Structure Database (LMSD)

Common Name
2alpha-chloro-1beta,25-dihydroxyvitamin D3
Systematic Name
(5Z,7E)-(1S,2S,3R)-2-chloro-9,10-seco-5,7,10(19)-cholestatriene-1,3,25-triol
Synonyms
  • 2alpha-chloro-1beta,25-dihydroxycholecalciferol
LM ID
LMST03020196
Formula
C27H43O3Cl
Exact Mass
Calculate m/z
450.290073
Status
Active
Show lipids differing only in stereochemistry/bond geometry

Classification

Category
Main Class
Sub Class
Sterol Lipids [ST]
Secosteroids [ST03]
Vitamin D3 and derivatives [ST0302]

References

Taxonomy Information

Curated from
NCBI taxonomy class
Reference
synthetic construct (#32630)
Synthesis and biological activities of 2 alpha-chloro-1-epicalcitriol and 1-epicalcitriol.,
Steroids, 1998
Pubmed ID: 9437792

String Representations

InChiKey (Click to copy)
YBTPGKMEEDFQBI-CHGYUPLRSA-N
InChi (Click to copy)
InChI=1S/C27H43ClO3/c1-17(8-6-14-26(3,4)31)21-12-13-22-19(9-7-15-27(21,22)5)10-11-20-16-23(29)24(28)25(30)18(20)2/h10-11,17,21-25,29-31H,2,6-9,12-16H2,1,3-5H3/b19-10+,20-11-/t17-,21-,22+,23-,24+,25+,27-/m1/s1
SMILES (Click to copy)
[C@H]1(O)C(=C)/C(=C\C=C2\[C@]3([H])CC[C@@]([C@@](C)([H])CCCC(O)(C)C)([H])[C@@]3(C)CCC\2)/C[C@@H](O)[C@@H]1Cl

Other Databases

CHEBI ID
178629
LIPIDBANK ID
VVD0214
PubChem CID
9547407

Calculated Physicochemical Properties

Heavy Atoms 31
Rings 3
Aromatic Rings 0
Rotatable Bonds 6
Van der Waals Molecular Volume 472.24
Topological Polar Surface Area 60.69
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 3
logP 7.07
Molar Refractivity 131.11

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Created at
-
Updated at
15th Feb 2022