Gene/Proteome Database (LMPD)

LMPD ID
LMP000961
Gene ID
391013
Species
Homo sapiens (Human)
Gene Name
phospholipase A2, group IIC
Gene Symbol
PLA2G2C
Synonyms
-
Chromosome
1
Map Location
1p36.12

Proteins

putative inactive group IIC secretory phospholipase A2 precursor
Refseq ID NP_001099042
Protein GI 157743243
UniProt ID J3KMZ3
mRNA ID NM_001105572
Length 150
RefSeq Status PROVISIONAL
MLIATSFFLFFSSVVAAPTHSSFWQFQRRVKHITGRSAFFSYYGYGCYCGLGDKGIPVDDTDSPSSPSPYEKLKEFSCQPVLNSYQFHIVNGAVVCGCTLGPGASCHCRLKACECDKQSVHCFKESLPTYEKNFKQFSSQPRCGRHKPWC
sig_peptide: 1..16 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1780 peptide sequence: MLIATSFFLFFSSVVA

Gene Information

Entrez Gene ID
391013
Gene Name
phospholipase A2, group IIC
Gene Symbol
PLA2G2C
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0005509 IEA:InterPro F calcium ion binding
GO:0047498 IEA:Ensembl F calcium-dependent phospholipase A2 activity
GO:0016042 IEA:InterPro P lipid catabolic process
GO:0006644 IEA:InterPro P phospholipid metabolic process

KEGG Pathway Links

KEGG Pathway ID Description
hsa04975 Fat digestion and absorption
hsa04972 Pancreatic secretion
hsa04014 Ras signaling pathway
hsa04270 Vascular smooth muscle contraction

Domain Information

InterPro Annotations

Accession Description
IPR001211 Phospholipase A2
IPR016090 Phospholipase A2 domain
IPR013090 Phospholipase A2, active site

UniProt Annotations

Entry Information

Gene Name
phospholipase A2, group IIC
Protein Entry
J3KMZ3_HUMAN
UniProt ID
J3KMZ3
Species
Human

Comments

Comment Type Description
Catalytic Activity Phosphatidylcholine + H(2)O = 1- acylglycerophosphocholine + a carboxylate.
Caution The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Cofactor Note=Binds 1 calcium ion per subunit. ;
Similarity Belongs to the phospholipase A2 family.
Subcellular Location Secreted .

Identical and Related Proteins

Unique RefSeq proteins for LMP000961 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
157743243 RefSeq NP_001099042 150 putative inactive group IIC secretory phospholipase A2 precursor

Identical Sequences to LMP000961 proteins

Reference Database Accession Length Protein Name
GI:157743243 GenBank AEU43346.1 150 Sequence 95 from patent US 8052970

Related Sequences to LMP000961 proteins

Reference Database Accession Length Protein Name
GI:157743243 GenBank EHH14405.1 150 hypothetical protein EGK_00326, partial [Macaca mulatta]
GI:157743243 GenBank EHH49607.1 150 hypothetical protein EGM_00297, partial [Macaca fascicularis]
GI:157743243 RefSeq XP_004092316.1 211 PREDICTED: LOW QUALITY PROTEIN: putative inactive group IIC secretory phospholipase A2 [Nomascus leucogenys]
GI:157743243 RefSeq XP_002811432.3 277 PREDICTED: putative inactive group IIC secretory phospholipase A2 [Pongo abelii]
GI:157743243 RefSeq XP_010365045.1 286 PREDICTED: putative inactive group IIC secretory phospholipase A2 [Rhinopithecus roxellana]
GI:157743243 SwissProt Q5R387.3 149 RecName: Full=Putative inactive group IIC secretory phospholipase A2; AltName: Full=Phosphatidylcholine 2-acylhydrolase-like protein GIIC; Flags: Precursor [Homo sapiens]