LIPID MAPS

LMPD ID

LMP007506

Gene ID

Species

Saccharomyces cerevisiae S288c (Yeast (S288c))

Gene Name

Pbn1p

Gene Symbol

PBN1

Synonyms

-

Chromosome

III

Pbn1p
Refseq ID	NP_009878
Protein GI	6319797
UniProt ID	P25580
mRNA ID	NM_001178697
Length	416
MVTRHRVTVLYNAPEDIGNHMRQNDTHLTVRGGSGVVLQQRWLLERTGSLDKSFTRITWRPRADLARSLSVIENELSAGFSVYSNSSDVPERFITNPVYNSFHSEKFDIEQYLPPEVDLNLSWNPEDFTYDISVEPTQIQIVEYRLLKQGEEFTIARVKDEKLEVGVFFVDASDESDVDIGGIRCNWRMDDGKMERCQKTSLLYKQGHIAYNHSTTTTSLYLNEPIGLHPKIMIDLTDFEERPKCMYLMHLQLPLELFIDKFQSSPLLLFGEDDLELPEYSLRDKAWGSESIFELKAGTMNEVTLHTRYIEPSNNKGDKLEVSFDPEVILACDTGDNKVSRNPFYKKGLGYESLFTDDTTFRHLNSTTLLVPIPRPDTKDYSKIKNGTLLCLLISIIYIFSKVFGNNKKKRSVKRE

Entrez Gene ID

Gene Name

Pbn1p

Gene Symbol

PBN1

Species

Saccharomyces cerevisiae S288c

GO ID	Source	Type	Description
GO:0005783	IDA:SGD	C	endoplasmic reticulum
GO:0005789	IEA:InterPro	C	endoplasmic reticulum membrane
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0030433	IMP:SGD	P	ER-associated ubiquitin-dependent protein catabolic process
GO:0006506	IMP:SGD	P	GPI anchor biosynthetic process
GO:0097502	IMP:GOC	P	mannosylation
GO:0016485	IMP:SGD	P	protein processing

KEGG Pathway ID	Description
ko00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
sce01100	Metabolic pathways

Accession	Description
IPR013233	Glycosylphosphatidylinositol-mannosyltransferase I, PIG-X/PBN1

Gene Name

Pbn1p

Protein Entry

PBN1_YEAST

UniProt ID

Species

Yeast (S288c)

Comment Type	Description
Function	Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Aids the autocatalytic processing of PRB1. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14. {ECO:0000269\|PubMed:15635094, ECO:0000269\|PubMed:16418276, ECO:0000269\|PubMed:9649520}.
Miscellaneous	Present with 4930 molecules/cell in log phase SD medium
Miscellaneous	Present with 4930 molecules/cell in log phase SD medium. {ECO:0000269\|PubMed:14562106}.
Pathway	Glycolipid biosynthesis; glycosylphosphatidylinositol- anchor biosynthesis.
Ptm	N-glycosylated
Ptm	N-glycosylated. {ECO:0000269\|PubMed:9649520}.
Similarity	Belongs to the PIGX family
Similarity	Belongs to the PIGX family. {ECO:0000305}.
Subcellular Location	Endoplasmic reticulum membrane ; Single-pass type III membrane protein .
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269\|PubMed:9649520}; Single-pass type III membrane protein {ECO:0000269\|PubMed:9649520}.