The group of Minnaard is active in organic chemistry, specifically in organic synthesis, focussing on the ability to chemically prepare complex molecules, based on in-house developed catalysis methodology. Parts of his work are carried out in close collaboration with other groups in chemistry (Codée, Bickelhaupt), biology (Gilleron, CNRS Toulouse, and Yamasaki, Osaka University), and medicine (Moody, Harvard Med School, Seshadri, U. Washington). By working together with leading groups in tuberculosis research, the group makes fundamental discoveries in the immunology of this disease and unravels how tuberculosis bacteria survive in macrophages. The research spans the entire chain from fundamental science to novel diagnostics and antibiotics to combat TB. The fundamental research is funded by NWO, and the NIH. The more applied research is funded by the Gates Foundation and industry. With the planned launch of a novel diagnostic test for TB worldwide by Minnaard’s initiated UG spin-off company, its mission is on its way to being accomplished.