Microarray analysis of bone marrow-derived macrophage cells treated with Kdo2-lipid A (KLA) and ATP

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Kdo2-Lipid A / ATP gene array data - treatment:control ratios

KEGG pathway: Basal transcription factors (mmu03022)

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Gene symbol    Time course plot Accession Description Treatment 15min 30min 1hr 2hr 4hr 8hr 20hr
4933416C
03Rik
KLA  ATP  ATP+KLA
 AK133409 adult male testis cDNA, RIKEN full-length enriched library, clone:4933416C03 product:hypothetical protein, full insert sequence [AK133409] KLA 1.02 1.09 .96 1.02 1.03 .99 1.00
ATP .95 1.02 1.07 1.00 .96 .98 .99
KLA/ATP .95 1.00 1.03 1.02 .96 .98 .99
AK031249
KLA  ATP  ATP+KLA
 AK031249 13 days embryo forelimb cDNA, RIKEN full-length enriched library, clone:5930437C20 product:hypothetical protein, full insert sequence [AK031249] KLA .95 1.00 .98 .99 .96 1.01 1.07
ATP .92 1.02 1.10 1.15 1.22 1.03 1.01
KLA/ATP .96 .97 1.10 1.15 1.05 1.11 1.02
BB483579
KLA  ATP  ATP+KLA
 BB483579 gb|BB483579 RIKEN full-length enriched, 13 days embryo lung Mus musculus cDNA clone D430021C16 3. [BB483579] KLA .99 1.01 .84 .82 .90 .92 .99
ATP .95 .84 .71 .82 .86 .89 .96
KLA/ATP .91 .84 .78 .79 .84 .96 .94
Ccnh
KLA  ATP  ATP+KLA
 NM_023243 cyclin H (Ccnh), mRNA [NM_023243] KLA .68 .70 .59 .60 .51 .67 .86
ATP .95 .98 1.23 1.05 .60 .37 .85
KLA/ATP .65 .63 .70 .61 .44 .33 .44
Cdk7
KLA  ATP  ATP+KLA
 NM_009874 cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase) (Cdk7), mRNA [NM_009874] KLA 1.18 1.15 1.15 1.13 1.08 1.01 1.19
ATP 1.01 1.06 .92 .72 1.06 1.79 1.12
KLA/ATP 1.11 1.23 1.45 .81 .88 1.24 .93
Ercc2
KLA  ATP  ATP+KLA
 NM_007949 excision repair cross-complementing rodent repair deficiency, complementation group 2 (Ercc2), mRNA [NM_007949] KLA 1.04 1.08 1.07 1.00 1.03 1.04 1.17
ATP .95 1.04 .86 .82 .81 1.01 .98
KLA/ATP 1.03 1.08 1.00 .83 .71 .84 .85
Ercc3
KLA  ATP  ATP+KLA
 NM_133658 excision repair cross-complementing rodent repair deficiency, complementation group 3 (Ercc3), mRNA [NM_133658] KLA .96 1.06 1.09 1.04 1.10 1.22 1.08
ATP 1.08 1.15 1.02 1.04 .81 1.05 1.53
KLA/ATP 1.07 1.16 .98 1.06 .83 1.08 1.52
Gtf2a1
KLA  ATP  ATP+KLA
 NM_031391 general transcription factor II A, 1 (Gtf2a1), transcript variant 1, mRNA [NM_031391] KLA 1.74 2.02 2.33 2.45 2.38 2.26 1.91
ATP 1.06 1.13 1.15 2.00 2.43 2.08 2.85
KLA/ATP 1.95 2.13 1.96 2.45 2.36 2.55 3.77
Gtf2a1
KLA  ATP  ATP+KLA
 NM_175335 general transcription factor II A, 1 (Gtf2a1), transcript variant 2, mRNA [NM_175335] KLA 2.86 2.89 2.85 3.56 3.35 2.78 1.89
ATP 1.11 1.17 1.29 2.22 2.67 3.03 4.04
KLA/ATP 2.30 3.24 3.58 3.33 3.09 3.08 4.94
Gtf2a1l
KLA  ATP  ATP+KLA
 NM_023630 general transcription factor IIA, 1-like (Gtf2a1l), mRNA [NM_023630] KLA 1.02 .96 1.05 1.07 1.11 1.02 1.04
ATP .99 .97 1.08 1.01 .99 1.01 .99
KLA/ATP .99 .95 .86 .96 1.11 1.02 .98
Gtf2a2
KLA  ATP  ATP+KLA
 NM_001039519 general transcription factor II A, 2 (Gtf2a2), mRNA [NM_001039519] KLA .97 .99 .98 1.02 .86 .83 .74
ATP .99 .98 1.25 1.05 1.17 .98 .76
KLA/ATP .92 .92 1.17 .94 1.08 1.00 .77
Gtf2b
KLA  ATP  ATP+KLA
 NM_145546 general transcription factor IIB (Gtf2b), mRNA [NM_145546] KLA 2.06 1.99 1.46 1.18 .94 .88 .85
ATP 1.00 .93 1.09 1.23 2.23 2.17 1.20
KLA/ATP 1.92 1.96 2.20 1.95 2.26 2.78 1.44
Gtf2e1
KLA  ATP  ATP+KLA
 NM_028812 general transcription factor II E, polypeptide 1 (alpha subunit) (Gtf2e1), mRNA [NM_028812] KLA 1.19 1.16 .97 .85 .75 .89 .98
ATP .91 .85 .88 .53 .45 1.05 .94
KLA/ATP 1.05 1.03 .91 .63 .45 .75 .72
Gtf2e2
KLA  ATP  ATP+KLA
 NM_026584 general transcription factor II E, polypeptide 2 (beta subunit) (Gtf2e2), mRNA [NM_026584] KLA .89 .90 1.13 1.14 1.00 1.06 .99
ATP 1.02 .98 1.34 1.07 .81 1.65 1.22
KLA/ATP .88 1.01 1.43 1.08 1.01 1.33 1.03
Gtf2f1
KLA  ATP  ATP+KLA
 NM_133801 general transcription factor IIF, polypeptide 1 (Gtf2f1), mRNA [NM_133801] KLA 2.02 1.96 1.76 2.19 2.04 1.73 1.27
ATP .96 .80 .61 .69 1.46 2.44 1.47
KLA/ATP 1.64 1.50 1.33 1.32 1.77 2.63 2.15
Gtf2f2
KLA  ATP  ATP+KLA
 NM_026816 general transcription factor IIF, polypeptide 2 (Gtf2f2), mRNA [NM_026816] KLA 1.43 1.46 1.36 1.31 1.22 1.17 1.36
ATP 1.00 1.00 1.08 1.05 1.18 1.88 1.35
KLA/ATP 1.35 1.42 1.56 1.39 1.24 1.38 1.24
Gtf2h1
KLA  ATP  ATP+KLA
 NM_008186 general transcription factor II H, polypeptide 1 (Gtf2h1), mRNA [NM_008186] KLA .96 .91 .87 1.10 1.18 1.19 1.30
ATP 1.04 .96 1.16 1.24 1.93 1.49 1.38
KLA/ATP .88 .84 .93 1.15 2.20 1.65 1.38
Gtf2h2
KLA  ATP  ATP+KLA
 BC016231 general transcription factor II H, polypeptide 2, mRNA (cDNA clone MGC:28787 IMAGE:4488798), complete cds. [BC016231] KLA .77 .82 .79 .88 1.07 1.44 1.58
ATP 1.03 1.00 1.15 .96 .77 .97 1.42
KLA/ATP .82 .79 .85 .82 1.12 1.95 1.99
Gtf2h2
KLA  ATP  ATP+KLA
 NM_022011 general transcription factor II H, polypeptide 2 (Gtf2h2), mRNA [NM_022011] KLA .77 .82 .76 .74 .81 1.02 1.46
ATP 1.04 1.02 1.07 1.00 .60 .76 .96
KLA/ATP .71 .75 .73 .69 .52 .88 .91
Gtf2h3
KLA  ATP  ATP+KLA
 NM_181410 general transcription factor IIH, polypeptide 3 (Gtf2h3), mRNA [NM_181410] KLA 1.02 1.09 1.11 1.16 1.31 1.44 1.51
ATP .94 .97 .97 .95 .51 .70 1.43
KLA/ATP 1.00 1.06 1.05 1.12 .76 .82 1.32
Gtf2h4
KLA  ATP  ATP+KLA
 NM_010364 general transcription factor II H, polypeptide 4 (Gtf2h4), mRNA [NM_010364] KLA .96 1.08 .98 .99 .94 .88 .98
ATP 1.00 .98 .71 .69 .50 .77 .91
KLA/ATP 1.09 1.09 .78 .80 .56 .64 .57
Gtf2h5
KLA  ATP  ATP+KLA
 NM_181392 general transcription factor IIH, polypeptide 5 (Gtf2h5), mRNA [NM_181392] KLA 1.05 1.04 .95 1.00 1.01 .94 1.08
ATP 1.09 .98 1.38 1.23 1.20 .95 .96
KLA/ATP .90 1.02 1.47 1.23 1.13 .89 .92
Gtf2i
KLA  ATP  ATP+KLA
 AF017085 BAP-135 homolog (Diws1t) mRNA, complete cds. [AF017085] KLA .37 .32 .27 .21 .20 .34 .57
ATP 1.01 .79 .44 .37 .26 .14 .48
KLA/ATP .41 .29 .15 .14 .14 .13 .20
Gtf2i
KLA  ATP  ATP+KLA
 AK085902 16 days neonate heart cDNA, RIKEN full-length enriched library, clone:D830026O16 product:general transcription factor II I, full insert sequence. [AK085902] KLA .94 .89 .89 .85 .91 .90 .89
ATP 1.04 .85 .88 .87 .88 1.00 .94
KLA/ATP .95 .93 .82 .83 .84 .88 .76
Gtf2i
KLA  ATP  ATP+KLA
 NM_010365 general transcription factor II I (Gtf2i), transcript variant 2, mRNA [NM_010365] KLA .41 .39 .32 .25 .26 .42 .62
ATP .89 .72 .46 .41 .29 .20 .61
KLA/ATP .41 .33 .21 .23 .21 .19 .32
Gtf2ird1
KLA  ATP  ATP+KLA
 NM_020331 general transcription factor II I repeat domain-containing 1 (Gtf2ird1), transcript variant 1, mRNA [NM_020331] KLA .42 .39 .33 .39 .40 .46 .51
ATP .86 .81 1.17 1.02 .64 .86 .62
KLA/ATP .35 .36 .47 .40 .46 .66 .43
Mm.30344
1
KLA  ATP  ATP+KLA
 157951656 Unknown KLA .88 .91 .88 .95 .86 1.05 1.11
ATP .86 .78 1.35 1.07 1.00 .99 .96
KLA/ATP .87 .89 1.17 .98 1.03 .85 .91
Mm.31223
3
KLA  ATP  ATP+KLA
 149269666 Unknown KLA 1.09 1.05 1.09 .97 .85 .87 .88
ATP .92 1.01 1.10 1.32 1.22 1.01 .87
KLA/ATP 1.05 1.08 1.06 1.10 1.08 .89 .83
Mm.33273
5
KLA  ATP  ATP+KLA
 125625330 Unknown KLA .33 .30 .33 .39 .42 .46 .55
ATP .93 .94 1.52 1.18 .83 .75 .70
KLA/ATP .28 .30 .47 .40 .59 .45 .32
Mm.39142
7
KLA  ATP  ATP+KLA
 153792620 Unknown KLA 1.05 1.01 1.00 .97 1.04 1.01 .99
ATP .96 1.01 1.02 1.02 1.00 1.00 .97
KLA/ATP 1.08 1.01 1.06 1.02 1.03 1.00 1.00
Mnat1
KLA  ATP  ATP+KLA
 AK029174 0 day neonate head cDNA, RIKEN full-length enriched library, clone:4831405B13 product:menage a trois 1, full insert sequence. [AK029174] KLA 1.04 .95 .97 .96 .99 .99 1.09
ATP .98 .96 .98 1.01 1.01 .94 1.01
KLA/ATP .96 1.01 .98 1.01 1.00 .96 .87
Mnat1
KLA  ATP  ATP+KLA
 NM_008612 menage a trois 1 (Mnat1), mRNA [NM_008612] KLA 1.16 1.36 1.22 1.18 1.18 1.03 .97
ATP .95 .99 1.11 1.06 .70 .86 .78
KLA/ATP 1.22 1.25 1.37 1.29 .90 .67 .81
Taf1
KLA  ATP  ATP+KLA
 NM_001081008 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf1), mRNA [NM_001081008] KLA 1.04 1.02 1.01 .98 .93 .90 .84
ATP 1.05 1.07 1.15 .94 .79 .75 .91
KLA/ATP 1.04 1.13 1.23 .91 .79 .72 .79
Taf10
KLA  ATP  ATP+KLA
 NM_020024 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf10), mRNA [NM_020024] KLA .77 .81 .83 .74 .87 .89 1.21
ATP 1.02 1.12 1.01 1.39 1.06 .75 1.24
KLA/ATP .89 .90 .66 1.03 .78 .73 .97
Taf11
KLA  ATP  ATP+KLA
 NM_026836 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf11), mRNA [NM_026836] KLA 1.32 1.28 1.42 1.52 1.46 1.26 1.01
ATP 1.01 .91 1.07 .84 .86 1.49 .99
KLA/ATP 1.28 1.19 1.49 1.23 1.52 1.83 1.20
Taf12
KLA  ATP  ATP+KLA
 NM_025579 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf12), mRNA [NM_025579] KLA .92 .90 .91 .89 .96 1.25 1.46
ATP .96 1.00 1.12 1.27 1.05 1.36 1.81
KLA/ATP .89 .91 .99 1.01 1.07 1.66 2.32
Taf13
KLA  ATP  ATP+KLA
 NM_025444 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf13), mRNA [NM_025444] KLA 1.24 1.20 1.13 1.30 1.08 1.26 .93
ATP 1.11 1.00 1.22 1.07 1.08 1.35 1.02
KLA/ATP 1.06 1.12 1.70 1.24 1.24 1.24 .92
Taf15
KLA  ATP  ATP+KLA
 NM_027427 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf15), mRNA [NM_027427] KLA 1.51 1.56 1.95 1.33 1.25 1.30 1.28
ATP 1.13 1.16 1.56 1.05 2.10 1.43 1.03
KLA/ATP 1.60 1.68 2.71 1.79 1.63 1.16 1.08
Taf2
KLA  ATP  ATP+KLA
 NM_001081288 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf2), mRNA [NM_001081288] KLA 1.09 1.14 1.14 .97 1.02 1.00 1.07
ATP 1.02 1.07 .99 .77 .74 .94 1.05
KLA/ATP 1.09 1.03 .88 .77 .71 .92 .93
Taf3
KLA  ATP  ATP+KLA
 AK030878 adult male thymus cDNA, RIKEN full-length enriched library, clone:5830438I15 product:TAFII140 PROTEIN (FRAGMENT) homolog [Mus musculus], full insert sequence [AK030878] KLA .86 .96 .84 .84 .85 .88 1.04
ATP 1.10 1.11 1.09 .93 .84 .85 .85
KLA/ATP .98 .89 .85 .86 .88 .78 .71
Taf3
KLA  ATP  ATP+KLA
 NM_027748 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf3), mRNA [NM_027748] KLA 1.11 1.15 1.04 1.02 .95 1.10 1.39
ATP 1.05 1.11 1.07 1.20 1.03 1.27 1.40
KLA/ATP 1.15 1.12 1.06 1.12 .92 1.26 1.56
Taf4a
KLA  ATP  ATP+KLA
 NM_001081092 TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf4a), mRNA [NM_001081092] KLA .63 .66 .64 .71 .80 .93 .99
ATP 1.00 1.12 1.12 1.09 1.02 .85 .86
KLA/ATP .58 .64 .69 .74 .90 .87 .86
Taf4b
KLA  ATP  ATP+KLA
 XM_128905 gb|PREDICTED: Mus musculus TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf4b), mRNA [XM_128905] KLA 1.06 1.10 .93 .95 .94 .99 1.04
ATP .96 1.01 1.38 1.94 1.58 1.01 .97
KLA/ATP 1.04 1.00 1.10 1.41 1.29 1.17 .94
Taf5
KLA  ATP  ATP+KLA
 NM_177342 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf5), mRNA [NM_177342] KLA .80 .80 .82 .71 .78 1.08 1.11
ATP 1.03 1.10 1.18 .96 1.68 1.26 .98
KLA/ATP .79 .77 .80 .74 1.51 1.22 .92
Taf5l
KLA  ATP  ATP+KLA
 NM_133966 TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor (Taf5l), mRNA [NM_133966] KLA .94 .95 .93 .89 .87 .90 1.08
ATP 1.05 .96 .88 .92 1.92 1.61 1.37
KLA/ATP .91 .97 .94 .80 1.63 1.61 .96
Taf6
KLA  ATP  ATP+KLA
 NM_009315 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf6), mRNA [NM_009315] KLA .78 .83 .93 .84 .77 1.04 1.03
ATP 1.05 1.08 .94 1.09 .63 .71 .97
KLA/ATP .81 .83 .79 .82 .62 .78 1.01
Taf6l
KLA  ATP  ATP+KLA
 NM_146092 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor (Taf6l), mRNA [NM_146092] KLA .95 .90 .92 .80 .89 1.23 1.20
ATP 1.05 1.16 .96 1.18 .79 1.21 1.67
KLA/ATP 1.03 1.05 .83 1.00 .87 1.34 1.91
Taf7
KLA  ATP  ATP+KLA
 NM_011901 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf7), mRNA [NM_011901] KLA 1.95 1.89 1.72 1.55 1.59 1.73 1.50
ATP 1.01 .98 1.07 1.15 1.78 1.95 1.42
KLA/ATP 1.88 2.10 2.26 3.19 3.26 2.40 2.30
Taf7
KLA  ATP  ATP+KLA
 NM_175770 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf7), mRNA [NM_175770] KLA 1.26 1.24 1.21 1.12 1.06 1.17 1.00
ATP 1.07 1.14 1.02 .96 1.08 1.27 1.08
KLA/ATP 1.22 1.33 1.33 1.55 1.29 1.18 1.16
Taf7l
KLA  ATP  ATP+KLA
 NM_028958 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf7l), mRNA [NM_028958] KLA 1.05 1.04 .97 1.02 1.02 1.01 1.00
ATP .98 1.02 1.02 .99 1.06 1.02 1.05
KLA/ATP .96 1.00 .97 1.13 1.14 .97 1.00
Taf8
KLA  ATP  ATP+KLA
 NM_022015 TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorq (Taf8), mRNA [NM_022015] KLA .95 .84 .88 1.09 1.00 1.12 1.03
ATP .89 .72 .93 .60 1.23 1.51 .79
KLA/ATP .69 .80 1.01 .63 1.73 2.21 1.13
Taf9
KLA  ATP  ATP+KLA
 NM_001015889 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf9), transcript variant 3, mRNA [NM_001015889] KLA .98 .92 .89 .91 .81 .83 .92
ATP .96 .96 1.05 1.04 1.26 1.14 .78
KLA/ATP .89 .89 .89 .88 .99 1.04 .71
Taf9
KLA  ATP  ATP+KLA
 NM_027592 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf9), transcript variant 2, mRNA [NM_027592] KLA 1.21 1.32 1.31 1.15 1.24 1.40 1.61
ATP .96 .94 1.35 1.37 2.08 2.99 1.56
KLA/ATP 1.22 1.49 1.69 1.74 2.52 3.58 2.07
Taf9b
KLA  ATP  ATP+KLA
 NM_001001176 TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor (Taf9b), mRNA [NM_001001176] KLA .90 .98 .93 .89 .81 .75 .85
ATP 1.00 1.08 1.08 1.02 .80 .62 1.00
KLA/ATP .96 .94 .91 .92 .72 .62 .63
Tbp
KLA  ATP  ATP+KLA
 NM_013684 TATA box binding protein (Tbp), mRNA [NM_013684] KLA 1.27 1.33 1.42 1.17 1.23 1.20 1.22
ATP 1.07 1.21 1.01 .85 .93 1.04 1.14
KLA/ATP 1.38 1.40 1.13 1.11 .93 1.13 1.12
Tbpl1
KLA  ATP  ATP+KLA
 AK028621 10 days neonate skin cDNA, RIKEN full-length enriched library, clone:4732418P20 product:TATA box binding protein-like protein, full insert sequence [AK028621] KLA 1.03 1.11 .99 .98 .97 .88 .92
ATP .95 1.03 1.05 .94 .94 .96 1.09
KLA/ATP .98 .95 .99 .98 .98 1.03 1.01
Tbpl1
KLA  ATP  ATP+KLA
 NM_011603 TATA box binding protein-like 1 (Tbpl1), mRNA [NM_011603] KLA .68 .72 .72 .71 .76 .87 1.05
ATP .93 .97 .98 .89 1.05 .97 .85
KLA/ATP .67 .66 .74 .70 1.04 1.20 1.00
Tbpl2
KLA  ATP  ATP+KLA
 NM_199059 TATA box binding protein like 2 (Tbpl2), mRNA [NM_199059] KLA 1.01 1.10 .97 1.00 .92 .96 1.04
ATP 1.01 1.03 1.04 1.02 .95 1.00 1.02
KLA/ATP 1.04 .92 .83 1.06 1.03 1.02 .97