Gene/Proteome Database (LMPD)

LMPD ID
LMP009657
Gene ID
842536
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
1-aminocyclopropane-1-carboxylate oxidase 2
Gene Symbol
ACO2
Synonyms
ACC OXIDASE; ACC oxidase 2; ACO2; ATACO2; F24O1.40; F24O1_40
Alternate Names
1-aminocyclopropane-1-carboxylate oxidase 2
Chromosome
1
EC Number
1.14.17.4
Summary
Encodes a protein similar to 1-aminocyclopropane-1-carboxylic oxidase (ACC oxidase). Expression of the AtACO2 transcripts is affected by ethylene.
Orthologs
View orthologs and multiple alignments for ACO2

Proteins

1-aminocyclopropane-1-carboxylate oxidase 2
Refseq ID NP_176428
Protein GI 15220770
UniProt ID Q41931
mRNA ID NM_104918
Length 320
RefSeq Status REVIEWED
MEKNMKFPVVDLSKLNGEERDQTMALINEACENWGFFEIVNHGLPHDLMDKIEKMTKDHYKTCQEQKFNDMLKSKGLDNLETEVEDVDWESTFYVRHLPQSNLNDISDVSDEYRTAMKDFGKRLENLAEDLLDLLCENLGLEKGYLKKVFHGTKGPTFGTKVSNYPPCPKPEMIKGLRAHTDAGGIILLFQDDKVSGLQLLKDGDWIDVPPLNHSIVINLGDQLEVITNGKYKSVLHRVVTQQEGNRMSVASFYNPGSDAEISPATSLVEKDSEYPSFVFDDYMKLYAGVKFQPKEPRFAAMKNASAVTELNPTAAVETF

Gene Information

Entrez Gene ID
842536
Gene Name
1-aminocyclopropane-1-carboxylate oxidase 2
Gene Symbol
ACO2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005794 IDA:TAIR C Golgi apparatus
GO:0005618 IDA:TAIR C cell wall
GO:0005829 IDA:TAIR C cytosol
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0005886 IDA:TAIR C plasma membrane
GO:0009506 IDA:TAIR C plasmodesma
GO:0009815 ISS:TAIR F 1-aminocyclopropane-1-carboxylate oxidase activity
GO:0031418 IEA:UniProtKB-KW F L-ascorbic acid binding
GO:0005507 IDA:TAIR F copper ion binding
GO:0016706 IEA:InterPro F oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0071398 IEP:UniProtKB P cellular response to fatty acid
GO:0071281 IEP:TAIR P cellular response to iron ion
GO:0071732 IEP:UniProtKB P cellular response to nitric oxide
GO:0006952 IEA:UniProtKB-KW P defense response
GO:0009727 IDA:TAIR P detection of ethylene stimulus
GO:0009693 TAS:TAIR P ethylene biosynthetic process
GO:0010030 IMP:UniProtKB P positive regulation of seed germination
GO:0009735 IDA:TAIR P response to cytokinin
GO:0009651 IEP:TAIR P response to salt stress

KEGG Pathway Links

KEGG Pathway ID Description
ath01110 Biosynthesis of secondary metabolites
ath00270 Cysteine and methionine metabolism
ath_M00368 Ethylene biosynthesis, methionine => ethylene
ath01100 Metabolic pathways

Domain Information

InterPro Annotations

Accession Description
IPR027443 Isopenicillin N synthase-like
IPR026992 Non-haem dioxygenase N-terminal domain
IPR005123 Oxoglutarate/iron-dependent dioxygenase

UniProt Annotations

Entry Information

Gene Name
1-aminocyclopropane-1-carboxylate oxidase 2
Protein Entry
ACCO2_ARATH
UniProt ID
Q41931
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity 1-aminocyclopropane-1-carboxylate + ascorbate + O(2) = ethylene + cyanide + dehydroascorbate + CO(2) + 2 H(2)O.
Cofactor Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000255|PROSITE-ProRule:PRU00805, ECO:0000269|PubMed:20018591}; Name=Cu(2+); Xref=ChEBI:CHEBI:29036; Evidence={ECO:0000255|PROSITE-ProRule:PRU00805, ECO:0000269|PubMed:20018591}; Note=Binds 1 Fe(2+) ion per subunit. Can also bind Cu(2+) ions. {ECO:0000255|PROSITE-ProRule:PRU00805, ECO:0000269|PubMed:20018591};
Disruption Phenotype Impaired in the 1-aminocyclopropane-1- carboxylic acid (ACC)-mediated reversion of the ABA-induced inhibition of seed germination. {ECO:0000269|PubMed:20023197}.
Function Enzyme involved in the ethylene biosynthesis. Required to mediate the 1-aminocyclopropane-1-carboxylic acid (ACC)- mediated reversion of the ABA-induced inhibition of seed germination via endosperm rupture. May promote stem elongation by maximizing the extensibility cells, possibly by activating ethylene biosynthesis, in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0). {ECO:0000269|PubMed:17993622, ECO:0000269|PubMed:20023197}.
Induction Upon iron deprivation. Induced by ethylene, particularly in root tips and hooks of ethiolated seedlings. Promoted by ozone O(3). Accumulates in response to very-long-chain fatty acids (VLCFAs C20:0 to C30:0). Induced in roots by nitric oxide (NO). {ECO:0000269|PubMed:10409511, ECO:0000269|PubMed:15272873, ECO:0000269|PubMed:15728341, ECO:0000269|PubMed:16920797, ECO:0000269|PubMed:17993622, ECO:0000269|PubMed:20627899, ECO:0000269|PubMed:21316254}.
Pathway Alkene biosynthesis; ethylene biosynthesis via S- adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 2/2.
Similarity Belongs to the iron/ascorbate-dependent oxidoreductase family. {ECO:0000305}.
Similarity Contains 1 Fe2OG dioxygenase domain. {ECO:0000255|PROSITE-ProRule:PRU00805}.
Tissue Specificity Expressed in vegetative tissues. Constitutively expressed in leaves and blades. In ethylene exposed etiolated seedlings, localized in cells at the outer side of the exaggerated hook in an ethylene-dependent manner and following an ethylene sensitive pattern. Also detected in the root tip when treated by ethylene. {ECO:0000269|PubMed:10409511, ECO:0000269|PubMed:12972669, ECO:0000269|PubMed:17993622}.

Identical and Related Proteins

Unique RefSeq proteins for LMP009657 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15220770 RefSeq NP_176428 320 1-aminocyclopropane-1-carboxylate oxidase 2

Identical Sequences to LMP009657 proteins

Reference Database Accession Length Protein Name
GI:15220770 DBBJ BAF02150.1 320 hypothetical protein [Arabidopsis thaliana]
GI:15220770 GenBank AAM91785.1 320 putative ACC oxidase [Arabidopsis thaliana]
GI:15220770 GenBank ACW98825.1 320 Sequence 19610 from patent US 7569389
GI:15220770 GenBank ACW99212.1 320 Sequence 20135 from patent US 7569389
GI:15220770 GenBank AEE33960.1 320 1-aminocyclopropane-1-carboxylate oxidase 2 [Arabidopsis thaliana]
GI:15220770 SwissProt Q41931.2 320 RecName: Full=1-aminocyclopropane-1-carboxylate oxidase 2; Short=ACC oxidase 2; Short=AtACO2 [Arabidopsis thaliana]

Related Sequences to LMP009657 proteins

Reference Database Accession Length Protein Name
GI:15220770 GenBank AAC27484.1 320 ACC oxidase [Arabidopsis thaliana]
GI:15220770 GenBank ACW97318.1 320 Sequence 17550 from patent US 7569389
GI:15220770 GenBank ACX05464.1 320 Sequence 28660 from patent US 7569389
GI:15220770 GenBank EFH64288.1 320 hypothetical protein ARALYDRAFT_475105 [Arabidopsis lyrata subsp. lyrata]
GI:15220770 GenBank AFI41198.1 320 ACC oxidase 2, partial [Arabidopsis thaliana]
GI:15220770 RefSeq XP_002888029.1 320 hypothetical protein ARALYDRAFT_475105 [Arabidopsis lyrata subsp. lyrata]