Structure Database (LMSD)
Common Name
Glabridin
Systematic Name
Synonyms
3D model of Glabridin
Please note: Where there are chiral atoms but the stereochemistry is undefined, the 3D model takes an arbitrary conformation
Classification
Biological Context
Glabridin is a prenylated isoflavonoid found in licorice root extract that is reported to possess antiviral, antimicrobial, anti-inflammatory, antidiabetic, antiatherogenic, antioxidant, antitumor, and estrogen-like properties.1,2,3 These diverse biological activities are largely related to the capacity of glabridin to down-regulate reactive oxygen species, bind to antioxidant effectors, and act as a selective estrogen receptor modulator.4
This information has been provided by Cayman Chemical
References
1. Lee, K.J., Oh, Y.C., Cho, W.K., et al. Antioxidant and anti-inflammatory activity determination of one hundred kinds of pure chemical compounds using offline and online screening HPLC assay. Evid. Based Complement. Alternat. Med. 165457 (2015).
2. Ming, L.J., and Yin, A.C. Therapeutic effects of glycyrrhizic acid. Nat. Prod. Commun. 8(3), 415-418 (2013).
References
Taxonomy Information
Curated from
NCBI taxonomy class
Reference
Viridiplantae
(#33090)
Flavonoid imported from http://metabolomics.jp/
String Representations
InChiKey (Click to copy)
LBQIJVLKGVZRIW-ZDUSSCGKSA-N
InChi (Click to copy)
InChI=1S/C20H20O4/c1-20(2)8-7-16-18(24-20)6-3-12-9-13(11-23-19(12)16)15-5-4-14(21)10-17(15)22/h3-8,10,13,21-22H,9,11H2,1-2H3/t13-/m0/s1
SMILES (Click to copy)
C12OC(C)(C)C=CC1=C1OC[C@@]([H])(C3C(O)=CC(O)=CC=3)CC1=CC=2
Other Databases
Calculated Physicochemical Properties
Heavy Atoms
24
Rings
4
Aromatic Rings
2
Rotatable Bonds
1
Van der Waals Molecular Volume
300.00
Topological Polar Surface Area
63.06
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
logP
4.57
Molar Refractivity
92.90
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Updated at
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