Gene/Proteome Database (LMPD)

LMPD ID
LMP006651
Gene ID
200150
Species
Homo sapiens (Human)
Gene Name
phospholipase D family, member 5
Gene Symbol
PLD5
Synonyms
PLDC
Alternate Names
inactive phospholipase D5; inactive PLD 5; inactive choline phosphatase 5; inactive phosphatidylcholine-hydrolyzing phospholipase D5
Chromosome
1
Map Location
1q43

Proteins

inactive phospholipase D5 isoform 1
Refseq ID NP_689879
Protein GI 307775443
UniProt ID Q8N7P1
mRNA ID NM_152666
Length 536
RefSeq Status VALIDATED
MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSSLFKLKPLSNKTATDDTGGKDPRNV
inactive phospholipase D5 isoform 2
Refseq ID NP_001182740
Protein GI 307775435
UniProt ID Q8N7P1
mRNA ID NM_001195811
Length 474
RefSeq Status VALIDATED
MSQQKCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSACQGQRLFEKLLQLTSQNIEIKLVSDVTADSKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSSLFKLKPLSNKTATDDTGGKDPRNV
inactive phospholipase D5 isoform 3
Refseq ID NP_001182741
Protein GI 307775437
UniProt ID Q8N7P1
mRNA ID NM_001195812
Length 328
RefSeq Status VALIDATED
MNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKRTYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVRNNRSIIKQLKDVFERDWYSPYAKTLQPTKQPNCSSLFKLKPLSNKTATDDTGGKDPRNV

Gene Information

Entrez Gene ID
200150
Gene Name
phospholipase D family, member 5
Gene Symbol
PLD5
Species
Homo sapiens

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0003824 IEA:InterPro F catalytic activity

Domain Information

InterPro Annotations

Accession Description
IPR001736 Phospholipase D/Transphosphatidylase

UniProt Annotations

Entry Information

Gene Name
phospholipase D family, member 5
Protein Entry
PLD5_HUMAN
UniProt ID
Q8N7P1
Species
Human

Comments

Comment Type Description
Alternative Products Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q8N7P1-1; Sequence=Displayed; Name=2; IsoId=Q8N7P1-2; Sequence=VSP_025725; Note=No experimental confirmation available.; Name=3; IsoId=Q8N7P1-3; Sequence=VSP_025724; Name=4; IsoId=Q8N7P1-4; Sequence=VSP_025726, VSP_025727;
Caution In contrast to other members of the family, it lacks the conserved active sites, suggesting that it has no phospholipase activity.
Sequence Caution Sequence=AAI01374.1; Type=Erroneous initiation; Evidence= ; Sequence=AAI01375.1; Type=Erroneous initiation; Evidence= ; Sequence=AAI01376.1; Type=Erroneous initiation; Evidence= ;
Similarity Belongs to the phospholipase D family.
Similarity Contains 2 PLD phosphodiesterase domains.
Subcellular Location Membrane ; Single-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP006651 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
307775443 RefSeq NP_689879 536 inactive phospholipase D5 isoform 1
307775435 RefSeq NP_001182740 474 inactive phospholipase D5 isoform 2
307775437 RefSeq NP_001182741 328 inactive phospholipase D5 isoform 3

Identical Sequences to LMP006651 proteins

Reference Database Accession Length Protein Name
GI:307775437 DBBJ BAC03722.1 328 unnamed protein product [Homo sapiens]
GI:307775435 DBBJ BAH12060.1 474 unnamed protein product [Homo sapiens]
GI:307775435 GenBank AAS91020.1 474 PLDc protein [Homo sapiens]
GI:307775437 GenBank ABA66983.1 328 Sequence 2625 from patent US 6943241
GI:307775437 GenBank EAW70113.1 328 phospholipase D family, member 5, isoform CRA_b [Homo sapiens]
GI:307775443 GenBank AGX46729.1 536 Sequence 7 from patent US 8541183
GI:307775443 RefSeq XP_006711815.1 536 PREDICTED: inactive phospholipase D5 isoform X1 [Homo sapiens]
GI:307775443 SwissProt Q8N7P1.2 536 RecName: Full=Inactive phospholipase D5; Short=Inactive PLD 5; AltName: Full=Inactive choline phosphatase 5; AltName: Full=Inactive phosphatidylcholine-hydrolyzing phospholipase D5; AltName: Full=PLDc [Homo sapiens]

Related Sequences to LMP006651 proteins

Reference Database Accession Length Protein Name
GI:307775437 DBBJ BAC05230.1 444 unnamed protein product [Homo sapiens]
GI:307775437 GenBank AAS91020.1 474 PLDc protein [Homo sapiens]
GI:307775437 GenBank EAW70111.1 444 phospholipase D family, member 5, isoform CRA_a [Homo sapiens]
GI:307775437 GenBank EAW70112.1 444 phospholipase D family, member 5, isoform CRA_a [Homo sapiens]
GI:307775437 GenBank ABP29744.1 444 Sequence 4759 from patent US 7193069
GI:307775443 GenBank JAB45330.1 536 inactive phospholipase D5 isoform 1 [Callithrix jacchus]
GI:307775435 GenBank AGX46729.1 536 Sequence 7 from patent US 8541183
GI:307775443 RefSeq XP_001092989.1 536 PREDICTED: inactive phospholipase D5 isoform 3 [Macaca mulatta]
GI:307775443 RefSeq XP_514306.2 536 PREDICTED: inactive phospholipase D5 isoform X1 [Pan troglodytes]
GI:307775435 RefSeq XP_514306.2 536 PREDICTED: inactive phospholipase D5 isoform X1 [Pan troglodytes]
GI:307775437 RefSeq NP_001182740.1 474 inactive phospholipase D5 isoform 2 [Homo sapiens]
GI:307775435 RefSeq NP_689879.2 536 inactive phospholipase D5 isoform 1 [Homo sapiens]
GI:307775435 RefSeq XP_003308884.1 474 PREDICTED: inactive phospholipase D5 isoform X2 [Pan troglodytes]
GI:307775443 RefSeq XP_005539715.1 536 PREDICTED: inactive phospholipase D5 isoform X1 [Macaca fascicularis]
GI:307775435 RefSeq XP_006711815.1 536 PREDICTED: inactive phospholipase D5 isoform X1 [Homo sapiens]
GI:307775443 RefSeq XP_007988143.1 536 PREDICTED: inactive phospholipase D5 isoform X1 [Chlorocebus sabaeus]
GI:307775443 RefSeq XP_010383011.1 536 PREDICTED: inactive phospholipase D5 isoform X1 [Rhinopithecus roxellana]
GI:307775435 SwissProt Q8N7P1.2 536 RecName: Full=Inactive phospholipase D5; Short=Inactive PLD 5; AltName: Full=Inactive choline phosphatase 5; AltName: Full=Inactive phosphatidylcholine-hydrolyzing phospholipase D5; AltName: Full=PLDc [Homo sapiens]