Structure Database (LMSD)
Common Name
PE(0:0/20:4;O)
Systematic Name
2-(12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine
Synonyms
- 12S-HETE-LPE
LM ID
LMGP20020058
Formula
Exact Mass
Calculate m/z
517.280457
Sum Composition
Abbrev Chains
LPE 0:0/20:4;O
Status
Active
3D model of PE(0:0/20:4;O)
Please note: Where there are chiral atoms but the stereochemistry is undefined, the 3D model takes an arbitrary conformation
Main
Classification
Category
Main Class
Sub Class
String Representations
InChiKey (Click to copy)
JKTUUJJZYBGXLH-CNZMPJCYSA-N
InChi (Click to copy)
InChI=1S/C25H44NO8P/c1-2-3-4-5-10-13-16-23(28)17-14-11-8-6-7-9-12-15-18-25(29)34-24(21-27)22-33-35(30,31)32-20-19-26/h7-11,13-14,17,23-24,27-28H,2-6,12,15-16,18-22,26H2,1H3,(H,30,31)/b9-7-,11-8-,13-10-,17-14+/t23-,24+/m0/s1
SMILES (Click to copy)
C(O[C@@]([H])(COP(O)(=O)OCCN)CO)(CCC/C=C\C/C=C\C=C\[C@@H](O)C/C=C\CCCCC)=O
References
Taxonomy Information
Curated from
NCBI taxonomy class
Reference
Mus musculus
(#10090)
Mammalia
(#40674)
12-LOX catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA2γ knockout.,
J Biol Chem, 2020
J Biol Chem, 2020
Pubmed ID:
32161117
Other Databases
PubChem CID
Calculated Physicochemical Properties
Heavy Atoms
35
Rings
0
Aromatic Rings
0
Rotatable Bonds
23
Van der Waals Molecular Volume
529.01
Topological Polar Surface Area
148.54
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
9
logP
5.98
Molar Refractivity
140.39
Admin
Created at
27th Aug 2020
Updated at
25th Apr 2022
LIPID MAPS® abbreviations for glycerophospholipids (GP)
The LIPID MAPS® glycerophospholipid abbreviations (PC, PE, etc.) are used here to refer to species with one or two radyl side-chains where the structures of the side chains are indicated within parentheses in the 'Headgroup(sn1/sn2)' format (e.g. PC(16:0/18:1(9Z)). By default, R stereochemistry at the C-2 carbon of glycerol and attachment of the headgroup at the sn3 position is assumed. Also, acyl chains are assumed by default. The 'O-' prefix is used to indicate the presence of an alkyl ether substituent e.g. PC(O-16:0/18:1(9Z)), whereas the 'P-' prefix is used for the 1Z-alkenyl ether (Plasmalogen) substituent e.g. PC(P-16:0/18:1(9Z)).
For molecules with opposite (S) stereochemistry at C2 of the glycerol group and attachment of the headgroup at the sn1 position, the stereochemistry specification of [S] is appended to the abbreviation. The 'Headgroup(sn3/sn2)' abbreviation format is used.
For molecules with unknown stereochemistry at the C-2 carbon of the glycerol group, the stereochemistry specification of [U] is appended to the abbreviation and the structure is drawn with C-2 stereochemistry unspecified.
The LIPID MAPS® glycerophospholipid abbreviations (PC, PE, etc.) are used here to refer to species with one or two radyl side-chains where the structures of the side chains are indicated within parentheses in the 'Headgroup(sn1/sn2)' format (e.g. PC(16:0/18:1(9Z)). By default, R stereochemistry at the C-2 carbon of glycerol and attachment of the headgroup at the sn3 position is assumed. Also, acyl chains are assumed by default. The 'O-' prefix is used to indicate the presence of an alkyl ether substituent e.g. PC(O-16:0/18:1(9Z)), whereas the 'P-' prefix is used for the 1Z-alkenyl ether (Plasmalogen) substituent e.g. PC(P-16:0/18:1(9Z)).
For molecules with opposite (S) stereochemistry at C2 of the glycerol group and attachment of the headgroup at the sn1 position, the stereochemistry specification of [S] is appended to the abbreviation. The 'Headgroup(sn3/sn2)' abbreviation format is used.
For molecules with unknown stereochemistry at the C-2 carbon of the glycerol group, the stereochemistry specification of [U] is appended to the abbreviation and the structure is drawn with C-2 stereochemistry unspecified.