Gene/Proteome Database (LMPD)

LMPD ID
LMP007496
Gene ID
853113
Species
Saccharomyces cerevisiae S288c (Yeast (S288c))
Gene Name
dolichyl-phosphate-mannose-protein mannosyltransferase PMT6
Gene Symbol
PMT6
Synonyms
-
Chromosome
VII
EC Number
2.4.1.109 ;

Proteins

dolichyl-phosphate-mannose-protein mannosyltransferase PMT6
Refseq ID NP_011715
Protein GI 6321638
UniProt ID P42934
mRNA ID NM_001181328
Length 759
MSKAKGTGFSSIDTEDENLRERYVNQPKANASDIQDEQLDCFEQLEEKHRTKKNEEYTALKILRDVIGPLLLTITSFYLRFQHIDQNNYVVWDEAHFGKFGSYYIKHEYYHDVHPPLGKMLIALSEWMAGFDGQFDFSSNNAYPENVNFKLMRQFNATFGALCTPVAFFTAKWMGFNYFTVYLIATMVTLEHSYIVLSKFILLDSMLLFFSMTTFACMIKLYTLRKQQMTKKWSLWMLLTGLSIGCVCSVKWVGLFITVVVGLYTCIELFLLYCDKELPRIKYYKHWLIRIINLIVIPFLIYLYCFKIHFVLLYKSGTGDSTTNTLFQINLEGTQIEAGPRDVAFGSELTIRSHGLSPNLLHSHIQVYPEGSGQRQITGYGFADSNNVWKFEFSRSSGLELDQNGTLNGKIIPITDGVEVRLSHKNTGSNLHSHDVPSHVSRGNYEVSGYGSQSVGDEKDDWIVEIVKQMDSPNPVYSNENSTILHPVSTFFRLRHKVLGCYLASTGLTYPAWGFKQAEIVCKDSWSRRDKSTWWNVEDHWNHNLETAEDYVPPKSNFWTDFILTNFAMASSNNALVPDEDKYDSLSSDAWEWPTLHKGLRMCSWAGYITRYYLMGSPFNTWISTVSLIIFPFIILFILYRWRRQTLYLSDDQIWQITIQGIFPFISWMTHYLPFAMMGRVTYVHHYVPALYFAMLVFGFVLDFTLTRVHWMVKYPIYLSLFGGCIYIYNLFAPICQGMHGDKAEYLPLQWLSTWDIAP

Gene Information

Entrez Gene ID
853113
Gene Name
dolichyl-phosphate-mannose-protein mannosyltransferase PMT6
Gene Symbol
PMT6
Species
Saccharomyces cerevisiae S288c

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0004169 ISA:SGD F dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0006493 IMP:SGD P protein O-linked glycosylation
GO:0035269 IMP:SGD P protein O-linked mannosylation

KEGG Pathway Links

KEGG Pathway ID Description
ko00514 Other types of O-glycan biosynthesis
sce00514 Other types of O-glycan biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR003342 Glycosyl transferase, family 39
IPR027005 Glycosyltransferase 39 like
IPR016093 MIR_motif

UniProt Annotations

Entry Information

Gene Name
dolichyl-phosphate-mannose-protein mannosyltransferase PMT6
Protein Entry
PMT6_YEAST
UniProt ID
P42934
Species
Yeast (S288c)

Comments

Comment Type Description
Catalytic Activity Dolichyl D-mannosyl phosphate + protein = dolichyl phosphate + O-D-mannosylprotein. {ECO:0000250|UniProtKB:P33775, ECO:0000303|PubMed:18182384, ECO:0000303|PubMed:9184828}.
Disruption Phenotype Affects GAS1 and GGP1 O-mannosylation
Disruption Phenotype Affects GAS1 and GGP1 O-mannosylation. {ECO:0000269|PubMed:18182384, ECO:0000269|PubMed:9184828}.
Function Protein O-mannosyltransferase involved in O- glycosylation which is essential for cell wall rigidity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. {ECO:0000250|UniProtKB:P33775, ECO:0000303|PubMed:18182384, ECO:0000303|PubMed:9184828}.
Pathway Protein modification; protein glycosylation
Pathway Protein modification; protein glycosylation. {ECO:0000305}.
Similarity Belongs to the glycosyltransferase 39 family
Similarity Belongs to the glycosyltransferase 39 family. {ECO:0000305}.
Similarity Contains 3 MIR domains. {ECO:0000255|PROSITE- ProRule:PRU00131}.
Subcellular Location Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P33775}; Multi-pass membrane protein {ECO:0000255}.
Subunit May form an hetodimer with PMT4
Subunit May form an hetodimer with PMT4. {ECO:0000303|PubMed:9184828}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007496 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
6321638 RefSeq NP_011715 759 dolichyl-phosphate-mannose-protein mannosyltransferase PMT6

Identical Sequences to LMP007496 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP007496 proteins

Reference Database Accession Length Protein Name