Gene/Proteome Database (LMPD)

LMPD ID
LMP014989
Gene ID
707163
Species
Macaca mulatta (Rhesus monkey)
Gene Name
ubiquitin protein ligase E3 component n-recognin 5
Gene Symbol
UBR5
Alternate Names
ubiquitin protein ligase E3 component n-recognin 5;
Chromosome
8
Map Location
chromosome:8

Proteins

Refseq ID XP_001100326
Protein GI 109087122
UniProt ID F7HEG3
mRNA ID XM_001100326
Length 2799
MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAFLLEDGRVCRIGFSVQPDRLELGKPDNNDGSKLNSNSGAGRTSRPGRTSDSPWFLSGSETLGRLAGNTLGSRWSSGVGGSGGGSSGRSSAGARDSRRQTRVIRTGRDRGSGLLGSQPQPVIPASVIPEELISQAQVVLQGKSRSVIIRELQRTNLDVNLAVNNLLSRDDEDGDDGDDTASESYLPGEDLMSLLDADIHSAHPSVIIDADAMFSEDISYFGYPSFRRSSLSRLGSSRVLLLPLERDSELLRERESVLRLRERRWLDGASFDNERGSTSKEGEPNLDKKNTPVQSPVSLGEDLQWWPDKDGTKFICIGALYSELLAVSSKGELYQWKWSESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRNNPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPESKQEPVKTEMGPPPSPASTCSDASSIASSASMPYKRRRSTPAPKEEEKVNEEQWSLREVVFVEDVKNVPVGKVLKVDGAYVAVKFPGTSSNTNCQSSSGPDADPSSLLQDCRLLRIDELQVVKTGGTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQENNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPISSLGMGVHSLINLPANSTIKKKAAIIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVVLEQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKETKEEEEAERSERNTFAERLSAVEAIANAISVVSSNGPGNRAGSSSSRSLRLREMMRRSLRAAGLGRHEAGASSSDHQDPVSPPIAPPSWVPDPPAMDPDGDIDFILAPAVGSLTTAATGTGQGPSTSTIPGPSTEPSVVESKDRKANAHFILKLLCDSVVLQPYLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEVSSSEKEEDVFMGMVCPSGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHDCKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLVQTVARQTVEHCQYRPPRIREDRNRKTASPEDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQENKDPLSASSRIGHLLPEEQVYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQNKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCKRVFQALLPYAVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSDQSSSSSQSQSSYIIRNPQQRRISQSQPVRGRDEEQDDIVSADVEEVEVVEGVAGEEDHHDEQEEHGEENAEAEGQHDEHDEDGSDMELDLLAAAETESDSESNHSNQDNASGRRSVVTAATAGSEAGASSVPAFFSEDDSQSNDSSDSDSSSSQSDDIEQETFMLDEPLERTTNSSHANGAAQAPRSMQWAVRNTQHQRAASTAPSSTSTPAASSAGLIYIDPSNLRRSGTISTSAAAAAAALEASNASSYLTSASSLARAYSIVIRQISDLMGLIPKYNHLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPGHPNHPLHASQNSARRERMTAREEASLRTLEGRRRATLLSARQGMMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALIYWIKAMNQQTTLDTPQLERKRTRELLELGIDNEDSEHENDDDTNQSATLNDKDDDSLPAETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARKEDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPTKMSYAANLKNVMNMQNRQKKEGEEQPVLPEEAESSKPGPSAHDLAAQLKSSLLAEIGLTESEGPPLTSFRPQCSFMGMVISHDMLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSLEVDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAFLSNEKLPNLECIQNANKGTHTSLMQRLRNRGERDREREREREMRRSSGLRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPDPLPAHRQALGERLYPRVQAMQPAFASKITGMLLELSPAQLLLLLASEDSLRARVDEAMELIIAHGRENGADSILDLGLVDSSEKVQQENRKRHGSSRSVVDMDLDDTDDGDDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNELCPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAIDLCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKNSLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTERQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKTKNFGFV

Gene Information

Entrez Gene ID
707163
Gene Name
ubiquitin protein ligase E3 component n-recognin 5
Gene Symbol
UBR5
Species
Macaca mulatta

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016020 IEA:Ensembl C membrane
GO:0005634 IEA:Ensembl C nucleus
GO:0003723 IEA:InterPro F RNA binding
GO:0016874 IEA:UniProtKB-KW F ligase activity
GO:0034450 IEA:Ensembl F ubiquitin-ubiquitin ligase activity
GO:0008270 IEA:InterPro F zinc ion binding
GO:0006974 IEA:Ensembl P cellular response to DNA damage stimulus
GO:2000780 IEA:Ensembl P negative regulation of double-strand break repair
GO:1901315 IEA:Ensembl P negative regulation of histone H2A K63-linked ubiquitination
GO:0090263 IEA:Ensembl P positive regulation of canonical Wnt signaling pathway
GO:0035413 IEA:Ensembl P positive regulation of catenin import into nucleus
GO:0033160 IEA:Ensembl P positive regulation of protein import into nucleus, translocation
GO:0050847 IEA:Ensembl P progesterone receptor signaling pathway
GO:0000209 IEA:Ensembl P protein polyubiquitination

KEGG Pathway Links

KEGG Pathway ID Description
ko04120 Ubiquitin mediated proteolysis
mcc04120 Ubiquitin mediated proteolysis

Domain Information

InterPro Annotations

Accession Description
IPR024725 E3 ubiquitin ligase EDD, ubiquitin-associated domain
IPR000569 HECT
IPR002004 Polyadenylate-binding protein/Hyperplastic disc protein
IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
IPR003126 Zinc finger, N-recognin
IPR013993 Zinc finger, N-recognin, metazoa

UniProt Annotations

Entry Information

Gene Name
ubiquitin protein ligase E3 component n-recognin 5
Protein Entry
F7HEG3_MACMU
UniProt ID
F7HEG3
Species
Rhesus monkey

Comments

Comment Type Description
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Similarity Contains HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Similarity Contains PABC domain.

Identical and Related Proteins

Unique RefSeq proteins for LMP014989 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
109087122 RefSeq XP_001100326 2799 ubiquitin protein ligase E3 component n-recognin 5

Identical Sequences to LMP014989 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP014989 proteins

Reference Database Accession Length Protein Name
GI:109087122 GenBank AFH28983.1 2799 E3 ubiquitin-protein ligase UBR5 [Macaca mulatta]
GI:109087122 RefSeq XP_003940725.1 2799 PREDICTED: E3 ubiquitin-protein ligase UBR5 isoform X3 [Saimiri boliviensis boliviensis]
GI:109087122 RefSeq XP_005563892.1 2799 PREDICTED: E3 ubiquitin-protein ligase UBR5 isoform X1 [Macaca fascicularis]
GI:109087122 RefSeq XP_007999449.1 2799 PREDICTED: E3 ubiquitin-protein ligase UBR5 isoform X3 [Chlorocebus sabaeus]