Gene/Proteome Database (LMPD)

LMPD ID
LMP009047
Gene ID
41369
Species
Drosophila melanogaster (Drosophila)
Gene Name
CG6728 gene product from transcript CG6728-RB
Gene Symbol
ninaG
Synonyms
CG6728; Dmel\CG6728; NinaG
Alternate Names
CG6728-PA; CG6728-PB; ninaG; ninaG-PA; ninaG-PB
Chromosome
3R
Map Location
86E5-86E5
EC Number
1.-.-.-

Proteins

ninaG, isoform A
Refseq ID NP_650070
Protein GI 24645930
UniProt ID Q9VGP2
mRNA ID NM_141813
Length 597
RefSeq Status REVIEWED
MGMKFQKILVLAGIVIGFLSIIVVLAGTLLKNSVPNVLAPVERHFAFDYVIVGGGTGGSTLTSLLAKNSNGSVLLIEAGGQFGLLSRIPLLTTFQQKGINDWSFLSVPQKHSSRGLIERRQCLPRGKGLGGSANLNYMLHFDGHGPDFDSWRDHHNLSDWSWAQMRSFMAAAKPKNPDMLEIPRRYSKLTEALEEAQAQFAYKDWIFRRSLYNIRNGLRHSVVQQFLNPVIHHSNLRLLPDALVKRIQLAPSPFLQATSILVGIKDEENREKEFSIEVRRELILCAGAYQTPQLLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDHFNLPLFVSMGVTGPTLNQNTLLNPMTLINYLSSGSGPLGNFGVLGNVVSYGGLGAPPYGITFFGAGAIDESALMSISNFKGPAFRALFPRYYNSSQEGFVVISSCLQPKSRGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAALHPRIHWPRVQECSNFGPFERDFFDNRPSDQYLECLMRHVGLGSHHPGGTCALGSVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWILKSELQAGDSK
ninaG, isoform B
Refseq ID NP_001247047
Protein GI 386765577
UniProt ID Q9VGP2
mRNA ID NM_001260118
Length 581
RefSeq Status REVIEWED
MGMKFQKILVLAGIVIGFLSIIVVLAGTLLKNSVPNVLAPVERHFAFDYVIVGGGTGGSTLTSLLAKNSNGSVLLIEAGGQFGLLSRIPLLTTFQQKGINDWSFLSVPQKHSSRGLIERRQCLPRGKGLGGSANLNYMLHFDGHGPDFDSWRDHHNLSDWSWAQMRSFMAAAKPKNPDMLEIPRRYSKLTEALEEAQAQFAYKDWIFRRSLYNIRNGLRHSVVQQFLNPVIHHSNLRLLPDALVKRIQLAPSPFLQATSILVGIKDEENREKEFSIELLMASGIGDVSALKKLGIPAQHSLPLVGHNLHDHFNLPLFVSMGVTGPTLNQNTLLNPMTLINYLSSGSGPLGNFGVLGNVVSYGGLGAPPYGITFFGAGAIDESALMSISNFKGPAFRALFPRYYNSSQEGFVVISSCLQPKSRGSVGLLNRHMRRNPLIDPNYLSSEEDVACTISAIRSAVELVNSTAFAALHPRIHWPRVQECSNFGPFERDFFDNRPSDQYLECLMRHVGLGSHHPGGTCALGSVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWILKSELQAGDSK

Gene Information

Entrez Gene ID
41369
Gene Name
CG6728 gene product from transcript CG6728-RB
Gene Symbol
ninaG
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005576 IEA:UniProtKB-KW C extracellular region
GO:0008812 IEA:InterPro F choline dehydrogenase activity
GO:0050660 IEA:InterPro F flavin adenine dinucleotide binding
GO:0016491 IMP:UniProtKB F oxidoreductase activity
GO:0006066 IEA:InterPro P alcohol metabolic process
GO:0050896 IEA:UniProtKB-KW P response to stimulus
GO:0001523 IMP:UniProtKB P retinoid metabolic process
GO:0046154 IMP:UniProtKB P rhodopsin metabolic process
GO:0006810 IMP:UniProtKB P transport
GO:0007601 IMP:UniProtKB P visual perception

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-7043 11-cis-3-hydroxyretinal biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR012132 Glucose-methanol-choline oxidoreductase
IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal
IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal

UniProt Annotations

Entry Information

Gene Name
CG6728 gene product from transcript CG6728-RB
Protein Entry
NINAG_DROME
UniProt ID
Q9VGP2
Species
Drosophila

Comments

Comment Type Description
Cofactor Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
Function Oxidoreductase involved in biosynthesis of 3- hydroxyretinal, a chromophore for rhodopsin Rh1. Not responsible for the initial hydroxylation of the retinal ring but rather acts in a subsequent step in chromophore production. May catalyze the conversion of (3R)-3-hydroxyretinol to the 3S enantiomer. {ECO:0000269|PubMed:15640158, ECO:0000269|PubMed:16464863}.
Sequence Caution Sequence=AAF54634.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Similarity Belongs to the GMC oxidoreductase family. {ECO:0000305}.
Subcellular Location Secreted {ECO:0000305}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009047 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24645930 RefSeq NP_650070 597 ninaG, isoform A
386765577 RefSeq NP_001247047 581 ninaG, isoform B

Identical Sequences to LMP009047 proteins

Reference Database Accession Length Protein Name
GI:386765577 GenBank AAM50678.1 581 GH24640p [Drosophila melanogaster]
GI:24645930 gnl FlyBase 597 ninaG, isoform A [Drosophila melanogaster]
GI:386765577 gnl FlyBase 581 ninaG, isoform B [Drosophila melanogaster]
GI:386765577 SwissProt Q9VGP2.2 581 RecName: Full=Neither inactivation nor afterpotential protein G; Flags: Precursor [Drosophila melanogaster]

Related Sequences to LMP009047 proteins

Reference Database Accession Length Protein Name
GI:24645930 GenBank AAM50678.1 581 GH24640p [Drosophila melanogaster]
GI:386765577 GenBank EDV49525.1 595 GG17223 [Drosophila erecta]
GI:24645930 GenBank EDV49525.1 595 GG17223 [Drosophila erecta]
GI:386765577 GenBank EDW96919.1 597 GE24624 [Drosophila yakuba]
GI:386765577 gnl FlyBase 597 ninaG, isoform A [Drosophila melanogaster]
GI:24645930 gnl FlyBase 581 ninaG, isoform B [Drosophila melanogaster]
GI:386765577 RefSeq NP_650070.1 597 ninaG, isoform A [Drosophila melanogaster]
GI:24645930 RefSeq XP_001980567.1 595 GG17223 [Drosophila erecta]
GI:386765577 RefSeq XP_001980567.1 595 GG17223 [Drosophila erecta]
GI:386765577 RefSeq XP_002097207.1 597 GE24624 [Drosophila yakuba]
GI:24645930 RefSeq NP_001247047.1 581 ninaG, isoform B [Drosophila melanogaster]
GI:24645930 SwissProt Q9VGP2.2 581 RecName: Full=Neither inactivation nor afterpotential protein G; Flags: Precursor [Drosophila melanogaster]