Gene/Proteome Database (LMPD)

LMPD ID
LMP007403
Gene ID
856791
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
glycerol-1-phosphatase HOR2
Gene Symbol
GPP2
Synonyms
HOR2
Alternate Names
glycerol-1-phosphatase HOR2
Chromosome
V
EC Number
3.1.3.21

Proteins

glycerol-1-phosphatase HOR2
Refseq ID NP_010984
Protein GI 398364483
UniProt ID P40106
mRNA ID NM_001178953
Length 250
RefSeq Status PROVISIONAL
MGLTTKPLSLKVNAALFDVDGTIIISQPAIAAFWRDFGKDKPYFDAEHVIQVSHGWRTFDAIAKFAPDFANEEYVNKLEAEIPVKYGEKSIEVPGAVKLCNALNALPKEKWAVATSGTRDMAQKWFEHLGIRRPKYFITANDVKQGKPHPEPYLKGRNGLGYPINEQDPSKSKVVVFEDAPAGIAAGKAAGCKIIGIATTFDLDFLKEKGCDIIVKNHESIRVGGYNAETDEVEFIFDDYLYAKDDLLKW

Gene Information

Entrez Gene ID
856791
Gene Name
glycerol-1-phosphatase HOR2
Gene Symbol
GPP2
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:UniProtKB-KW C cytoplasm
GO:0000121 IDA:SGD F glycerol-1-phosphatase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0044262 IDA:SGD P cellular carbohydrate metabolic process
GO:0016311 IDA:GOC P dephosphorylation
GO:0006114 IMP:SGD P glycerol biosynthetic process
GO:0006970 IDA:SGD P response to osmotic stress

KEGG Pathway Links

KEGG Pathway ID Description
sce00561 Glycerolipid metabolism
sce01100 Metabolic pathways

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY3O-48 glycerol biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR006439 HAD hydrolase, subfamily IA
IPR023214 HAD-like domain
IPR023198 Phosphoglycolate phosphatase, domain 2

UniProt Annotations

Entry Information

Gene Name
glycerol-1-phosphatase HOR2
Protein Entry
GPP2_YEAST
UniProt ID
P40106
Species
Yeast (S288c)

Comments

Comment Type Description
Biophysicochemical Properties Kinetic parameters: KM=3.9 mM for (DL)-glycerol 3-phosphate {ECO:0000269|PubMed:8662716}; Vmax=46 umol/min/mg enzyme {ECO:0000269|PubMed:8662716}; pH dependence: Optimum pH is 6.5 {ECO:0000269|PubMed:8662716};
Catalytic Activity Glycerol 1-phosphate + H(2)O = glycerol + phosphate. {ECO:0000269|PubMed:8662716}.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000305|PubMed:8662716};
Function Glycerol-1-phosphate phosphohydrolase involved in glycerol biosynthesis. Plays a role in osmoadaptation. {ECO:0000269|PubMed:8662716}.
Induction By osmotic stress (at protein level). {ECO:0000269|PubMed:8662716}.
Miscellaneous Present with 5000 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}.
Similarity Belongs to the HAD-like hydrolase superfamily. DOG/GPP family. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Subunit Monomer. {ECO:0000269|PubMed:8662716}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007403 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
398364483 RefSeq NP_010984 250 glycerol-1-phosphatase HOR2

Identical Sequences to LMP007403 proteins

Reference Database Accession Length Protein Name
GI:398364483 GenBank AGA48851.1 250 Sequence 58 from patent US 8324455
GI:398364483 GenBank AGB63004.1 250 Sequence 8 from patent US 8288137
GI:398364483 GenBank AHH78186.1 250 Sequence 8 from patent US 8629243
GI:398364483 GenBank EWG86554.1 250 Hor2p [Saccharomyces cerevisiae R008]
GI:398364483 GenBank EWG91451.1 250 Hor2p [Saccharomyces cerevisiae P301]
GI:398364483 GenBank EWG96474.1 250 Hor2p [Saccharomyces cerevisiae R103]

Related Sequences to LMP007403 proteins

Reference Database Accession Length Protein Name
GI:398364483 DBBJ GAA22894.1 250 K7_Hor2p [Saccharomyces cerevisiae Kyokai no. 7]
GI:398364483 GenBank EDN63036.1 250 hyperosmolarity-responsive protein [Saccharomyces cerevisiae YJM789]
GI:398364483 GenBank EDV08892.1 250 DL-glycerol-3-phosphatase [Saccharomyces cerevisiae RM11-1a]
GI:398364483 GenBank EHN07587.1 250 Hor2p [Saccharomyces cerevisiae x Saccharomyces kudriavzevii VIN7]
GI:398364483 GenBank EWH18817.1 250 Hor2p [Saccharomyces cerevisiae P283]
GI:398364483 gnl McCuskerlabDuke 250 Hor2p [Saccharomyces cerevisiae YJM993]