Gene/Proteome Database (LMPD)

LMPD ID
LMP006614
Gene ID
729330
Species
Homo sapiens (Human)
Gene Name
otoconin 90
Gene Symbol
OC90
Synonyms
PLA2L
Alternate Names
otoconin-90; phospholipase A2 homolog
Chromosome
8
Map Location
8q24.22

Proteins

otoconin-90 precursor
Refseq ID NP_001073868
Protein GI 223029412
UniProt ID Q02509
mRNA ID NM_001080399
Length 477
RefSeq Status VALIDATED
MIAFLLTSVLMIPHAGGHPLDTPHLPQELPPGLPNNINITFFSGMFKNVESVAEIFDCLGPHFTWLQAVFTNFPVLIQFVNGMKCVAGLCPRDFEDYGCTCRFEMEGLPVDESDSCCFQHRRCYEEAAEMDCLQDPAKLSTEVNCVSKKIICESKDNCEHLLCTCDKAAIECLARSSLNSSLNLLDTSFCLAQTPETTIKEDLTTLLPRVVPVEPTDTSLTALSGEEAGHDQEGVGAARATSPPGSAEIVATRVTAKIVTLVPAGIKSLGLAVSSVENDPEETTEKACDRFTFLHLGSGDNMQVMPQLGEMLFCLTSRCPEEFESYGCYCGQEGRGEPRDDLDRCCLSHHCCLEQVRRLGCLLERLPWSPVVCVDHTPKCGGQSLCEKLLCACDQTAAECMTSASFNQSLKSPSRLGCPGQPAACEDSLHPVPAAPTLGSSSEEDSEEDPPQEDLGRAKRFLRKSLGPLGIGPLHGR
sig_peptide: 1..17 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1771 peptide sequence: MIAFLLTSVLMIPHAGG

Gene Information

Entrez Gene ID
729330
Gene Name
otoconin 90
Gene Symbol
OC90
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0005509 IEA:InterPro F calcium ion binding
GO:0004623 IEA:InterPro F phospholipase A2 activity
GO:0016042 IEA:InterPro P lipid catabolic process
GO:0006644 IEA:InterPro P phospholipid metabolic process

Domain Information

InterPro Annotations

Accession Description
IPR001211 Phospholipase A2
IPR013090 Phospholipase A2, active site
IPR016090 Phospholipase A2 domain

UniProt Annotations

Entry Information

Gene Name
otoconin 90
Protein Entry
OC90_HUMAN
UniProt ID
Q02509
Species
Human

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q02509-1; Sequence=Displayed; Name=2; IsoId=Q02509-2; Sequence=VSP_040320;
Domain Consists of 3 PA2-type domains.
Function It is unlikely that this protein has phospholipase A2 activity.
Sequence Caution Sequence=CAA78662.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence= ;
Similarity Belongs to the phospholipase A2 family.
Subcellular Location Secreted .
Subunit Interacts with OTOL1.

Identical and Related Proteins

Unique RefSeq proteins for LMP006614 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
223029412 RefSeq NP_001073868 477 otoconin-90 precursor

Identical Sequences to LMP006614 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP006614 proteins

Reference Database Accession Length Protein Name
GI:223029412 DBBJ BAG60230.1 477 unnamed protein product [Homo sapiens]
GI:223029412 EMBL CAA78662.1 689 unnamed protein product [Human endogenous retrovirus]
GI:223029412 GenBank EAW92140.1 689 HERV-H LTR-associating 1, isoform CRA_b [Homo sapiens]
GI:223029412 RefSeq XP_003830144.1 477 PREDICTED: otoconin-90 [Pan paniscus]
GI:223029412 RefSeq XP_004047585.1 477 PREDICTED: otoconin-90 [Gorilla gorilla gorilla]
GI:223029412 SwissProt Q02509.3 493 RecName: Full=Otoconin-90; Short=Oc90; AltName: Full=Phospholipase A2 homolog; Flags: Precursor [Homo sapiens]