Pathways

LIPID MAPS® Pathways

LIPID MAPS® Pathways created in collaboration with WikiPathways. Pathways include metabolism of:

add Fatty Acyls

• Eicosanoid metabolism via Cyclooxygenases (COX) (Mus musculus)
• Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway
• Eicosanoid metabolism via Lipoxygenases (LOX) (Mus musculus)
• Eicosanoid Synthesis (Homo sapiens)
• Omega-3/Omega-6 FA synthesis (Mus musculus)
• Omega-9 FA synthesis (Mus musculus)
• Octadecanoid formation from linoleic acid (Homo sapiens)

add Glycerolipids

• Glycerolipids and Glycerophospholipids (Mus musculus)

add Glycerophospholipids

• Glycerolipids and Glycerophospholipids (Mus musculus)
• Ether lipid biosynthesis (Homo sapiens)

add Sphingolipids

• Sphingolipid Metabolism (general overview) (Mus musculus)
• Sphingolipid Metabolism (integrated pathway) (Mus musculus)
• Glycosphingolipid metabolism (Homo sapiens)
• Ganglio series sphingolipid metabolism (Homo sapiens)
• Lacto series sphingolipid metabolism (Homo sapiens)
• Bacterial ceramide synthesis (Caulobacter vibrioides)

add Sterols

• Cholesterol metabolism - includes both Bloch and Kandutsch-Russell pathways (Mus musculus)
• Oxysterols derived from cholesterol (Homo sapiens)
• Steroid hormone precursor biosynthesis (Homo sapiens)
• Estrogen metabolism (Homo sapiens)
• Mineralocorticoid biosynthesis (Homo sapiens)
• Glucocorticoid biosynthesis (Homo sapiens)

References

• Slenter DN, Kutmon M, Hanspers K, Riutta A, Windsor J, Nunes N, Mélius J, Cirillo E, Coort SL, Digles D, Ehrhart F, Giesbertz P, Kalafati M, Martens M, Miller R, Nishida K, Rieswijk L, Waagmeester A, Eijssen LMT, Evelo CT, Pico AR, Willighagen EL.
  WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research Nucleic Acids Research, (2017)
  DOI: 10.1093/nar/gkx1064  PMCID: PMC5753270