Gene/Proteome Database (LMPD)

LMPD ID
LMP004479
Gene ID
207182
Species
Mus musculus (Mouse)
Gene Name
gamma-glutamyltransferase 7
Gene Symbol
Ggt7
Synonyms
1110017C11Rik; 6330563L03Rik; Ggtl3
Alternate Names
gamma-glutamyltransferase 7; GGT 7; mFLJ00311 protein; glutathione hydrolase 7; gamma-glutamyltranspeptidase 7; gamma-glutamyltransferase-like 3
Chromosome
2
Map Location
2 H1|2
EC Number
2.3.2.2

Proteins

gamma-glutamyltransferase 7
Refseq ID NP_659035
Protein GI 224994186
UniProt ID Q99JP7
mRNA ID NM_144786
Length 662
RefSeq Status VALIDATED
MAAENEASQESALGAYSPVDYMSITSFPRLPEDEPAPAAPLRGRKDEDAFLGDPDTDPDSFLKSARLQRLPSSSSEMGSQDGSPLRETRKDPFSAAAAECSCRQDGLTVIVTACLTFATGVTVALVMQIYFGDPQIFQQGAVVTDASSCTALGMEVLSKQGSSVDAAVAAALCLGIVAPHSSGLGGGGVMLVHDIRRNESHLIDFRESAPGALREEALQRSWDTKPGLLVGVPGMVKGLHEAHQLYGRLPWSQVLAFAAAVAQDGFNVTHDLAHALAEQLPPNASDRFLDTFLPLGHPPLPGSLLRRPDLAEVLDILGTSGPAAFYNGGNLTLEMVAEAQHAGGVITEEDFSNYSALTEKPVCGVYRGHLVLSPPPPHTGPALISALNILEGFNLTSLVSREQALHWVAETLKIALALASRLGDPVYDSTITESMDDMLSKVEAANFRGHISDSQAAPAPLLPVYELDGAPTAAQVLVMGPDDFIVAMVSSLNRPFGSGLLTPSGILLNSQMLDFSWPNRTANHSAPSLENSVQPGKRPLSFLLPTVVRPAEGLCGTYLALGANGAARGLSGLTQVLLNVLTLNRNLSDSLARGRLHPDLQSNLLQVDSEFTEEEIEFLEARGHHVEKVDVLSWVHGSRRTNTFIIGVKDPRSPDAAGATIL

Gene Information

Entrez Gene ID
207182
Gene Name
gamma-glutamyltransferase 7
Gene Symbol
Ggt7
Species
Mus musculus

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0003840 IEA:UniProtKB-EC F gamma-glutamyltransferase activity
GO:0036374 IEA:UniProtKB-EC F glutathione hydrolase activity
GO:0006750 IEA:UniProtKB-KW P glutathione biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
mmu00460 Cyanoamino acid metabolism
mmu00480 Glutathione metabolism
mmu01100 Metabolic pathways
mmu00430 Taurine and hypotaurine metabolism

Domain Information

InterPro Annotations

Accession Description
IPR000101 Gamma-glutamyltranspeptidase
IPR029055 Nucleophile aminohydrolases, N-terminal

UniProt Annotations

Entry Information

Gene Name
gamma-glutamyltransferase 7
Protein Entry
GGT7_MOUSE
UniProt ID
Q99JP7
Species
Mouse

Comments

Comment Type Description
Catalytic Activity A (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid.
Catalytic Activity Glutathione + H(2)O = L-cysteinylglycine + L- glutamate.
Function Cleaves glutathione conjugates. {ECO:0000250}.
Pathway Sulfur metabolism; glutathione metabolism.
Similarity Belongs to the gamma-glutamyltransferase family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Subunit Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Interacts with FAM57A (By similarity). {ECO:0000250}.

Identical and Related Proteins

Unique RefSeq proteins for LMP004479 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
224994186 RefSeq NP_659035 662 gamma-glutamyltransferase 7

Identical Sequences to LMP004479 proteins

Reference Database Accession Length Protein Name
GI:224994186 DBBJ BAC27672.1 662 unnamed protein product [Mus musculus]
GI:224994186 SwissProt Q99JP7.2 662 RecName: Full=Gamma-glutamyltransferase 7; Short=GGT 7; AltName: Full=Gamma-glutamyltransferase-like 3; AltName: Full=Gamma-glutamyltranspeptidase 7; AltName: Full=Glutathione hydrolase 7; Contains: RecName: Full=Gamma-glutamyltransferase 7 heavy chain; Contains: RecName: Full=Gamma-glutamyltransferase 7 light chain; Flags: Precursor [Mus musculus]

Related Sequences to LMP004479 proteins

Reference Database Accession Length Protein Name
GI:224994186 GenBank AAH05772.1 662 Gamma-glutamyltransferase 7 [Mus musculus]
GI:224994186 GenBank EDL85916.1 662 gamma-glutamyltransferase-like 3, isoform CRA_b [Rattus norvegicus]
GI:224994186 RefSeq NP_569107.2 662 gamma-glutamyltransferase 7 [Rattus norvegicus]
GI:224994186 RefSeq XP_003501178.1 662 PREDICTED: LOW QUALITY PROTEIN: gamma-glutamyltransferase 7 [Cricetulus griseus]
GI:224994186 RefSeq XP_005363136.1 662 PREDICTED: gamma-glutamyltransferase 7 [Microtus ochrogaster]
GI:224994186 SwissProt Q99MZ4.2 662 RecName: Full=Gamma-glutamyltransferase 7; Short=GGT 7; AltName: Full=Gamma-glutamyltransferase-like 3; AltName: Full=Gamma-glutamyltranspeptidase 7; AltName: Full=Glutathione hydrolase 7; Contains: RecName: Full=Gamma-glutamyltransferase 7 heavy chain; Contains: RecName: Full=Gamma-glutamyltransferase 7 light chain; Flags: Precursor [Rattus norvegicus]