Gene/Proteome Database (LMPD)

LMPD ID
LMP007946
Gene ID
174140
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein ART-1
Gene Symbol
art-1
Synonyms
CELE_C15F1.6
Alternate Names
Protein ART-1
Chromosome
II
EC Number
1.3.1.93

Proteins

Protein ART-1
Refseq ID NP_495430
Protein GI 17531783
UniProt ID Q9N5Y2
mRNA ID NM_063029
Length 308
RefSeq Status REVIEWED
MSGILEVYDAKRTDNLIITLEGISGSETIKAIKKRIAQKKLKLTEERQALRVEPKGKPLADDQKLSDLGLSSQKAVLYVRDLGPQIAWKTVFMAEYAGPLFVYPLFYLRPTFIYGQAAVNATMHPAVQIAFFAWSFHYAKRLFETQFIHRFGNSTMPQFNLVKNCSYYWGFAAFVAYFVNHPLFTPPAFGDLQVYFGLAGFVISEFGNLSIHILLRNLRPAGTRERRIPKPDGNPLSLLFNYVSCPNYTYEVASWIFFSIMVQSLPAIIFTTAGFAQMAIWAQGKHRNYLKEFPDYPKNRKAIVPFVL

Gene Information

Entrez Gene ID
174140
Gene Name
Protein ART-1
Gene Symbol
art-1
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005737 IEA:InterPro C cytoplasm
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016627 IEA:InterPro F oxidoreductase activity, acting on the CH-CH group of donors
GO:0006633 IEA:UniProtKB-UniPathway P fatty acid biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
cel01040 Biosynthesis of unsaturated fatty acids
cel00062 Fatty acid elongation
cel01212 Fatty acid metabolism

REACTOME Pathway Links

REACTOME Pathway ID Description
5652683 Synthesis of very long-chain fatty acyl-CoAs

Domain Information

InterPro Annotations

Accession Description
IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
IPR000626 Ubiquitin-like
IPR029071 Ubiquitin-related domain

UniProt Annotations

Entry Information

Gene Name
Protein ART-1
Protein Entry
TECR_CAEEL
UniProt ID
Q9N5Y2
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity A very-long-chain acyl-CoA + NADP(+) = a very- long-chain trans-2,3-dehydroacyl-CoA + NADPH.
Function Reduces trans-2,3-acyl-CoA to acyl-CoA of long and very long chain fatty acids. {ECO:0000250}.
Pathway Lipid metabolism; fatty acid biosynthesis.
Similarity Belongs to the steroid 5-alpha reductase family. {ECO:0000305}.
Similarity Contains 1 ubiquitin-like domain. {ECO:0000255|PROSITE-ProRule:PRU00214}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP007946 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17531783 RefSeq NP_495430 308 Protein ART-1

Identical Sequences to LMP007946 proteins

Reference Database Accession Length Protein Name
GI:17531783 EMBL CCD64616.1 308 Protein ART-1 [Caenorhabditis elegans]
GI:17531783 SwissProt Q9N5Y2.1 308 RecName: Full=Probable very-long-chain enoyl-CoA reductase art-1 [Caenorhabditis elegans]

Related Sequences to LMP007946 proteins

Reference Database Accession Length Protein Name
GI:17531783 EMBL CAP30391.2 329 Protein CBR-ART-1 [Caenorhabditis briggsae]
GI:17531783 GenBank EFP07719.1 308 CRE-ART-1 protein [Caenorhabditis remanei]
GI:17531783 GenBank EGT55808.1 308 CBN-ART-1 protein [Caenorhabditis brenneri]
GI:17531783 GenBank ETN69804.1 309 trans-2,3-enoyl-CoA reductase [Necator americanus]
GI:17531783 RefSeq XP_002630463.1 308 C. briggsae CBR-ART-1 protein [Caenorhabditis briggsae]
GI:17531783 RefSeq XP_003113807.1 308 CRE-ART-1 protein [Caenorhabditis remanei]