LIPID MAPS

LMPD ID

LMP007903

Gene ID

Species

Caenorhabditis elegans (C. elegans)

Gene Name

Protein ELO-4

Gene Symbol

elo-4

Synonyms

CELE_C40H1.4

Chromosome

III

EC Number

2.3.1.199

Protein ELO-4
Refseq ID	NP_499056
Protein GI	17552588
UniProt ID	Q03574
mRNA ID	NM_066655
Length	291
MELAEFWNDLNTFTIYGPNHTDMTTKYKYSYHFPGEQVADPQYWTILFQKYWYHSITISVLYFILIKVIQKFMENRKPFTLKYPLILWNGALAAFSIIATLRFSIDPLRSLYAEGFYKTLCYSCNPTDVAAFWSFAFALSKIVELGDTMFIILRKRPLIFLHYYHHAAVLIYTVHSGAEHTAAGRFYILMNYFAHSLMYTYYTVSAMGYRLPKWVSMTVTTVQTTQMLAGVGITWMVYKVKTEYKLPCQQSVANLYLAFVIYVTFAILFIQFFVKAYIIKSSKKSKSVKNE

Entrez Gene ID

Gene Name

Protein ELO-4

Gene Symbol

elo-4

Species

Caenorhabditis elegans

GO ID	Source	Type	Description
GO:0030176	ISS:UniProtKB	C	integral component of endoplasmic reticulum membrane
GO:0016740	IEA:UniProtKB-KW	F	transferase activity
GO:0006633	IEA:UniProtKB-UniPathway	P	fatty acid biosynthetic process

REACTOME Pathway ID	Description
5653424	Activation of gene expression by SREBF (SREBP)
5652674	Fatty Acyl-CoA Biosynthesis
5652529	Fatty acid, triacylglycerol, and ketone body metabolism
5652491	Metabolism
5652530	Metabolism of lipids and lipoproteins
5653425	Regulation of cholesterol biosynthesis by SREBP (SREBF)
5652683	Synthesis of very long-chain fatty acyl-CoAs
5652675	Triglyceride Biosynthesis

Accession	Description
IPR002076	ELO family

Gene Name

Protein ELO-4

Protein Entry

ELO4_CAEEL

UniProt ID

Species

C. elegans

Comment Type	Description
Catalytic Activity	A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
Function	Could be implicated in synthesis of very long chain fatty acids
Function	Could be implicated in synthesis of very long chain fatty acids. {ECO:0000250}.
Pathway	Lipid metabolism; fatty acid biosynthesis.
Similarity	Belongs to the ELO family
Similarity	Belongs to the ELO family. {ECO:0000305}.
Subcellular Location	Membrane ; Multi-pass membrane protein .
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.