Uncovering complexity of natural epilipidomes
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About Dr Maria Fedorova
Maria
Fedorova studied Biochemistry at Saint-Petersburg State University, Russia and
obtained her PhD at Faculty of Chemistry and Mineralogy, Leipzig University,
Germany. Now she is a group leader at the Institute of Bioanalytical Chemistry,
Faculty of Chemistry and Mineralogy, at the University of Leipzig. Her research
is focused on development and optimization of chromatography and mass
spectrometry methods for analysis of lipids and their modified forms. Dr
Fedorova group works on implementation of high throughput LC-MS methods in
discovery lipidomics targeting in-depth identification and quantification of
human lipidome in variety of tissues. By combining lipidomics data with
investigation of related proteins and protein post-translational modifications via
systems medicine approach, Dr Fedorova aims for a deeper understanding of
pathophysiology of obesity, insulin resistance, type II diabetes and
cardiovascular disorders. Another focus of Dr Fedorova’s research is the development and application of mass spectrometry-based
methods for analysis of protein and lipid modifications, including
lipid-protein adducts. She is working to understand the role of redox lipid and
protein signaling in the onset and progression of human disorders associated
with chronic inflammation, including cardiovascular and metabolic diseases.