Gene/Proteome Database (LMPD)

LMPD ID
LMP008058
Gene ID
182392
Species
Caenorhabditis elegans (C. elegans)
Gene Name
Protein C08B11.8
Gene Symbol
C08B11.8
Synonyms
CELE_C08B11.8
Chromosome
II
EC Number
2.4.1.267

Proteins

Protein C08B11.8
Refseq ID NP_495685
Protein GI 17531619
UniProt ID Q09226
mRNA ID NM_063284
Length 503
MKERIKDKAWRPQFIKLNNPDTSKKIVSQKSKKPEIVDLSSPGNNDLVTISILCVLLCFQLAISLNPHSGESQPPMYGDYEAQRHWMEITVNLPIEQWYLNGTHNDLLYWGLDYPPITAYHHYLLGVISNKINKKWVELTTSRGYESIAHKLFMRLSAIIPFYIFYLPPLIFYFTRSKKMSPILYALALLYPSLLVIDNGHFQYNSISLGLFLATYMFLTKNFTIIGSILFVAALNYKQMELYHALPVFVFILARSINKTQLFNSFRRILTIGLFVVGTFLIIWLPFLLTGTAKDVIIRVFPFNRGLYEDKVASFWCAFSFILKRLPLQSVQIYISTALVLAGSAPSLLVLFLRPTEKQFRISLTATGLSFFLFSFHVHEKTILLAAVPALLLISEYTSLVIWFLNITNISIFSLCVKDNFALSLSFFFAYFVVSYAYTAPRKISHILTILIGFAICILELYGPSNQRFPHIYQLANAFFSCVHFIYFLLYLSFASFEKTKKE

Gene Information

Entrez Gene ID
182392
Gene Name
Protein C08B11.8
Gene Symbol
C08B11.8
Species
Caenorhabditis elegans

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005789 IEA:InterPro C endoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016758 IEA:InterPro F transferase activity, transferring hexosyl groups
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation

KEGG Pathway Links

KEGG Pathway ID Description
cel01100 Metabolic pathways
cel00510 N-Glycan biosynthesis
ko00510 N-Glycan biosynthesis

REACTOME Pathway Links

REACTOME Pathway ID Description
5652982 Asparagine N-linked glycosylation
5652981 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
5652580 Metabolism of proteins
5652867 Post-translational protein modification

Domain Information

InterPro Annotations

Accession Description
IPR004856 Glycosyl transferase, ALG6/ALG8

UniProt Annotations

Entry Information

Gene Name
Protein C08B11.8
Protein Entry
ALG6_CAEEL
UniProt ID
Q09226
Species
C. elegans

Comments

Comment Type Description
Catalytic Activity Dolichyl beta-D-glucosyl phosphate + D-Man- alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha- (1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->6))- D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D- GlcNAc-diphosphodolichol = D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)- D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man- alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->6))-D-Man-alpha- (1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc- diphosphodolichol + dolichyl phosphate.
Function Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity)
Function Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). {ECO:0000250}.
Pathway Protein modification; protein glycosylation.
Similarity Belongs to the ALG6/ALG8 glucosyltransferase family
Similarity Belongs to the ALG6/ALG8 glucosyltransferase family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein .
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP008058 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
17531619 RefSeq NP_495685 503 Protein C08B11.8

Identical Sequences to LMP008058 proteins

Reference Database Accession Length Protein Name

Related Sequences to LMP008058 proteins

Reference Database Accession Length Protein Name