Gene/Proteome Database (LMPD)

LMPD ID
LMP002656
Gene ID
109791
Species
Mus musculus (Mouse)
Gene Name
colipase, pancreatic
Gene Symbol
Clps
Synonyms
2200003J09Rik
Alternate Names
colipase
Chromosome
17
Map Location
17|17 B1

Proteins

colipase precursor
Refseq ID NP_079745
Protein GI 13384886
UniProt ID Q9CQC2
mRNA ID NM_025469
Length 113
RefSeq Status PROVISIONAL
MEKVLVLLLVSLLAVAYAAPGPRGLIINLEDGEICLNSMQCKSRCCQHDTILGIARCTHKAMENSECSPKTLYGIYYRCPCERGLTCEGDRSIIGAITNTNYGICLDSRRSKQ
sig_peptide: 1..18 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1945 peptide sequence: MEKVLVLLLVSLLAVAYA mat_peptide: 24..113 product: Colipase experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (Q9CQC2.1) calculated_mol_wt: 10039 peptide sequence: GLIINLEDGEICLNSMQCKSRCCQHDTILGIARCTHKAMENSECSPKTLYGIYYRCPCERGLTCEGDRSIIGAITNTNYGICLDSRRSKQ

Gene Information

Entrez Gene ID
109791
Gene Name
colipase, pancreatic
Gene Symbol
Clps
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0070062 IEA:Ensembl C extracellular vesicular exosome
GO:0008047 IEA:InterPro F enzyme activator activity
GO:0007586 IEA:UniProtKB-KW P digestion
GO:0016042 IEA:UniProtKB-KW P lipid catabolic process

KEGG Pathway Links

KEGG Pathway ID Description
ko04975 Fat digestion and absorption
mmu04975 Fat digestion and absorption

REACTOME Pathway Links

REACTOME Pathway ID Description
5893445 Digestion of dietary lipid
5893902 Retinoid metabolism and transport

Domain Information

InterPro Annotations

Accession Description
IPR001981 Colipase
IPR017914 Colipase, C-terminal
IPR017913 Colipase, N-terminal
IPR017915 Colipase, conserved site

UniProt Annotations

Entry Information

Gene Name
colipase, pancreatic
Protein Entry
COL_MOUSE
UniProt ID
Q9CQC2
Species
Mouse

Comments

Comment Type Description
Function Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
Function Enterostatin has a biological activity as a satiety signal. {ECO:0000250}.
Similarity Belongs to the colipase family. {ECO:0000255|PROSITE- ProRule:PRU00674}.
Subcellular Location Secreted.
Subunit Forms a 1:1 stoichiometric complex with pancreatic lipase. {ECO:0000255|PROSITE-ProRule:PRU00674}.
Tissue Specificity Expressed by the pancreas.

Identical and Related Proteins

Unique RefSeq proteins for LMP002656 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
13384886 RefSeq NP_079745 113 colipase precursor

Identical Sequences to LMP002656 proteins

Reference Database Accession Length Protein Name
GI:13384886 DBBJ BAC25769.1 113 unnamed protein product [Mus musculus]
GI:13384886 GenBank AAL40730.1 113 colipase [Mus musculus]
GI:13384886 GenBank AAL40731.1 113 colipase [Mus musculus]
GI:13384886 GenBank AAH42935.1 113 Colipase, pancreatic [Mus musculus]
GI:13384886 GenBank EDL22580.1 113 colipase, pancreatic [Mus musculus]
GI:13384886 SwissProt Q9CQC2.1 113 RecName: Full=Colipase; Flags: Precursor [Mus musculus]

Related Sequences to LMP002656 proteins

Reference Database Accession Length Protein Name
GI:13384886 DBBJ BAB31505.1 113 unnamed protein product [Mus musculus]
GI:13384886 GenBank AAA40943.1 112 colipase [Rattus norvegicus]
GI:13384886 GenBank AAA20505.1 112 colipase [Rattus norvegicus]
GI:13384886 RefSeq NP_037271.1 112 colipase precursor [Rattus norvegicus]
GI:13384886 RefSeq XP_008770933.1 112 PREDICTED: colipase isoform X1 [Rattus norvegicus]
GI:13384886 SwissProt P17084.2 112 RecName: Full=Colipase; Flags: Precursor [Rattus norvegicus]