Gene/Proteome Database (LMPD)

LMPD ID
LMP009151
Gene ID
326193
Species
Drosophila melanogaster (Drosophila)
Gene Name
Alpha 3 glucosyltransferase
Gene Symbol
Alg10
Synonyms
alg10; CG32076; CG7624; Dmel\CG32076
Chromosome
3L
Map Location
68A9-68A9

Proteins

alpha 3 glucosyltransferase
Refseq ID NP_729680
Protein GI 24662563
UniProt ID Q8T8L8
mRNA ID NM_168449
Length 449
RefSeq Status REVIEWED
MNGSWKLILPVGFVLYSLPLFLRVNGTSDYVIDEEFHIPQGLAFCRKEFDVWDPKITTFPGLYLIALLLNPLSLCTVTGLRMLSLAGAGINILLLYKIRRRILAGSGGNSYAAHEAITMSVLPPLYFFSHLYYTDTLSLTMVLLFYNYWQQEAHLPAAVFGAASVLMRQTNIVWVCMATGMTVLDTLVNQCARTGRVPKENVRLMGKELWLQLVSSPQLLCNCILSILAKCCFYASIILPFVGFLFINGSIVVGDKSAHEASLHVPQLFYFAIFAAGFGISNTIRQFRPAAELIRRNRVLSLLALLLILVVVHLNTEVHPYLLADNRHYTFYIWSRLYGRFWWFRYAMAPAYLLSICVLFCGLRHMPESFKLMFPLSLFLVLCFQRLLELRYFLVPYILFRLNTRHTRKGYAEWLELGAHLLLNVATFYVYFTKEFYWKNYRTPQRIIW

Gene Information

Entrez Gene ID
326193
Gene Name
Alpha 3 glucosyltransferase
Gene Symbol
Alg10
Species
Drosophila melanogaster

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IEA:UniProtKB-KW C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0016758 IEA:InterPro F transferase activity, transferring hexosyl groups
GO:0006486 IEA:UniProtKB-UniPathway P protein glycosylation

Domain Information

InterPro Annotations

Accession Description
IPR016900 Alg10

UniProt Annotations

Entry Information

Gene Name
Alpha 3 glucosyltransferase
Protein Entry
Q8T8L8_DROME
UniProt ID
Q8T8L8
Species
Drosophila

Comments

Comment Type Description
Catalytic Activity Dolichyl beta-D-glucosyl phosphate + D-Glc- alpha-(1->3)-D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha- (1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)- (D-Man-alpha-(1->2)-D-Man-alpha-(1->6))-D-Man-alpha-(1->6)]-D-Man- beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol = D- Glc-alpha-(1->2)-D-Glc-alpha-(1->3)-D-Glc-alpha-(1->3)-D-Man- alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha- (1->2)-D-Man-alpha-(1->3)-(D-Man-alpha-(1->2)-D-Man-alpha-(1->6))- D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D- GlcNAc-diphosphodolichol + dolichyl phosphate.
Function Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity).
Pathway Protein modification; protein glycosylation.
Sequence Caution Sequence=AAM75090.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence= ;
Similarity Belongs to the ALG10 glucosyltransferase family.
Subcellular Location Endoplasmic reticulum membrane ; Multi-pass membrane protein .

Identical and Related Proteins

Unique RefSeq proteins for LMP009151 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
24662563 RefSeq NP_729680 449 alpha 3 glucosyltransferase

Identical Sequences to LMP009151 proteins

Reference Database Accession Length Protein Name
GI:24662563 EMBL CAD24126.1 449 putative alpha 3 glucosyltransferase [Drosophila melanogaster]
GI:24662563 gnl FlyBase 449 alpha 3 glucosyltransferase [Drosophila melanogaster]
GI:24662563 SwissProt Q8T8L8.1 449 RecName: Full=Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; AltName: Full=Alpha-2-glucosyltransferase ALG10 [Drosophila melanogaster]

Related Sequences to LMP009151 proteins

Reference Database Accession Length Protein Name
GI:24662563 GenBank AAM75090.1 482 RH44301p, partial [Drosophila melanogaster]
GI:24662563 GenBank EDW41064.1 449 GM25257 [Drosophila sechellia]
GI:24662563 GenBank EDX10051.1 449 GD14291 [Drosophila simulans]
GI:24662563 GenBank AGR42656.1 482 FI21847p1, partial [Drosophila melanogaster]
GI:24662563 RefSeq XP_002030078.1 449 GM25257 [Drosophila sechellia]
GI:24662563 RefSeq XP_002084466.1 449 GD14291 [Drosophila simulans]