Gene/Proteome Database (LMPD)

LMPD ID
LMP009629
Gene ID
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
haloacid dehalogenase-like hydrolase family protein
Gene Symbol
GS1
Synonyms
GLYCEROL-3-PHOSPHATASE 2; GPP2; GS1; MUA2.2; MUA2_2
Alternate Names
haloacid dehalogenase-like hydrolase family protein
Chromosome
5
EC Number
3.1.3.21

Proteins

haloacid dehalogenase-like hydrolase family protein
Refseq ID NP_568858
Protein GI 18423981
UniProt ID Q8VZP1
mRNA ID NM_125126
Length 240
RefSeq Status REVIEWED
MSNPAAVTAGRGSITHVIFDMDGLLLDTEKFYTEVQEIILARFNKKFDWSLKAKMMGRKAIEAARIFVEESGISDSLSAEDFLVERESMLQDLFPTSELMPGASRLIKHLHVKNIPICIATGTHTRHYDLKTQRHRELFSLMHHVVRGDDPEVKQGKPAPDGFLAAARRFKDGPVDSQKVLVFEDAPSGVLAAKNAGMNVVMVPDPRLDISHQDVADQIITSLVDFKPEEWGLPPFEDSN

Gene Information

Entrez Gene ID
Gene Name
haloacid dehalogenase-like hydrolase family protein
Gene Symbol
GS1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005739 IDA:TAIR C mitochondrion
GO:0000121 IEA:UniProtKB-EC F glycerol-1-phosphatase activity
GO:0043136 IDA:UniProtKB F glycerol-3-phosphatase activity
GO:0046872 IEA:UniProtKB-KW F metal ion binding
GO:0016311 IDA:UniProtKB P dephosphorylation
GO:0006114 IMP:UniProtKB P glycerol biosynthetic process

BIOCYC Pathway Links

BIOCYC Pathway ID Description
RIBOSYN2-PWY flavin biosynthesis I (bacteria and plants)

Domain Information

InterPro Annotations

Accession Description
IPR006439 HAD hydrolase, subfamily IA
IPR023214 HAD-like domain

UniProt Annotations

Entry Information

Gene Name
haloacid dehalogenase-like hydrolase family protein
Protein Entry
GPP2_ARATH
UniProt ID
Species
Arabidopsis

Comments

Comment Type Description
Biophysicochemical Properties Kinetic parameters: KM=3.5 mM for DL-glycerol-3-phosphate {ECO:0000269|PubMed:17136424}; Vmax=23 nmol/min/mg enzyme toward DL-glycerol-3-phosphate {ECO:0000269|PubMed:17136424}; pH dependence: Optimum pH is 7.0. {ECO:0000269|PubMed:17136424};
Catalytic Activity Glycerol 1-phosphate + H(2)O = glycerol + phosphate.
Cofactor Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
Function Acts as a glycerol-3-phosphatase with higher stereospecificity for L-glycerol-3-phosphate than DL-glycerol-3- phosphate. {ECO:0000269|PubMed:17136424}.
Sequence Caution Sequence=BAB08780.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Similarity Belongs to the HAD-like hydrolase superfamily. DOG/GPP family. {ECO:0000305}.
Subcellular Location Cytoplasm {ECO:0000305|PubMed:17136424}.
Tissue Specificity Ubiquitous with highest expression in siliques. Mainly restricted to the meristem of immature flower and vascular elements of the root, shoot, leave, siliqua and developing embryo (at the protein level). {ECO:0000269|PubMed:17136424}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009629 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
18423981 RefSeq NP_568858 240 haloacid dehalogenase-like hydrolase family protein

Identical Sequences to LMP009629 proteins

Reference Database Accession Length Protein Name
GI:18423981 GenBank AAL36323.1 240 putative GS1 protein [Arabidopsis thaliana]
GI:18423981 GenBank AAM45079.1 240 putative GS1 protein [Arabidopsis thaliana]
GI:18423981 GenBank AAM61099.1 240 GS1-like protein [Arabidopsis thaliana]
GI:18423981 gnl TAIR 240 haloacid dehalogenase-like hydrolase family protein [Arabidopsis thaliana]
GI:18423981 SwissProt Q8VZP1.1 240 RecName: Full=(DL)-glycerol-3-phosphatase 2; AltName: Full=Glycerol-1-phosphatase 2; AltName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein GPP2 [Arabidopsis thaliana]

Related Sequences to LMP009629 proteins

Reference Database Accession Length Protein Name
GI:18423981 EMBL CDY38298.1 238 BnaA10g11460D [Brassica napus]
GI:18423981 GenBank EFH42465.1 239 glycerol-3-phosphatase 2 [Arabidopsis lyrata subsp. lyrata]
GI:18423981 GenBank EOA12394.1 239 hypothetical protein CARUB_v10027031mg [Capsella rubella]
GI:18423981 RefSeq XP_002866206.1 239 glycerol-3-phosphatase 2 [Arabidopsis lyrata subsp. lyrata]
GI:18423981 RefSeq XP_006279496.1 239 hypothetical protein CARUB_v10027031mg [Capsella rubella]
GI:18423981 RefSeq XP_009120262.1 238 PREDICTED: (DL)-glycerol-3-phosphatase 2 [Brassica rapa]