Structure Database (LMSD)

Common Name
N-(3-oxo-butanoyl)-homoserine lactone
Systematic Name
N-(3-oxo-butanoyl)-homoserine lactone
Synonyms
  • 3-oxo-C4:0-HSL
LM ID
LMFA08030028
Formula
Exact Mass
Calculate m/z
185.068809
Status
Curated

Classification

Biological Context

N-3-oxo-butyryl-L-Homoserine lactone is a bacterial quorum-sensing signaling molecule.1 It induces expression of rhiI in R. leguminosarum, a gene with roles in the interaction of the rhizosphere with legumes.

This information has been provided by Cayman Chemical

References

1. Rodelas, B., Lithgow, J.K., Wisniewski-Dye, F., et al. Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae. J. Bacteriol. 181(12), 3816-3823 (1999).

References

Reference
Detection of acyl-homoserine lactones by Escherichia and Salmonella. Jitesh A. Soares and Brian M. M. Ahmer. Current Opinion in Microbiology. Volume 14, Issue 2, April 2011, Pages 188-193. https://doi.org/10.1016/j.mib.2011.01.006

https://www.sciencedirect.com/science/article/pii/S136952741100018X#bib0080

String Representations

InChiKey (Click to copy)
FIHPLICEAUNEFV-LURJTMIESA-N
InChi (Click to copy)
InChI=1S/C8H11NO4/c1-5(10)4-7(11)9-6-2-3-13-8(6)12/h6H,2-4H2,1H3,(H,9,11)/t6-/m0/s1
SMILES (Click to copy)
[C@@H]1(CCOC1=O)NC(=O)CC(=O)C

Other Databases

CHEBI ID
PubChem CID
Cayman ID

Calculated Physicochemical Properties

Heavy Atoms 13
Rings 1
Aromatic Rings 0
Rotatable Bonds 3
Van der Waals Molecular Volume 172.84
Topological Polar Surface Area 74.54
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
logP -0.03
Molar Refractivity 43.81

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Created at
1st Jul 2019
Updated at
1st Jul 2019