LIPID MAPS

LMPD ID

LMP007903

Gene ID

Species

Caenorhabditis elegans (C. elegans)

Gene Name

Protein ELO-4

Gene Symbol

elo-4

Synonyms

CELE_C40H1.4

Chromosome

III

EC Number

2.3.1.199

Protein ELO-4
Refseq ID	NP_499056
Protein GI	17552588
UniProt ID	Q03574
mRNA ID	NM_066655
Length	291
MELAEFWNDLNTFTIYGPNHTDMTTKYKYSYHFPGEQVADPQYWTILFQKYWYHSITISVLYFILIKVIQKFMENRKPFTLKYPLILWNGALAAFSIIATLRFSIDPLRSLYAEGFYKTLCYSCNPTDVAAFWSFAFALSKIVELGDTMFIILRKRPLIFLHYYHHAAVLIYTVHSGAEHTAAGRFYILMNYFAHSLMYTYYTVSAMGYRLPKWVSMTVTTVQTTQMLAGVGITWMVYKVKTEYKLPCQQSVANLYLAFVIYVTFAILFIQFFVKAYIIKSSKKSKSVKNE

Entrez Gene ID

Gene Name

Protein ELO-4

Gene Symbol

elo-4

Species

Caenorhabditis elegans

GO ID	Source	Type	Description
GO:0030176	ISS:UniProtKB	C	integral component of endoplasmic reticulum membrane
GO:0016740	IEA:UniProtKB-KW	F	transferase activity
GO:0006633	IEA:UniProtKB-UniPathway	P	fatty acid biosynthetic process

REACTOME Pathway ID	Description
5653424	Activation of gene expression by SREBF (SREBP)
5652529	Fatty acid, triacylglycerol, and ketone body metabolism
5652674	Fatty Acyl-CoA Biosynthesis
5652491	Metabolism
5652530	Metabolism of lipids and lipoproteins
5653425	Regulation of cholesterol biosynthesis by SREBP (SREBF)
5652683	Synthesis of very long-chain fatty acyl-CoAs
5652675	Triglyceride Biosynthesis

Accession	Description
IPR002076	ELO family

Gene Name

Protein ELO-4

Protein Entry

ELO4_CAEEL

UniProt ID

Species

C. elegans

Comment Type	Description
Catalytic Activity	A very-long-chain acyl-CoA + malonyl-CoA = CoA + a very-long-chain 3-oxoacyl-CoA + CO(2).
Function	Could be implicated in synthesis of very long chain fatty acids
Function	Could be implicated in synthesis of very long chain fatty acids. {ECO:0000250}.
Pathway	Lipid metabolism; fatty acid biosynthesis.
Similarity	Belongs to the ELO family
Similarity	Belongs to the ELO family. {ECO:0000305}.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Subcellular Location	Membrane ; Multi-pass membrane protein .