Gene/Proteome Database (LMPD)
Proteins
Sps19p | |
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Refseq ID | NP_014197 |
Protein GI | 99030931 |
UniProt ID | P32573 |
mRNA ID | NM_001183040 |
Length | 292 |
MNTANTLDGKFVTEGSWRPDLFKGKVAFVTGGAGTICRVQTEALVLLGCKAAIVGRDQERTEQAAKGISQLAKDKDAVLAIANVDVRNFEQVENAVKKTVEKFGKIDFVIAGAAGNFVCDFANLSPNAFKSVVDIDLLGSFNTAKACLKELKKSKGSILFVSATFHYYGVPFQGHVGAAKAGIDALAKNLAVELGPLGIRSNCIAPGAIDNTEGLKRLAGKKYKEKALAKIPLQRLGSTRDIAESTVYIFSPAASYVTGTVLVVDGGMWHLGTYFGHELYPEALIKSMTSKL |
Gene Information
Gene Ontology (GO Annotations)
GO ID | Source | Type | Description |
---|---|---|---|
GO:0005782 | IDA:SGD | C | peroxisomal matrix |
GO:0008670 | IDA:SGD | F | 2,4-dienoyl-CoA reductase (NADPH) activity |
GO:0030437 | IMP:SGD | P | ascospore formation |
GO:0009062 | IDA:SGD | P | fatty acid catabolic process |
KEGG Pathway Links
BIOCYC Pathway Links
BIOCYC Pathway ID | Description |
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PWY-7337 | 10-cis-heptadecenoyl-CoA degradation |
PWY-7337 | 10-cis-heptadecenoyl-CoA degradation (yeast) |
PWY-7338 | 10-trans-heptadecenoyl-CoA degradation (reductase-dependent) |
PWY-7338 | 10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast) |
PWY-6837 | fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent) |
PWY-7307 | oleate beta-oxidation (reductase-dependent) |
PWY-7307 | oleate beta-oxidation (reductase-dependent, yeast) |
Domain Information
UniProt Annotations
Entry Information
Comments
Comment Type | Description |
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Catalytic Activity | Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH |
Catalytic Activity | Trans-2,3-didehydroacyl-CoA + NADP(+) = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH. {ECO:0000269|PubMed:9268358}. |
Developmental Stage | Sequentially activated during the process of meiosis and spore formation. |
Function | Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Dispensable for growth and sporulation on solid acetate and oleate media, but is essential for these processes to occur on petroselineate. |
Induction | By oleate. Transcription is regulated by the transcription factors PIP2, OAF1 and ADR1. Weakly induced during sporulation in diploid cells. {ECO:0000269|PubMed:11170837, ECO:0000269|PubMed:9268358, ECO:0000269|PubMed:9427398}. |
Sequence Caution | Sequence=AAA62403.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAT93138.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA55506.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA96103.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Sequence Caution | Sequence=AAA62403.1; Type=Erroneous initiation; Evidence= ; Sequence=AAT93138.1; Type=Erroneous initiation; Evidence= ; Sequence=CAA55506.1; Type=Erroneous initiation; Evidence= ; Sequence=CAA96103.1; Type=Erroneous initiation; Evidence= ; |
Similarity | Belongs to the short-chain dehydrogenases/reductases (SDR) family |
Similarity | Belongs to the short-chain dehydrogenases/reductases (SDR) family. {ECO:0000305}. |
Subcellular Location | Peroxisome . |
Subcellular Location | Peroxisome {ECO:0000269|PubMed:9268358}. |
Subunit | Homodimer |
Subunit | Homodimer. {ECO:0000269|PubMed:9268358}. |
Identical and Related Proteins
Unique RefSeq proteins for LMP007167 (as displayed in Record Overview)
Identical Sequences to LMP007167 proteins
Reference | Database | Accession | Length | Protein Name |
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Related Sequences to LMP007167 proteins
Reference | Database | Accession | Length | Protein Name |
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