Structure Database (LMSD)

H H H HO F OH
Common Name
(24R)-25-fluoro-24-hydroxyvitamin D3
Systematic Name
(5Z,7E)-(3S,24R)-25-fluoro-9,10-seco-5,7,10(19)-cholestatriene-3,24-diol
Synonyms
  • (24R)-25-fluoro-24-hydroxycholecalciferol
LM ID
LMST03020208
Formula
C27H43O2F
Exact Mass
Calculate m/z
418.324708
Status
Active
Show lipids differing only in stereochemistry/bond geometry

Main

Classification

Category
Main Class
Sub Class
Sterol Lipids [ST]
Secosteroids [ST03]
Vitamin D3 and derivatives [ST0302]

String Representations

InChiKey (Click to copy)
MKHHZRCEBZKSNE-XRWYNYHCSA-N
InChi (Click to copy)
InChI=1S/C27H43FO2/c1-18-8-12-22(29)17-21(18)11-10-20-7-6-16-27(5)23(13-14-24(20)27)19(2)9-15-25(30)26(3,4)28/h10-11,19,22-25,29-30H,1,6-9,12-17H2,2-5H3/b20-10+,21-11-/t19-,22+,23-,24+,25-,27-/m1/s1
SMILES (Click to copy)
C1C(=C)/C(=C\C=C2\[C@]3([H])CC[C@@]([C@@](C)([H])CC[C@@H](O)C(F)(C)C)([H])[C@@]3(C)CCC\2)/C[C@@H](O)C1

References

Taxonomy Information

Curated from
NCBI taxonomy class
Reference
synthetic construct (#32630)
Synthesis and biological activity of 24-hydroxy-25-fluorovitamin D3. A highly potent mediator of calcium metabolism.,
J Biol Chem, 1979
Pubmed ID: 217876

Other Databases

LIPIDBANK ID
VVD0226
PubChem CID
9547419

Calculated Physicochemical Properties

Heavy Atoms 30
Rings 3
Aromatic Rings 0
Rotatable Bonds 6
Van der Waals Molecular Volume 454.31
Topological Polar Surface Area 40.46
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 2
logP 7.54
Molar Refractivity 124.46

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Created at
-
Updated at
11th Dec 2023