF-hand-like
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain

UniProt Annotations

Entry Information

Gene Name
phospholipase C, zeta 1
Protein Entry
F6XHY0_MACMU
UniProt ID
F6XHY0
Species
Rhesus monkey

Comments

Comment Type Description
Catalytic Activity 1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Contains 1 C2 domain.
Similarity Contains 1 EF-hand domain.
Similarity Contains 1 PI-PLC X-box domain.
Similarity Contains 1 PI-PLC Y-box domain.
Similarity Contains C2 domain.
Similarity Contains Cdomain.
Similarity Contains PI-PLC X-box domain.
Similarity Contains PI-PLC Y-box domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014619 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109095870 RefSeq XP_001096056 641 phospholipase C, zeta 1
297261923 RefSeq XP_001095846 608 phospholipase C, zeta 1

Identical Sequences to LMP014619 proteins

Reference Database Accession Length Protein Name
GI:109095870 DBBJ BAB63053.1 641 PLC-zeta [Macaca fascicularis]
GI:109095870 SwissProt Q95JS1.1 641 RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; AltName: Full=Phosphoinositide phospholipase C-zeta-1; AltName: Full=Phospholipase C-zeta-1; Short=PLC-zeta-1 [Macaca fascicularis]

Related Sequences to LMP014619 proteins

Reference Database Accession Length Protein Name
GI:109095870 DBBJ BAB63054.1 640 PLC-zeta [Macaca fascicularis]
GI:109095870 GenBank EHH66131.1 604 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1, partial [Macaca fascicularis]
GI:109095870 RefSeq XP_003906128.1 608 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X4 [Papio anubis]
GI:109095870 RefSeq XP_005570330.1 608 PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X3 [Macaca fascicularis]