LIPID MAPS

Structure Database (LMSD)

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Common Name

Ginkgolide C

Systematic Name

Synonyms

LM ID

LMPR0104540003

Formula

C₂₀H₂₄O₁₁

Exact Mass

Calculate m/z

440.131865

Status

Curated

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Classification

Biological Context

Ginkgolide C is a flavone first extracted from G. biloba leaves with multiple reported biological functions. It has been identified as a selective platelet activating factor receptor antagonist (IC50 = 37.6 μM).¹ Ginkgolide C has also been shown to increase lipolysis and to inhibit adipogenesis in adipocytes via the activated AMPK pathway.²

This information has been provided by Cayman Chemical

References

1. Braquet, P., Esanu, A., Buisine, E., et al. Recent progress in ginkgolide research. Med. Res. Rev. 11(3), 295-355 (1991).

2. Liou, C.-J., Lai, X.-Y., Chen, Y.-L., et al. Ginkgolide C suppresses adipogenesis in 3T3-L1 adipocytes via the AMPK signaling pathway. Evid. Based Complement. Alternat. Med. 2015:298635, (2015).

References

Taxonomy Information

Curated from

NCBI taxonomy class

Reference

Ginkgo biloba (#3311)

Ginkgoopsida (#29811)

Structure and absolute configuration of ginkgolide B characterized by IR- and VCD spectroscopy.,
Chirality, 2010

Pubmed ID: 19455619

String Representations

InChiKey (Click to copy)

AMOGMTLMADGEOQ-AEXCBEIUSA-N

InChi (Click to copy)

InChI=1S/C20H24O11/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,21-23,27H,1-4H3/t5-,6-,7+,8+,9+,10-,11+,15+,17?,18?,19-,20-/m1/s1

SMILES (Click to copy)