Structure Database (LMSD)

H H H HO OH OH F
Common Name
(10Z)-19-fluoro-1alpha,25-dihydroxyvitamin D3
Systematic Name
(5Z,7E,10Z)-(1S,3R)-19-fluoro-9,10-seco-5,7,10(19)-cholestatriene-1,3,25-triol
Synonyms
  • (10Z)-19-fluoro-1alpha,25-dihydroxycholecalciferol
LM ID
LMST03020212
Formula
C27H43O3F
Exact Mass
Calculate m/z
434.319623
Status
Active
Show lipids differing only in stereochemistry/bond geometry

Main

Classification

Category
Main Class
Sub Class
Sterol Lipids [ST]
Secosteroids [ST03]
Vitamin D3 and derivatives [ST0302]

String Representations

InChiKey (Click to copy)
FYKDFTBGRZTDCR-FZTNSQDISA-N
InChi (Click to copy)
InChI=1S/C27H43FO3/c1-18(7-5-13-26(2,3)31)23-11-12-24-19(8-6-14-27(23,24)4)9-10-20-15-21(29)16-25(30)22(20)17-28/h9-10,17-18,21,23-25,29-31H,5-8,11-16H2,1-4H3/b19-9+,20-10-,22-17-/t18-,21-,23-,24+,25+,27-/m1/s1
SMILES (Click to copy)
[C@@H]1(O)/C(=C\F)/C(=C\C=C2\[C@]3([H])CC[C@@]([C@@](C)([H])CCCC(O)(C)C)([H])[C@@]3(C)CCC\2)/C[C@@H](O)C1

References

Taxonomy Information

Curated from
NCBI taxonomy class
Reference
synthetic construct (#32630)
(10Z)- and (10E)-19-fluoro-1alpha,25-dihydroxyvitamin D3: an improved synthesis via 19-nor-10-oxo-vitamin D.,
Chem Pharm Bull (Tokyo), 2001
Pubmed ID: 11253922

Other Databases

LIPIDBANK ID
VVD0230
PubChem CID
9547423

Calculated Physicochemical Properties

Heavy Atoms 31
Rings 3
Aromatic Rings 0
Rotatable Bonds 6
Van der Waals Molecular Volume 463.10
Topological Polar Surface Area 60.69
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 3
logP 6.86
Molar Refractivity 125.63

Admin

Created at
-
Updated at
13th Dec 2023