Gene/Proteome Database (LMPD)

LMPD ID
LMP007348
Gene ID
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
Inn1p
Gene Symbol
Synonyms
-
Chromosome
XIV

Proteins

Inn1p
Refseq ID NP_014247
Protein GI 6324177
UniProt ID P53901
mRNA ID NM_001182990
Length 409
MSEEVWNGNQGILSVYVSKARDLPNLNKLDKQNVMLRLRIAHMTRASNTLHRAGQNPVFHYLEKFDITPEIKPLMYVEVYCDRRKKSPLPIGRCEIDLLNAIRADPKEGYCTWYELKRSGDEFAGTIFIELTFTPKVPRLNRDDLNKEMDRLDSSMAMRPIPPLPTESEYDYVHGSTMRQITPQCVSTSHEDKDEGQPYRNGNVFSMSSKSDTAVLANSNDPIILPPTFSASMGTTSTLETNDTAISNTSNTKFHFANLRKLKEKINIFKNPDSSTNNCQNESNKVDIEALQKAIGVTSLSYDEDDDDDDENDAFYSSSHRVSHNYNQPPLPPIPTRDDMSNYSSSRNTPLVRRDRPSRLDSSSPNSHPHPSGLNSPKLPPLPTTSNSNFNSRKNSMSPTRKRPPPRLS

Gene Information

Entrez Gene ID
Gene Name
Inn1p
Gene Symbol
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0044697 IPI:SGD C HICS complex
GO:0000142 IDA:SGD C cellular bud neck contractile ring
GO:0030234 IGI:SGD F enzyme regulator activity
GO:0005543 ISS:SGD F phospholipid binding
GO:0000917 IMP:SGD P barrier septum assembly
GO:0051276 IMP:SGD P chromosome organization
GO:0000281 IMP:SGD P mitotic cytokinesis
GO:0007067 IEA:UniProtKB-KW P mitotic nuclear division
GO:0050790 IGI:GOC P regulation of catalytic activity

Domain Information

InterPro Annotations

Accession Description
IPR000008 C2 domain

UniProt Annotations

Entry Information

Gene Name
Inn1p
Protein Entry
INN1_YEAST
UniProt ID
Species
Yeast (S288c)

Comments

Comment Type Description
Domain The C2 domain is essential for membrane ingression during cytokinesis, but not for recruitment to the actomyosin ring
Domain The C2 domain is essential for membrane ingression during cytokinesis, but not for recruitment to the actomyosin ring. {ECO:0000269|PubMed:18344988}.
Function Required for the ingression of the plasma membrane into the bud neck at the end of cytokinesis, leading to the separation of the mother and daughter cells. Stimulates the synthesis of the primary septum (PS) by CHS2. {ECO:0000269|PubMed:18344988, ECO:0000269|PubMed:19528296, ECO:0000269|PubMed:19707790}.
Interaction Q05080:HOF1; NbExp=5; IntAct=EBI-28955, EBI-5412; P80667:PEX13; NbExp=2; IntAct=EBI-28955, EBI-13206;
Similarity Belongs to the INN1/fic1 family
Similarity Belongs to the INN1/fic1 family. {ECO:0000305}.
Similarity Contains 1 C2 domain
Similarity Contains 1 C2 domain. {ECO:0000305}.
Subcellular Location Bud neck {ECO:0000269|PubMed:18344988, ECO:0000269|PubMed:19528296, ECO:0000269|PubMed:19707790, ECO:0000269|PubMed:20442249}. Note=Localizes at the contractile actinomyosin ring at the end of cytokinesis. Recruitment to the bud neck requires either CYK2 or CYK3.
Subunit Interacts with CYK2, CYK3 and IQG1. {ECO:0000269|PubMed:18344988, ECO:0000269|PubMed:19528296, ECO:0000269|PubMed:19707790}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007348 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6324177 RefSeq NP_014247 409 Inn1p

Identical Sequences to LMP007348 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007348 proteins

Reference Database Accession Length Protein Name