Gene/Proteome Database (LMPD)

LMPD ID
LMP002352
Gene ID
Species
Mus musculus (Mouse)
Gene Name
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
Gene Symbol
Synonyms
-
Alternate Names
ATP synthase F(0) complex subunit C1, mitochondrial; ATPase protein 9; ATPase subunit c; ATP synthase proteolipid P1; ATP synthase lipid-binding protein, mitochondrial; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1
Chromosome
11
Map Location
11 D|11

Proteins

ATP synthase F(0) complex subunit C1, mitochondrial
Refseq ID NP_001154891
Protein GI 238637299
UniProt ID Q9CR84
mRNA ID NM_001161419
Length 136
RefSeq Status VALIDATED
MQTTKALLISPALIRSCTRGLIRPVSASLLSRPEAPSKQPSCSSSPLQVARREFQTSVISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
ATP synthase F(0) complex subunit C1, mitochondrial
Refseq ID NP_031532
Protein GI 31982497
UniProt ID Q9CR84
mRNA ID NM_007506
Length 136
RefSeq Status VALIDATED
Protein sequence is identical to GI:238637299 (mRNA isoform)
transit_peptide: 1..61 experiment: experimental evidence, no additional details recorded note: Mitochondrion; propagated from UniProtKB/Swiss-Prot (Q9CR84.1) calculated_mol_wt: 6610 peptide sequence: MQTTKALLISPALIRSCTRGLIRPVSASLLSRPEAPSKQPSCSSSPLQVARREFQTSVISR mat_peptide: 62..136 product: ATP synthase F(0) complex subunit C1, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9CR84.1) calculated_mol_wt: 7608 peptide sequence: DIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM transit_peptide: 1..61 experiment: experimental evidence, no additional details recorded note: Mitochondrion; propagated from UniProtKB/Swiss-Prot (Q9CR84.1) calculated_mol_wt: 6610 peptide sequence: MQTTKALLISPALIRSCTRGLIRPVSASLLSRPEAPSKQPSCSSSPLQVARREFQTSVISR mat_peptide: 62..136 product: ATP synthase F(0) complex subunit C1, mitochondrial experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9CR84.1) calculated_mol_wt: 7608 peptide sequence: DIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM

Gene Information

Entrez Gene ID
Gene Name
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
Gene Symbol
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005743 IDA:MGI C mitochondrial inner membrane
GO:0005753 ISS:UniProtKB C mitochondrial proton-transporting ATP synthase complex
GO:0005739 IDA:MGI C mitochondrion
GO:0045263 IEA:UniProtKB-KW C proton-transporting ATP synthase complex, coupling factor F(o)
GO:0015078 IEA:InterPro F hydrogen ion transmembrane transporter activity
GO:0008289 IEA:UniProtKB-KW F lipid binding
GO:0015991 IEA:InterPro P ATP hydrolysis coupled proton transport
GO:0015986 IEA:InterPro P ATP synthesis coupled proton transport

KEGG Pathway Links

KEGG Pathway ID Description
mmu05010 Alzheimer's disease
mmu05016 Huntington's disease
mmu05012 Parkinson's disease

Domain Information

InterPro Annotations

Accession Description
IPR000454 ATPase, F0 complex, subunit C
IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site
IPR002379 V-ATPase proteolipid subunit C-like domain

UniProt Annotations

Entry Information

Gene Name
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9)
Protein Entry
AT5G1_MOUSE
UniProt ID
Species
Mouse

Comments

Comment Type Description
Disease Note=This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease).
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element (By similarity). {ECO:0000250}.
Miscellaneous There are three genes which encode the mitochondrial ATP synthase proteolipid and they specify precursors with different import sequences but identical mature proteins. {ECO:0000305}.
Similarity Belongs to the ATPase C chain family. {ECO:0000305}.
Subcellular Location Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
Subunit F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68 (By similarity). {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP002352 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
238637299 RefSeq NP_001154891 136 ATP synthase F(0) complex subunit C1, mitochondrial

Identical Sequences to LMP002352 proteins

Reference Database Accession Length Protein Name
GI:238637299 GenBank AAH94664.1 136 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1 [Mus musculus]
GI:238637299 GenBank EDL16011.1 136 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1, isoform CRA_a [Mus musculus]
GI:238637299 GenBank EDL16012.1 136 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1, isoform CRA_a [Mus musculus]
GI:238637299 GenBank EDL16013.1 136 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 1, isoform CRA_a [Mus musculus]
GI:238637299 RefSeq NP_031532.2 136 ATP synthase F(0) complex subunit C1, mitochondrial [Mus musculus]
GI:238637299 SwissProt Q9CR84.1 136 RecName: Full=ATP synthase F(0) complex subunit C1, mitochondrial; AltName: Full=ATP synthase lipid-binding protein; AltName: Full=ATP synthase proteolipid P1; AltName: Full=ATPase protein 9; AltName: Full=ATPase subunit c; Flags: Precursor [Mus musculus]

Related Sequences to LMP002352 proteins

Reference Database Accession Length Protein Name
GI:238637299 DBBJ BAE39897.1 136 unnamed protein product [Mus musculus]
GI:238637299 GenBank AAA16434.1 136 H+ ATP synthase [Mus musculus]
GI:238637299 GenBank EDL02565.1 136 mCG134178 [Mus musculus]
GI:238637299 RefSeq XP_005368423.1 136 PREDICTED: ATP synthase lipid-binding protein, mitochondrial isoform X4 [Microtus ochrogaster]
GI:238637299 RefSeq XP_005368424.1 136 PREDICTED: ATP synthase lipid-binding protein, mitochondrial isoform X5 [Microtus ochrogaster]
GI:238637299 RefSeq XP_007631094.1 136 PREDICTED: ATP synthase F(0) complex subunit C1, mitochondrial [Cricetulus griseus]