Gene/Proteome Database (LMPD)

LMPD ID
LMP014727
Gene ID
695220
Species
Macaca mulatta (Rhesus monkey)
Gene Name
prostaglandin E receptor 4 (subtype EP4)
Gene Symbol
PTGER4
Alternate Names
prostaglandin E2 receptor EP4 subtype;
Chromosome
6
Map Location
chromosome:6

Proteins

prostaglandin E2 receptor EP4 subtype
Refseq ID NP_001252975
Protein GI 388453153
UniProt ID F7FTJ8
mRNA ID NM_001266046
Length 490
Protein sequence is identical to GI:109077062 (mRNA isoform)
Refseq ID XP_001085257
Protein GI 109077062
UniProt ID F7FTJ8
mRNA ID XM_001085375
Length 490
MSTPGVNASTSLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAATAVTSVVSRGHPAASPGLPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSRRTSSAMSGHSRSFFSRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQKDTTSLRTLRISETSDSSQGQDSESVLLVDEVGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
Refseq ID XP_001085375
Protein GI 109077064
UniProt ID F7FTJ8
mRNA ID XM_001085375
Length 490
Protein sequence is identical to GI:109077062 (mRNA isoform)

Gene Information

Entrez Gene ID
695220
Gene Name
prostaglandin E receptor 4 (subtype EP4)
Gene Symbol
PTGER4
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004957 ISS:UniProtKB F prostaglandin E receptor activity
GO:0007188 ISS:UniProtKB P adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0071260 IEA:Ensembl P cellular response to mechanical stimulus
GO:0050710 IEA:Ensembl P negative regulation of cytokine secretion
GO:2000420 ISS:UniProtKB P negative regulation of eosinophil extravasation
GO:0050728 ISS:UniProtKB P negative regulation of inflammatory response
GO:0033624 ISS:UniProtKB P negative regulation of integrin activation
GO:0050715 IEA:Ensembl P positive regulation of cytokine secretion
GO:0050729 IEA:Ensembl P positive regulation of inflammatory response
GO:0030278 IEA:Ensembl P regulation of ossification
GO:0051492 IEA:Ensembl P regulation of stress fiber assembly
GO:0032496 IEA:Ensembl P response to lipopolysaccharide
GO:0042093 IEA:Ensembl P T-helper cell differentiation

KEGG Pathway Links

KEGG Pathway ID Description
ko04750 Inflammatory mediator regulation of TRP channels
mcc04750 Inflammatory mediator regulation of TRP channels
ko04080 Neuroactive ligand-receptor interaction
mcc04080 Neuroactive ligand-receptor interaction

Domain Information

InterPro Annotations

Accession Description
IPR017452 GPCR, rhodopsin-like, 7TM
IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001244 Prostaglandin DP receptor
IPR001758 Prostanoid EP4 receptor
IPR008365 Prostanoid receptor

UniProt Annotations

Entry Information

Gene Name
prostaglandin E receptor 4 (subtype EP4)
Protein Entry
F7FTJ8_MACMU
UniProt ID
F7FTJ8
Species
Rhesus monkey

Identical and Related Proteins

Unique RefSeq proteins for LMP014727 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109077062 RefSeq XP_001085257 490 prostaglandin E receptor 4 (subtype EP4)

Identical Sequences to LMP014727 proteins

Reference Database Accession Length Protein Name
GI:388453153 GenBank AAL15041.1 490 prostaglandin E2 subtype EP4 receptor [Macaca fascicularis]
GI:388453153 GenBank AFH33329.1 490 prostaglandin E2 receptor EP4 subtype [Macaca mulatta]
GI:388453153 RefSeq XP_003899657.1 490 PREDICTED: prostaglandin E2 receptor EP4 subtype isoform X2 [Papio anubis]
GI:388453153 RefSeq XP_005556840.1 490 PREDICTED: prostaglandin E2 receptor EP4 subtype isoform X1 [Macaca fascicularis]

Related Sequences to LMP014727 proteins

Reference Database Accession Length Protein Name
GI:388453153 GenBank AAL15040.1 490 prostaglandin E2 subtype EP4 receptor [Papio ursinus]