Structure Database (LMSD)
Common Name
Myricetin
Systematic Name
3,3?,4?,5,5?,7-Hexahydroxyflavone
Synonyms
- Cannabiscetin
- Myricetol
- Myricitin
3D model of Myricetin
Please note: Where there are chiral atoms but the stereochemistry is undefined, the 3D model takes an arbitrary conformation
Classification
Biological Context
Myricetin is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant.1 Myricetin inhibits TBARS formation with an IC50 value of 6.34 and at 20 µM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression.2 Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.3,4
This information has been provided by Cayman Chemical
References
2. Kumamoto, T., Fujii, M., and Hou, D.X. Myricetin directly targets JAK1 to inhibit cell transformation. Cancer Lett. 275(1), 17-26 (2009).
References
String Representations
InChiKey (Click to copy)
IKMDFBPHZNJCSN-UHFFFAOYSA-N
InChi (Click to copy)
InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
SMILES (Click to copy)
C1(O)C=C2OC(C3=CC(O)=C(O)C(O)=C3)=C(O)C(=O)C2=C(O)C=1
Other Databases
Calculated Physicochemical Properties
Heavy Atoms
23
Rings
3
Aromatic Rings
3
Rotatable Bonds
1
Van der Waals Molecular Volume
247.48
Topological Polar Surface Area
151.59
Hydrogen Bond Donors
6
Hydrogen Bond Acceptors
8
logP
2.59
Molar Refractivity
78.02
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Created at
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Updated at
3rd Apr 2025