Gene/Proteome Database (LMPD)

LMPD ID
LMP008008
Gene ID
178985
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein FUT-8
Gene Symbol
fut-8
Synonyms
CELE_C10F3.6
Chromosome
V

Proteins

Protein FUT-8
Refseq ID NP_504555
Protein GI 32567172
UniProt ID G5EFE7
mRNA ID NM_072154
Length 559
RefSeq Status REVIEWED
MLKCIAAVGTVVWMTMFLFLYSQLSNNQSGGDSIRAWRQTKEAIDKLQEQNEDLKSILEKERQERNDQHKKIMEQSHQLPPNPENPSLPKPEPVKEIISKPSILGPVQQEVQKRMLDDRIREMFYLLHSQTIENSTKILLETQMISLMGLSAQLEKLEGSEEERFKQRTAITQRIFKSIEKLQNPKACSEAKTLVCNLDKECGFGCQLHHVTYCAITAFATQRMMVLKRDGSSWKYSSHGWTSVFKKLSKCSFDEAVGNTEAKPFAEPSPARVVSLGIVDSLITKPTFLPQAVPEQLLESLTSLHSHPPAFFVGTFISYLMRFNSATQEKLDKALKSIPLDKGPIVGLQIRRTDKVGTEAAFHALKEYMEWTEIWFKVEEKRQGKPLERRIFIASDDPTVVPEAKNDYPNYEVYGSTEIAKTAQLNNRYTDASLMGVITDIYILSKVNYLVCTFSSQVCRMGYELRQPSGADDGSKFHSLDDIYYFGGQQAHEVIVIEDHIAQNNKEIDLKVGDKVGIAGNHWNGYSKGTNRQTYKEGVFPSYKVVNDWRKFKFEALLD

Gene Information

Entrez Gene ID
178985
Gene Name
Protein FUT-8
Gene Symbol
fut-8
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0032580 IEA:UniProtKB-SubCell C Golgi cisterna membrane
GO:0016021 IEA:InterPro C integral component of membrane
GO:0046921 IDA:WormBase F alpha-(1->6)-fucosyltransferase activity
GO:0008424 IEA:UniProtKB-EC F glycoprotein 6-alpha-L-fucosyltransferase activity
GO:0036065 IDA:GOC P fucosylation
GO:0006487 IDA:WormBase P protein N-linked glycosylation
GO:0033578 IEA:InterPro P protein glycosylation in Golgi

Domain Information

InterPro Annotations

Accession Description
IPR015827 Alpha1_6FUT_euk
IPR027350 GT23_dom
IPR001452 SH3_domain

UniProt Annotations

Entry Information

Gene Name
Protein FUT-8
Protein Entry
G5EFE7_CAEEL
UniProt ID
G5EFE7
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity GDP-beta-L-fucose + N(4)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-beta-D-mannosyl- (1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D- glucosaminyl)asparagine = GDP + N(4)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-(N-acetyl-beta-D- glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6))-beta-D-mannosyl- (1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-(alpha-L-fucosyl- (1->6))-N-acetyl-beta-D-glucosaminyl)asparagine.
Function Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the glycosyltransferase 23 family.
Subcellular Location Golgi apparatus, Golgi stack membrane .

Identical and Related Proteins

Unique RefSeq proteins for LMP008008 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
32567172 RefSeq NP_504555 559 Protein FUT-8

Identical Sequences to LMP008008 proteins

Reference Database Accession Length Protein Name
GI:32567172 EMBL CAD54736.1 559 core alpha-6-fucosyltransferase [Caenorhabditis elegans]
GI:32567172 EMBL CCD64126.1 559 Protein FUT-8 [Caenorhabditis elegans]

Related Sequences to LMP008008 proteins

Reference Database Accession Length Protein Name
GI:32567172 EMBL CAI59573.1 556 alpha 1,6 fucosyltransferase [Caenorhabditis briggsae]
GI:32567172 EMBL CAP29285.3 559 Protein CBR-FUT-8 [Caenorhabditis briggsae]
GI:32567172 GenBank EFP11174.1 560 CRE-FUT-8 protein [Caenorhabditis remanei]
GI:32567172 GenBank EGT47213.1 560 CBN-FUT-8 protein [Caenorhabditis brenneri]
GI:32567172 PIR - 818 hypothetical protein C10F3.6 - Caenorhabditis elegans [Caenorhabditis elegans]
GI:32567172 RefSeq XP_003112653.1 560 CRE-FUT-8 protein [Caenorhabditis remanei]