Gene/Proteome Database (LMPD)

LMPD ID
LMP010212
Gene ID
827835
Species
Arabidopsis thaliana (Arabidopsis)
Gene Name
fatty acid hydroxylase 2
Gene Symbol
FAH2
Synonyms
ARABIDOPSIS FATTY ACID HYDROXYLASE 2; ATFAH2; FAH2; fatty acid hydroxylase 2; T13K14.30; T13K14_30
Alternate Names
fatty acid hydroxylase 2
Chromosome
4
EC Number
1.-.-.-
Summary
encodes a fatty acid hydroxylase, required for the AtBI-1-mediated suppression of programmed cell death.
Orthologs
View orthologs and multiple alignments for FAH2

Proteins

fatty acid hydroxylase 2
Refseq ID NP_193819
Protein GI 15233426
UniProt ID Q9SUC5
mRNA ID NM_118205
Length 237
RefSeq Status REVIEWED
MVAERYTVDLNKPLVFQVGHLGEEYQEWIHQPIVCVEGPRFFESDFWEFLTRTVWWAIPTIWLPVVCYVLSISASKGLTFPQIGLIVAFGVLTWTLLEYTLHRFLFHIQTKSYWANTAHYLLHGCHHKHPQDGLRLVFPPTATAILLVPLWKLLHLLATPATAPAILGGILFGYVMYDITHYYLHHGQPKEPTFKHLKKYHLNHHFRIQDKGYGITSSLWDKVFGTLPGIKAAAKKS

Gene Information

Entrez Gene ID
827835
Gene Name
fatty acid hydroxylase 2
Gene Symbol
FAH2
Species
Arabidopsis thaliana

Gene Ontology (GO Annotations)

GO ID Source Type Description
GO:0005783 IDA:TAIR C endoplasmic reticulum
GO:0016021 IEA:UniProtKB-KW C integral component of membrane
GO:0080132 IGI:TAIR F fatty acid alpha-hydroxylase activity
GO:0005506 IEA:InterPro F iron ion binding
GO:0006633 IEA:InterPro P fatty acid biosynthetic process
GO:0043069 IGI:TAIR P negative regulation of programmed cell death

BIOCYC Pathway Links

BIOCYC Pathway ID Description
PWY-5129 sphingolipid biosynthesis (plants)

Domain Information

InterPro Annotations

Accession Description
IPR006694 Fatty_acid_hydroxylase

UniProt Annotations

Entry Information

Gene Name
fatty acid hydroxylase 2
Protein Entry
FAH2_ARATH
UniProt ID
Q9SUC5
Species
Arabidopsis

Comments

Comment Type Description
Disruption Phenotype No visible phenotype under normal growth conditions. {ECO:0000269|PubMed:22635113}.
Function Fatty acid 2-hydroxylase involved in the alpha- hydroxylation of the long-chain fatty acid (LCFA) palmitic acid. Probably involved in the resistance response to oxidative stress. {ECO:0000269|PubMed:19054355, ECO:0000269|PubMed:22635113}.
Induction Not induced by H(2)O(2) treatment. {ECO:0000269|PubMed:22635113}.
Interaction O48845:CYTB5-B; NbExp=3; IntAct=EBI-2296064, EBI-2295402;
Similarity Belongs to the sterol desaturase family. {ECO:0000305}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:19054355}; Multi-pass membrane protein {ECO:0000269|PubMed:19054355}.
Subunit Interacts with CYTB5-A, CYTB5-B, CYTB5-C and CYTB5-D. {ECO:0000269|PubMed:19054355}.

Identical and Related Proteins

Unique RefSeq proteins for LMP010212 (as displayed in Record Overview)

Protein GI Database Accession Length Protein Name
15233426 RefSeq NP_193819 237 fatty acid hydroxylase 2

Identical Sequences to LMP010212 proteins

Reference Database Accession Length Protein Name
GI:15233426 EMBL CAB79087.1 237 fatty acid hydroxylase-like protein [Arabidopsis thaliana]
GI:15233426 GenBank AAK73256.1 237 fatty acid hydroxylase-like protein [Arabidopsis thaliana]
GI:15233426 GenBank AAL25567.1 237 AT4g20870/T13K14_30 [Arabidopsis thaliana]
GI:15233426 GenBank AAM26659.1 237 AT4g20870/T13K14_30 [Arabidopsis thaliana]
GI:15233426 GenBank AEE84370.1 237 fatty acid hydroxylase 2 [Arabidopsis thaliana]
GI:15233426 SwissProt Q9SUC5.1 237 RecName: Full=Fatty acid 2-hydroxylase 2; Short=AtFAH2 [Arabidopsis thaliana]

Related Sequences to LMP010212 proteins

Reference Database Accession Length Protein Name
GI:15233426 GenBank EFH44131.1 237 hypothetical protein ARALYDRAFT_914595 [Arabidopsis lyrata subsp. lyrata]
GI:15233426 GenBank EOA17348.1 237 hypothetical protein CARUB_v10005630mg [Capsella rubella]
GI:15233426 RefSeq XP_002867872.1 237 hypothetical protein ARALYDRAFT_914595 [Arabidopsis lyrata subsp. lyrata]
GI:15233426 RefSeq XP_006284450.1 237 hypothetical protein CARUB_v10005630mg [Capsella rubella]
GI:15233426 RefSeq XP_009134054.1 237 PREDICTED: fatty acid 2-hydroxylase 2 [Brassica rapa]
GI:15233426 RefSeq XP_010434263.1 238 PREDICTED: fatty acid 2-hydroxylase 2 [Camelina sativa]