Gene/Proteome Database (LMPD)

LMPD ID
LMP010080
Gene ID
836003
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
cytochrome P450 86A1
Gene Symbol
CYP86A1
Synonyms
CYP86; CYP86A1; cytochrome P450; family 86; K19M22.14; K19M22_14; polypeptide 1; subfamily A
Alternate Names
cytochrome P450 86A1
Chromosome
5
EC Number
1.14.14.1

Proteins

cytochrome P450 86A1
Refseq ID NP_200694
Protein GI 15237768
UniProt ID P48422
mRNA ID NM_125276
Length 513
RefSeq Status REVIEWED
MEALNSILTGYAVAALSVYALWFYFLSRRLTGPKVLPFVGSLPYLIANRSRIHDWIADNLRATGGTYQTCTMVIPFVAKAQGFYTVTCHPKNVEHILKTRFDNYPKGPMWRAAFHDLLGQGIFNSDGDTWLMQRKTAALEFTTRTLRQAMARWVNGTIKNRLWLILDRAVQNNKPVDLQDLFLRLTFDNICGLTFGKDPETLSLDLPDNPFSVAFDTATEATLKRLLYTGFLWRIQKAMGIGSEDKLKKSLEVVETYMNDAIDARKNSPSDDLLSRFLKKRDVNGNVLPTDVLQRIALNFVLAGRDTSSVALSWFFWLVMNNREVETKIVNELSMVLKETRGNDQEKWTEEPLEFDEADRLVYLKAALAETLRLYPSVPQDFKYVVDDDVLPDGTFVPRGSTVTYSIYSIGRMKTIWGEDCLEFRPERWLTADGERFETPKDGYKFVAFNAGPRTCLGKDLAYNQMKSVASAVLLRYRVFPVPGHRVEQKMSLTLFMKNGLRVYLQPRGEVLA

Gene Information

Entrez Gene ID
836003
Gene Name
cytochrome P450 86A1
Gene Symbol
CYP86A1
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0005773 IDA:TAIR C vacuole
GO:0018685 IDA:TAIR F alkane 1-monooxygenase activity
GO:0070330 IEA:UniProtKB-EC F aromatase activity
GO:0020037 IEA:InterPro F heme binding
GO:0005506 IEA:InterPro F iron ion binding
GO:0006631 IDA:TAIR P fatty acid metabolic process
GO:0010345 IMP:TAIR P suberin biosynthetic process

KEGG Pathway Links

KEGG Pathway ID Description
ath00073 Cutin, suberine and wax biosynthesis
ko00073 Cutin, suberine and wax biosynthesis

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-1121 suberin biosynthesis
PWY-1121 suberin monomers biosynthesis

Domain Information

InterPro Annotations

Accession Description
IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR017972 Cytochrome P450, conserved site

UniProt Annotations

Entry Information

Gene Name
cytochrome P450 86A1
Protein Entry
C86A1_ARATH
UniProt ID
P48422
Species
Arabidopsis

Comments

Comment Type Description
Catalytic Activity RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.
Cofactor Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Function Catalyzes the omega-hydroxylation of various fatty acids (FA). Acts on saturated and unsaturated fatty acids with chain lengths from C12 to C18 but not on hexadecane. {ECO:0000269|PubMed:15709153, ECO:0000269|PubMed:17427946}.
Induction By abscisic acid (ABA), the ethylene precursor ACC, mannitol or cold treatment. Down-regulated by auxin and salicylic acid (SA). {ECO:0000269|PubMed:15709153}.
Similarity Belongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular Location Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in roots. {ECO:0000269|PubMed:15709153}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010080 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15237768 RefSeq NP_200694 513 cytochrome P450 86A1

Identical Sequences to LMP010080 proteins

Reference Database Accession Length Protein Name
GI:15237768 DBBJ BAB09631.1 513 cytochrome P450 [Arabidopsis thaliana]
GI:15237768 gnl TAIR 513 cytochrome P450 86A1 [Arabidopsis thaliana]
GI:15237768 SwissProt P48422.2 513 RecName: Full=Cytochrome P450 86A1; AltName: Full=CYPLXXXVI; AltName: Full=P450-dependent fatty acid omega-hydroxylase; AltName: Full=Protein HYDROXYLASE OF ROOT SUBERIZED TISSUE [Arabidopsis thaliana]

Related Sequences to LMP010080 proteins

Reference Database Accession Length Protein Name
GI:15237768 EMBL CAA62082.1 513 cytochrome p450 [Arabidopsis thaliana]
GI:15237768 GenBank AAL91155.1 513 cytochrome P450 [Arabidopsis thaliana]
GI:15237768 GenBank AAO29963.1 513 cytochrome P450 [Arabidopsis thaliana]
GI:15237768 GenBank EFH38894.1 513 cytochrome P450 [Arabidopsis lyrata subsp. lyrata]
GI:15237768 RefSeq XP_002862636.1 513 cytochrome P450 [Arabidopsis lyrata subsp. lyrata]
GI:15237768 RefSeq XP_010454344.1 513 PREDICTED: cytochrome P450 86A1 [Camelina sativa]