Analysis of ether lipid structures, metabolic bias, and roles in ferroptosis
Presented by:
Takeshi Harayama
Synopsis
Attendees will learn about:
1. An untargeted lipidomics approach that annotates lipid peaks with less errors, more coverage, and more structural insights than what is possible with typical fragmentation methods
2. The dissection of metabolic pathways regulating the composition of lipids having ether linkages
3. How ether lipid structures affect ferroptotic cell death
1. An untargeted lipidomics approach that annotates lipid peaks with less errors, more coverage, and more structural insights than what is possible with typical fragmentation methods
2. The dissection of metabolic pathways regulating the composition of lipids having ether linkages
3. How ether lipid structures affect ferroptotic cell death
About Takeshi Harayama
Takeshi Harayama is a group leader at Institut de Pharmacologie Moléculaire et Cellulaire (Université Côte d’Azur, CNRS, Inserm) in France. He received his Ph.D. in 2011 at the University of Tokyo (Japan) under the supervision of Takao Shimizu. After doing postdoctoral studies in the same team, he joined the team of Howard Riezman at the University of Geneva (Switzerland) in 2015 as a postdoctoral researcher. He then moved to France in 2020 for his current position. His team studies the metabolic regulation and biological relevance of membrane lipid structures using genetics, cell biology, and lipidomics.
Takeshi Harayama